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Solute Carrier Family 13 Member 3 (SLC13A3) ELISA Kits

Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. Additionally we are shipping Solute Carrier Family 13 Member 3 Antibodies (23) and Solute Carrier Family 13 Member 3 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC13A3 SLC13A3 64849 Q8WWT9
Anti-Mouse SLC13A3 SLC13A3 114644 Q91Y63
Anti-Rat SLC13A3 SLC13A3 64846  
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More ELISA Kits for Solute Carrier Family 13 Member 3 Interaction Partners

Human Solute Carrier Family 13 Member 3 (SLC13A3) interaction partners

  1. OAT1 and NaDC3 in the basolateral membrane and OAT4 in the luminal membrane of proximal tubule cells are responsible for the avid renal secretion of N-carbamoylglutamate.

  2. In a study addressing genetic, social, and environmental contributors of chronic kidney disease with tubulointerstitial damages in Sri (show SRI ELISA Kits) Lanka, SNP rs6066043 of SLC13A3 was found attributable risk of 50%.

  3. study concludes NaDC3 present at the basolateral membrane of proximal tubule cells mediates sodium-dependent glutathione (GSH) uptake; the kinetic data show that NaDC3 is a low-affinity GSH transporter

  4. The data 1) reveal alpha-ketoglutarate as a common high-affinity substrate of NaDC3, OAT1 (show KCNK3 ELISA Kits), and OAT3 (show SLC22A8 ELISA Kits)

  5. The results indicate that SLC13A3 is a direct downstream target of PITX2 (show PITX2 ELISA Kits) transcriptional regulation and that levels of PITX2 (show PITX2 ELISA Kits) and SLC13A3 modulate responses to oxidative stress in ocular cells.

  6. NaDC3 promotes cellular senescence probably by inhibiting NAD(+)-dependent SIRT1 (show SIRT1 ELISA Kits).

  7. The narrow substrate specificity prevents interaction of drugs with dicarboxylate-like structure with hNaDC-3 and ensures sufficient support of the proximal tubule cells with alpha-ketoglutarate for anion secretion via organic anion transporter 1 (show SLC22A6 ELISA Kits) or 3.

  8. We provide direct evidence of the localization of NaDC3 at the basolateral membrane of human renal proximal tubule cells and identify a di-hydrophobic amino acid motif VW as basolateral localization signal in the N-terminal cytoplasmic domain of NaDC3.

Mouse (Murine) Solute Carrier Family 13 Member 3 (SLC13A3) interaction partners

  1. demonstrate the membrane translocation of 3OH-GA mediated by NaDC3 and the cis (show CISH ELISA Kits)-inhibitory effect on OCT2 (show SLC22A2 ELISA Kits)-mediated transport of cations

Solute Carrier Family 13 Member 3 (SLC13A3) Antigen Profile

Antigen Summary

Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.

Gene names and symbols associated with SLC13A3

  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (slc13a3) antibody
  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (SLC13A3) antibody
  • solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (Slc13a3) antibody
  • MGC108337 antibody
  • NaDC-3 antibody
  • Nadc3 antibody
  • SDCT2 antibody
  • SLC13A3 antibody
  • zgc:77173 antibody

Protein level used designations for SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 , solute carrier family 13 member 3 , Na(+)/dicarboxylate cotransporter 3 , hNaDC3 , naDC-3 , sodium-dependent high affinity dicarboxylate transporter 3 , sodium-dependent high-affinity dicarboxylate transporter 2 , mNaDC3 , rNaDC3 , sodium-dependent high-affinity dicarboxylate transporter 3

GENE ID SPECIES
548493 Xenopus (Silurana) tropicalis
100029726 Monodelphis domestica
100071226 Equus caballus
458302 Pan troglodytes
405838 Danio rerio
444773 Xenopus laevis
770495 Gallus gallus
64849 Homo sapiens
485910 Canis lupus familiaris
526291 Bos taurus
114644 Mus musculus
64846 Rattus norvegicus
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