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Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) ELISA Kits

The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. Additionally we are shipping SLC15A2 Antibodies (16) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC15A2 SLC15A2 57738  
Anti-Human SLC15A2 SLC15A2 6565 Q16348
Anti-Rat SLC15A2 SLC15A2 60577  
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More ELISA Kits for SLC15A2 Interaction Partners

Cow (Bovine) Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) interaction partners

  1. Responses of oligopeptide transporter 2 (PepT2) to lactogenic hormones and oligopeptide inferred that it may play an important role in bovine mammary gland.

Zebrafish Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) interaction partners

  1. We characterized the functional properties of a novel zebrafish peptide transporter orthologous to mammalian and avian PEPT2, described its gene (pept2) structure, and determined mRNA tissue distribution

Rabbit Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) interaction partners

  1. Data suggest that USP18 (show USP18 ELISA Kits) (Ubiquitin-like specific protease 18) sensitive cellular functions include activity of the peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2.

  2. SPAK (show STK39 ELISA Kits) is a powerful regulator of peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2

Mouse (Murine) Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) interaction partners

  1. We found marked changes in protein expression and functional activity of PhT1 (show SLC15A4 ELISA Kits) and PepT2, the former predominating in adult and the latter in neonate

  2. JAK3 (show JAK3 ELISA Kits) is a powerful regulator of the peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2.

  3. The study presents a pharmacokinetic model to quantitate the distribution kinetics of glycylsarcosine, a substrate of PepT2, in blood, cerebrospinal fluid and kidney in wild-type and PepT2 knockout mice.

  4. PEPT2 is responsible for dipeptide uptake in choroid plexus tissue

  5. PEPT2 is the main system responsible for tubular reabsorption of peptide-bound amino acids, although this does not lead to major changes in renal excretion of protein or free amino acids.

  6. Studies in transgenic mice demonstrated that PEPT2 was responsible for over 90% of carnosine uptake in choroid plexus. These findings elucidate the unique role of PEPT2 in regulating neuropeptide homeostasis at the blood-cerebrospinal fluid interface

  7. The role of PEPT2 in the uptake of glycylsarcosine and 5-aminolevulinic acid in choroid plexus whole tissue from wild type and knockout mice.

  8. PEPT2-mediated dipeptide transport in enteric glia could contribute to the clearance of neuropeptides in the ENS.

  9. Pept2 mRNA was the highest in kidney, followed by brain and lung

  10. When fed diets with different protein contents, Pept2-/- mice adapted food intake to dietary protein content with higher consumption rates on low protein and reduced food intake rates on the high protein diet.

Human Solute Carrier Family 15 (H+/Peptide Transporter), Member 2 (SLC15A2) interaction partners

  1. PEPT2 is functionally expressed in H441 cells, making the cell line a good in vitro model to study PEPT2 function and its regulation in human distal lung.

  2. In vitro study displayed different response to sorafenib depending on the genotype of SLC15A2.

  3. OSR1 (show OXSR1 ELISA Kits) has the capacity to downregulate the peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2 by decreasing the carrier protein abundance in the cell membrane

  4. JAK3 (show JAK3 ELISA Kits) is a powerful regulator of the peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2.

  5. LNCaP expresses high levels of PEPT2 and PHT1 (show SLC15A4 ELISA Kits).

  6. PEPT1,PEPT2, PHT1, and PHT2 are expressed in human nasal epithelium.

  7. PepT2-mRNA is expressed in U373-MG and glial cells but showed no regulation of PepT2-mRNA expression in both cell types.

  8. Data identify Drosophila Yin and PEPT2 as evolutionarily conserved phagosome-associated transporters.

  9. anserine is recognized by the proton-coupled peptide transporters PEPT1 (show SLC15A1 ELISA Kits) and PEPT2 with medium affinity. Anserine is able to displace other substrates from the transport process.

  10. Higher blood lead burden in children with the PEPT2*2 mutation may suggest that this common genetic variant is a biomarker of increased vulnerability to the neurotoxic effects of lowest level lead exposure.

SLC15A2 Antigen Profile

Antigen Summary

The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995

Gene names and symbols associated with SLC15A2

  • solute carrier family 15 (H+/peptide transporter), member 2 (SLC15A2) antibody
  • solute carrier family 15 (H+/peptide transporter), member 2 (slc15a2) antibody
  • solute carrier family 15 (H+/peptide transporter), member 2 (Slc15a2) antibody
  • solute carrier family 15 (oligopeptide transporter), member 2 (SLC15A2) antibody
  • solute carrier family 15 (oligopeptide transporter), member 2 (Slc15a2) antibody
  • 8430408C16Rik antibody
  • C78862 antibody
  • MGC64416 antibody
  • OPT-3 antibody
  • Pept2 antibody
  • wu:fc84g07 antibody
  • wu:fi22a10 antibody
  • zgc:152684 antibody

Protein level used designations for SLC15A2

peptide transporter 2 , solute carrier family 15 (H+/peptide transporter), member 2 , solute carrier family 15 member 2 , PEPT2 , peptide transporter PEPT2 , proton-dependent dipeptide transporter PEPT2 , solute carrier family 15 member 2-like , H+ coupled di/tri-peptide cotransporter 2 , kidney H(+)/peptide cotransporter , oligopeptide transporter, kidney isoform , Slc15a2 variant A , Slc15a2 variant A2 , proton-dependent high affinity oligopeptide transporter PepT2 , solute carrier family 15, member 2

GENE ID SPECIES
506921 Bos taurus
380090 Xenopus laevis
424244 Gallus gallus
460627 Pan troglodytes
556684 Danio rerio
574375 Macaca mulatta
100070712 Equus caballus
100408111 Callithrix jacchus
100482964 Ailuropoda melanoleuca
100493689 Xenopus (Silurana) tropicalis
100600641 Nomascus leucogenys
488006 Canis lupus familiaris
100048951 Sus scrofa
100009433 Oryctolagus cuniculus
57738 Mus musculus
6565 Homo sapiens
60577 Rattus norvegicus
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