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The protein encoded by SLC14A1 is a membrane transporter that mediates urea transport in erythrocytes. Additionally we are shipping Solute Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group) Antibodies (54) and Solute Carrier Family 14 (Urea Transporter), Member 1 (Kidd Blood Group) Proteins (3) and many more products for this protein.
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Data indicate that urea transporter UT-A1 (show SLC14A2 ELISA Kits) successfully trafficking to the apical membrane of the epithelial cells is crucial for the regulation of urea transport.
Reduction or loss of UT-B expression may be related to the incidence, progression and invasiveness of bladder urothelial carcinoma.
Studies indicate that expression of urea transporter UT-B confers high urea permeability to erythrocytes.
Studies indicate that acid substitution in the urea transporter Slc14A1 UT-B protein (show LEPREL2 ELISA Kits) determines the erythrocyte Kidd blood group antigen (show DARC ELISA Kits).
UT-B should be considered as a new member of the water channel (show AQP4 ELISA Kits) family.
High-throughput Kell, Kidd, and Duffy matrix-assisted laser desorption/ionization, time-of-flight mass spectrometry-based blood group (show DARC ELISA Kits) genotyping of 4000 donors shows close to full concordance with serotyping and detects new alleles.
these data confirm the presence of UT-B protein (show LEPREL2 ELISA Kits) within the human bladder.
SLC14A1 could be a unique urea transporter in the bladder that has the ability to influence urine concentration and that this mechanism might explain the increased bladder cancer susceptibility associated with rs10775480.
Inhibitor and mutagenesis studies and results of molecular dynamics simulations suggest that NH and HO pass through the three monomeric urea channels in UT-B.
the rate of urea conduction in UT-B is increased by hypoosmotic stress, and the site of osmoregulation coincides with the location of the energy barrier
We conclude that transgenic expression of UT-A1 (show SLC14A2 ELISA Kits) restores basal urea permeability to the level in wild-type mice but does not restore vasopressin (show AVP ELISA Kits)-stimulated levels of urea permeability. This information suggests that transgenic expression of UT-A1 (show SLC14A2 ELISA Kits) alone in mice lacking UT-A1 (show SLC14A2 ELISA Kits) and UT-A3 (show SLC14A2 ELISA Kits) is sufficient to restore urine-concentrating ability
These results demonstrate that the descending thin limb (DTL (show DTL ELISA Kits)) of the intermediate loop is composed of type I epithelium and expresses both UT-A2 (show SLC14A2 ELISA Kits). The functional role of the DTL (show DTL ELISA Kits) of the intermediate loop may be distinct from the short or long loops.
Studies indicate that urea transporter Slc14a1 UT-B is an indispensable transporter involved in maintaining physiological functions in different tissues.
Data suggest that urea transporter UT-B may play an important role in protecting bladder urothelium by balancing intracellular urea concentration.
AQP9 (show AQP9 ELISA Kits) and unidentified UT-A urea channels constitute primary but redundant urea facilitators in murine hepatocytes
Urea transporter-B-null mice showed defective urine concentrating ability.
UT-B null mice exhibited depression-like behavior, with urea accumulation, nitric oxide reduction, and selective neuronal nitric oxide synthase (show NOS1 ELISA Kits) level increase in hippocampus.
UT-A2 (show SLC14A2 ELISA Kits) deletion in UT-B knockout mice partially remedies the urine concentrating defect caused by UT-B deletion.
UT-B has a role in urinary concentrating ability in mice
Data suggest that expression of UT-B (urea transporter B) in rumen mucosa can be modulated by dietary factors; here, UT-B and AQP3 (aquaglyceroporin-3 (show AQP3 ELISA Kits)) expression are upregulated with solid food intake (low-protein diet of plant forage) at weaning.
Bovine UT-B is expressed in bovine rumen and may function to transport urea into rumen as part of ruminant urea nitrogen salvaging process.
The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system.
Kidd blood group
, SLC14A1 JK
, solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
, urea transporter 1
, urea transporter JK glycoprotein
, urea transporter, erythrocyte
, urea transporter-B1
, solute carrier family 14 member 1
, urea transporter B
, Solute carrier family 14 member 1
, Urea transporter 1
, Urea transporter, erythrocyte
, Urea transporter B