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anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) Antibodies

The protein encoded by SLC12A2 mediates sodium and chloride transport and reabsorption. Additionally we are shipping SLC12A2 Proteins (9) and SLC12A2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC12A2 6558 P55011
SLC12A2 83629  
SLC12A2 20496 P55012
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Top anti-SLC12A2 Antibodies at antibodies-online.com

Showing 10 out of 72 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SLC12A2  Antibody Titration: 5.0 µg/mL ELISA Titer: 1:1562500  Positive Control: DLD1 cell lysate  SLC12A2 is supported by BioGPS gene expression data to be expressed in DLD1 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti-NKCC1 antibody, IHC(P) IHC(P): Rat Intestine Tissue Anti-NKCC1 antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p) Human, Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Human, Stomach: Formalin-Fixed Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Goat Un-conjugated IHC (p), ELISA Human Colon, Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.1 mg Log in to see 6 to 8 Days
$555.50
Details
Dog Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC (p) Anti-SLC12A2 / NKCC1 antibody  ABIN960803 IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-SLC12A2 / NKCC1 antibody  ABIN960803 IHC staining of human stomach. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details

SLC12A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SLC12A2 Antibodies

  1. Cow (Bovine) Polyclonal SLC12A2 Primary Antibody for WB - ABIN2773831 : Panet, Eliash, Atlan: Na+/K+/Cl- cotransporter activates MAP-kinase cascade downstream to protein kinase C, and upstream to MEK. in Journal of cellular physiology 2005 (PubMed)
    Show all 3 references for ABIN2773831

  2. Human Polyclonal SLC12A2 Primary Antibody for EIA, IHC (fro) - ABIN1109023 : Hannemann, Flatman: Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells. in PLoS ONE 2011 (PubMed)

More Antibodies against SLC12A2 Interaction Partners

Human Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) interaction partners

  1. The NKCC-1 is a Na(+)- dependent Cl(-) transporter that mediates the movement of Na(+), K(+), and Cl(-) ions across the plasma membrane and maintains cell volume and intracellular K(+) and Cl(-) homeostasis.

  2. NKCC1 labeling was seen only in the basolateral membrane of the secretory coils.

  3. Suggest that the expression of NKCC1 in esophageal squamous cell carcinoma may affect the G2/M checkpoint and may be related to the degree of histological differentiation of SCCs.

  4. Functional expression of human NKCC1 from a synthetic cassette-based cDNA: introduction of extracellular epitope tags and removal of cysteines.

  5. our data show a novel role for the WNK1 (show WNK1 Antibodies)/OSR1 (show OXSR1 Antibodies)/NKCC1 pathway in glioma migration

  6. Reduced KCC2 (show SLC12A5 Antibodies)/NKCC1 ratio in the cerebrospinal fluid of Rett Syndrome patients suggests a disturbed process of GABAergic neuronal maturation and open up a new therapeutic perspective.

  7. The hormone aldosterone was found to upregulate NKCC1 by increasing protein stability.

  8. Altered hippocampal area function and coupling in DISC1 (show DISC1 Antibodies) and SLC12A2 minor allele carriers.

  9. The results indicate a role for COMMD1 (show COMMD1 Antibodies) in the regulation of NKCC1 membrane expression and ubiquitination.

  10. These findings suggest that NKCC1 and AQP1 participate in meningioma biology and invasion

Mouse (Murine) Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 2 (SLC12A2) interaction partners

  1. We conclude that TRPV2 (show TRPV2 Antibodies) is involved in osmosensation in skeletal muscle fibres, acting in concert with P-SPAK (show STK39 Antibodies)-activated NKCC1

  2. KCC2 (show SLC12A5 Antibodies) expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses.

  3. GnRH (show GNRH1 Antibodies) neurons were immunopositive for NKCC1 and AE2 (show SLC4A2 Antibodies).

  4. NKCC1 may have a role in periventricular leukomalacia, as shown by bumetanide protection against white matter injury in a rodent model

  5. our results suggest that NKCCs are involved in insulin (show INS Antibodies) secretion and that a single Slc12a2 allele may protect beta-cells from failure due to increased homeostatic expression of Slc12a1 (show SLC12A1 Antibodies).

  6. Repeated stress decreased KCC2 (show SLC12A5 Antibodies) expression and increased NKCC1 expression in membranes of granular and pyramidal cells in the hippocampus.

  7. Data indicate that ion transporter NKCC1 is involved in chloride accumulation but also reveals an impact in neurogenesis.

  8. NKCC1 appeared down regulated in age related hearing loss.

  9. The FAK (show PTK2 Antibodies) inhibitor PF-573,228 augmented shrinkage-induced Src (show SRC Antibodies) phosphorylation, and inhibited shrinkage-induced NKCC1 activity.

  10. in addition to SPAK (show STK39 Antibodies) and OSR1 (show OSR1 Antibodies), WNK4 (show WNK4 Antibodies) is able to anchor itself to the N-terminal domain of NKCC1 and to promote cotransporter activation.

SLC12A2 Antigen Profile

Protein Summary

The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with SLC12A2

  • solute carrier family 12 (sodium/potassium/chloride transporters), member 2 (SLC12A2) antibody
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 2 (SLC12A2) antibody
  • solute carrier family 12 (sodium/potassium/chloride transporter), member 2 (Slc12a2) antibody
  • solute carrier family 12, member 2 (Slc12a2) antibody
  • 9330166H04Rik antibody
  • BSC antibody
  • bsc2 antibody
  • mBSC2 antibody
  • Nkcc1 antibody
  • sy-ns antibody

Protein level used designations for SLC12A2

solute carrier family 12 (sodium/potassium/chloride transporters), member 2 , solute carrier family 12 member 2-like , basolateral Na-K-Cl symporter , bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 , solute carrier family 12 member 2 , solute carrier family 12, member 2 , basolateral NaK(2Cl) cotransporter , sodium/potassium/chloride cotransporters , sodium/potassium/chloride transporters

GENE ID SPECIES
100464321 Ailuropoda melanoleuca
6558 Homo sapiens
83629 Rattus norvegicus
286845 Bos taurus
481490 Canis lupus familiaris
20496 Mus musculus
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