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SLC1A1 encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. Additionally we are shipping Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 Kits (4) and Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 Proteins (4) and many more products for this protein.
Showing 10 out of 94 products:
Human Monoclonal SLC1A1 Primary Antibody for IP, WB - ABIN2482755
Smith, Weremowicz, Kanai, Stelzner, Morton, Hediger: Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: potential role in dicarboxylic aminoaciduria and neurodegenerative disorders. in Genomics 1994
Show all 2 references for ABIN2482755
Human Monoclonal SLC1A1 Primary Antibody for IP, WB - ABIN2482757
Kanai, Hediger: Primary structure and functional characterization of a high-affinity glutamate transporter. in Nature 1992
Show all 2 references for ABIN2482757
Human Polyclonal SLC1A1 Primary Antibody for IHC, ELISA - ABIN1584382
Kawamoto, Scavone, Mattson, Camandola: Curcumin requires tumor necrosis factor α signaling to alleviate cognitive impairment elicited by lipopolysaccharide. in Neuro-Signals 2013
Cow (Bovine) Polyclonal SLC1A1 Primary Antibody for WB - ABIN2781599
Ruggiero, Liu, Vidensky, Maier, Jung, Farhan, Robinson, Sitte, Rothstein: The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein. in The Journal of biological chemistry 2008
Lithium-sensitive GSK3ss is a powerful regulator of excitatory amino acid transporters EAAT3 and EAAT4 (show SLC1A6 Antibodies).
Data suggest that EAAC1 transporters present on NST (show SULT4A1 Antibodies) dendrites may play a minor role if any in glutamate (show GRIN1 Antibodies) clearance.
SPAK (show STK39 Antibodies) and OSR1 (show OXSR1 Antibodies) are negative regulators of EAAT3 activity
Excitatory amino acid carrier 1 (EAAC1) plays a pivotal role in neuronal glutathione synthesis to maintain cellular redox homeostasis.
Transport of either L-glutamate (show GRIN1 Antibodies) or L-selenocysteine by EAAT3 decreased intracellular pH, whereas transport of cysteine resulted in cytoplasmic alkalinization.
variability within the SLC1A1 gene impacts both the presence and severity of posttraumatic stress disorder among a sample of combat-exposed veterans.
Our data suggest that SLC1A1 is unlikely to be a major susceptibility gene for schizophrenia in Han Chinese
Results indentify plausible candidates include non-recurrent deletions at the glutamate transporter gene SLC1A1, a CNV locus recently suggested to be involved in schizophrenia through linkage analysis, and duplications at 1p36.33 and CGNL1 (show CGNL1 Antibodies).
internalization of EAAT3 triggered by amphetamine increases glutamatergic signaling and thus contributes to the effects of amphetamine on neurotransmission.
EAAT3/EAAC1 expression is altered in pathological conditions, such as hypoxia/ischemia, multiple sclerosis, schizophrenia, and epilepsy. (Review)
These findings suggest that cysteine uptake by EAAC1 is important for neuronal antioxidant function under ischemic conditions.
these studies indicate that absence of EAAC1 results in either a decrease in pilocarpine-induced seizures that is not detectable by behavioral criteria
EAAT3 is upstream of PKA in a pathway to regulate GluR1 (show GRIA1 Antibodies) trafficking.
EAAT3/EAAC1 expression is altered in murine models of human neurodegenerative diseases. (Review)
These results suggest that the isoflurane preconditioning-induced acute phase of neuroprotection involves EAAT3.
These findings indicate that regulation of heart rate, a vital sign, is one of the EAAT (show SLC1A2 Antibodies) biological functions.
Study implicates EAAC1-dependent cysteine uptake as an endogenous source of enhancing antioxidant function and zinc homeostasis in neurons in the ischemic brain.
This study showed that these relatively small amounts of EAAC1 protein are widely distributed in somata and dendrites of all hippocampal neurons.
These findings identify a mechanism whereby Nrf2 (show NFE2L2 Antibodies) activation can coordinate astrocyte glutathione release with neuronal glutathione synthesis through transcriptional upregulation of neuronal EAAT3 expression.
EAAT3 is important in limiting ischemic brain injury after focal brain ischemia
Data suggest that expression of SLC1A1 in intestinal epithelial cells can be regulated by dietary components; expression of SLC1A1 is up-regulated by L-glutamate (show GRIN2C Antibodies), an abundant dietary amino acid and dietary supplement.
These findings indicate that the expression of the EAAC1 in jejunum is much depending on the stage of piglet development and that low BW at birth is associated with lower expression of this carrier in the early suckling period.
Glutamate (show GRIN2C Antibodies) uptake across apical membrane is regulated by changing expression of EAAC-1 at transcription and translation levels as well as maximal uptake activity and transporter affinity along the intestinal crypt-villus axis in the neonate.
This study is focused on the assessment of non-exocytotic glutamate (show GRIN2A Antibodies) release, that is, the unstimulated release, heteroexchange and glutamate transporter reversal in platelets.
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter glutamate, and in maintaining extracellular glutamate concentrations below neurotoxic levels. This transporter also transports aspartate, and mutations in this gene are thought to cause dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect.
excitatory amino acid transporter 3
, excitatory amino acid carrier 1
, neuronal and epithelial glutamate transporter
, sodium-dependent glutamate/aspartate transporter 3
, solute carrier family 1 member 1
, excitatory amino acid carrier 2
, excitatory amino-acid carrier 1
, glutamate transporter mEAAC2
, solute carrier family 1, member 1
, Solute carrier family 1 A1 (brain glutamate transporter)
, excitatory amino acid transporter-3
, glutamate transporter
, renal high affinity glutamate transporter EAAC1
, high-affinity glutamate transporter