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anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) Antibodies

SLC11A2 encodes a member of the solute carrier family 11 protein family. Additionally we are shipping Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 Kits (12) and Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC11A2 25715 O54902
SLC11A2 4891 P49281
SLC11A2 18174 P49282
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Top anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC11A2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated IF, WB Confocal immunofluorescent analysis of SLC11A2 Antibody (Center)  with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). SLC11A2 Antibody (Center)  western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the SLC11A2 antibody detected the SLC11A2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SLC11A2 on formalin-fixed paraffin-embedded human endometrium cancer. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged SLC11A2 is 0.03 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-SLC11A2 antibody  ABIN1049329 IHC staining of human, kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-SLC11A2 antibody  ABIN1049329 IHC staining of human, pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SLC11A2 on formalin-fixed paraffin-embedded human endometrium cancer (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-SLC11A2 antibody  ABIN960802 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-SLC11A2 antibody  ABIN960802 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details

SLC11A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 Antibodies

  1. Mouse (Murine) Polyclonal SLC11A2 Primary Antibody for IF, WB - ABIN657723 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 5 references for ABIN657723

  2. Human Monoclonal SLC11A2 Primary Antibody for IHC (p), ELISA - ABIN562043 : Foot, Dalton, Shearwin-Whyatt, Dorstyn, Tan, Yang, Kumar: Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2. in Blood 2008 (PubMed)
    Show all 4 references for ABIN562043

  3. Human Polyclonal SLC11A2 Primary Antibody for WB - ABIN2781546 : Nevo: Site-directed mutagenesis investigation of coupling properties of metal ion transport by DCT1. in Biochimica et biophysica acta 2008 (PubMed)

More Antibodies against Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 Interaction Partners

Zebrafish Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) interaction partners

  1. The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1). Whereas wild-type zebrafish DMT1 protein can transport iron, the truncated protein expressed in cdy mutants is not functional.

Human Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) interaction partners

  1. Gene silencing of either CTR1 (show SLC31A1 Antibodies) or DMT1 (show DMRT1 Antibodies) did not affect copper accumulation in cells, but deficiency in both CTR1 (show SLC31A1 Antibodies) and DMT1 (show DMRT1 Antibodies) resulted in a complete inhibition of copper uptake.

  2. These data suggest that iron uptake induces the production of ROS (show ROS1 Antibodies), which modify DMT1 (show DMRT1 Antibodies) endocytic cycling, thus changing the iron transport activity at the apical membrane.

  3. We propose that DMT1 (show DMRT1 Antibodies) deficiency negatively affects metabolism and life span of mature erythrocytes; two other aspects of defective erythropoiesis which contribute to the pathophysiology of the disease

  4. Suggest role for divalent cation transporter DMT1 (show DMRT1 Antibodies) in the entry of Hg(II) into the intestinal epithelium.

  5. Six months after RYGB surgery, patients exhibit an increase in DMT1 (show DMRT1 Antibodies) expression in the enterocytes of the tips of the villi at the proximal jejunum

  6. In Parkinson's disease, increased iron levels are associated with increased Ndfip1 (show NDFIP1 Antibodies) expression for the regulation of DMT1 (show DMRT1 Antibodies), including abnormal Ndfip1 (show NDFIP1 Antibodies) activation in non-neuronal cell types such as astrocytes.

  7. The DMT1 (show DMRT1 Antibodies) IVS4 C(+) allele occurred more frequently in WND (show ATP7B Antibodies) than in the healthy controls.

  8. DMT1 (show DMRT1 Antibodies) not only exports iron from endosomes, but also serves to import the metal into the mitochondria

  9. Manganese (Mn) transport carriers DMT1 (show DMRT1 Antibodies) and FPN1 (show SLC40A1 Antibodies) mediate the apical uptake and basolateral exit of Mn in colonic epithelial Caco-2 cells.

  10. DMT1 (show DMRT1 Antibodies) is likely involved in endosomal iron transport in placental STB and placental DMT1 (show DMRT1 Antibodies) + IRE expression was primarily regulated by the IRE/IRP (show WNT2 Antibodies) mechanism

Mouse (Murine) Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) interaction partners

  1. PrP(C (show PRNP Antibodies)) promotes, and possibly regulates, the uptake of iron through DMT1 and Zip14 (show SLC39A14 Antibodies) via its ferrireductase activity.

  2. This study reveals a critical function for DMT1 in intestinal nonheme-iron absorption for normal growth and development, and that it is not required for the transport of copper, manganese, or zinc.

  3. We propose that DMT1 deficiency negatively affects metabolism and life span of mature erythrocytes; two other aspects of defective erythropoiesis which contribute to the pathophysiology of the disease

  4. Misregulation of DMT1 is implicated in Parkinson's disease.

  5. Suggest role for divalent cation transporter DMT1 in the entry of Hg(II) into the intestinal epithelium.

  6. The Cu uptake in HEK293 cells that over-expressed the 2/-IRE isoform of DMT1 transporter supports our earlier contention that DMT1 transports Cu as Cu(1+).

  7. Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin (show Tf Antibodies)-bound iron uptake in mice.

  8. DMT-1 expression in hypothalamic subregions is cre recombinase (show RAG1 Antibodies) sensitive, and that central-peripheral pathways may impact beta cell function in the Dmt1 null mouse.

  9. CD61 (show ITGB3 Antibodies) regulates the expression of Slc11a2, which is involved in iron transportation in epithelial tissues.

  10. that 1B/(-)IRE DMT1 expression and intracellular iron influx are early downstream responses to NF-kappaB (show NFKB1 Antibodies)/RelA (show NFkBP65 Antibodies) activation and acetylation during brain ischemia and contribute to the pathogenesis of stroke-induced neuronal damage

Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2) Antigen Profile

Protein Summary

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC11A2

  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (SLC11A2) antibody
  • metal transporter NRAMP2 (NRAMP2) antibody
  • manganese transport protein (NRAMP2) antibody
  • NRAMP2 (ARALYDRAFT_891495) antibody
  • solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 (slc11a2) antibody
  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (slc11a2) antibody
  • solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 (Slc11a2) antibody
  • solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 (SLC11A2) antibody
  • solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 (Slc11a2) antibody
  • ATNRAMP2 antibody
  • cb426 antibody
  • DCT1 antibody
  • Dmt1 antibody
  • F8G22.4 antibody
  • F8G22_4 antibody
  • fa07b10 antibody
  • MGC138014 antibody
  • mk antibody
  • Nramp2 antibody
  • NRAMP metal ion transporter 2 antibody
  • SLC11A2 antibody
  • van antibody
  • wu:fa07b10 antibody
  • zgc:136699 antibody

Protein level used designations for SLC11A2

divalent metal transporter 1 , natural resistance-associated macrophage protein 2 , manganese transport protein , NRAMP2 , solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 , cdy , chardonnay , nramp , DMT-1 , NRAMP 2 , Solute carrier family 11 member 2 (natural resistance-associated macrophage protein 2) , divalent cation transporter 1 , microcytic anemia, viable anaemia

GENE ID SPECIES
733595 Sus scrofa
751817 Gallus gallus
841127 Arabidopsis thaliana
5726598 Chlamydomonas reinhardtii
9327403 Arabidopsis lyrata subsp. lyrata
100144712 Xenopus (Silurana) tropicalis
451897 Pan troglodytes
486543 Canis lupus familiaris
512464 Bos taurus
678623 Danio rerio
693986 Macaca mulatta
25715 Rattus norvegicus
4891 Homo sapiens
18174 Mus musculus
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