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Solute Carrier Family 19 (Folate Transporter), Member 1 Proteins (SLC19A1)

The membrane protein encoded by SLC19A1 is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Additionally we are shipping SLC19A1 Antibodies (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC19A1 6573 P41440
SLC19A1 20509 P41438
Rat SLC19A1 SLC19A1 29723  
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Top SLC19A1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

SLC19A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) Interaction Partners

Human Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) interaction partners

  1. We conclude that SLC46A1/PCFT (show SLC46A1 Proteins) and SLC19A1/RFC-1 are associated with DFS (show FST Proteins) of patients with colorectal cancer and hypothesize that poor response to 5-fluorouracil plus leucovorin therapy in some patients may be linked to low expression of these genes.

  2. SLC19A1 expression was associated with increased risk of relapse or death, and SLC19A1 expression retained prognostic significance independent of age, disease stage and MYCN (show MYCN Proteins) amplification.

  3. Our findings support the hypothesis that RFC1 (show RFC1 Proteins) A80G variant may contribute to non-syndromic cleft lip and palate susceptibility in a south Indian population.

  4. the RFC-1 (show RFC1 Proteins) -43C>T, 80A>G, and 696T>C polymorphisms may be risk factors for ischemic stroke.

  5. SLC19A1 rs1051266 GG/GA genotype is associated with first trimester fever.

  6. SLC19A1 rs1051296 G>T, a miRNA binding site polymorphism, was associated with increased plasma methotrexate concentrations in Chinese children with acute lymphoblastic leukemia.

  7. SLC19A1 genotype may help to identify patients with increased risk of methotrexate-related toxicity.

  8. The reduced RFC (show RFC1 Proteins) mRNA expression in paclitaxel-resistant osteosarcoma cells may be related to the decrease in intracellular methotrexate concentration.

  9. A significant association was detected between the MTHFR (show MTHFR Proteins) A1298C/ RFC (show RFC1 Proteins) G80A genotype and a nonpredisposition to acute lymphoblastic leukemia.

  10. Present results do not support a role for the RFC-1 (show RFC1 Proteins) c.80G>A polymorphism as independent risk factor for sporadic AD in Italian Caucasians

Mouse (Murine) Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1) interaction partners

  1. The mRNAs encoding Folr2 and the intestinal folate transporter Slc46a1 were not detected in 2-cel embryos and blastocysts.

  2. Interleukin-6 (show IL6 Proteins) regulated the efficacy of methotrexate by decreasing the expression of SLC19A1.

  3. First evidence of RFC expression in rapidly dividing cells of developing neural tube, craniofacial region, limb buds and heart duggests that these regions may be particularly susceptible to folate deficiency.

  4. Inactivation of RFC1 (show RFC1 Proteins) impacts the expression of several ligands and interacting proteins in the cubilin (show CUBN Proteins)-amnionless (show AMN Proteins)-megalin (show LRP2 Proteins) complex that are involved in the maternal-fetal transport of folate and other nutrients.

  5. Intestinal folate uptake process undergoes differentiation-dependent regulation and that this regulation is mediated via changes in the level of expression of both the RFC and PCFT (show SLC46A1 Proteins).

SLC19A1 Protein Profile

Protein Summary

The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC19A1

  • solute carrier family 19 (folate transporter), member 1 (LOC100226745)
  • solute carrier family 19 (folate transporter), member 1 (SLC19A1)
  • solute carrier family 19 (folate transporter), member 1 (Slc19a1)
  • AI323572 protein
  • CHMD protein
  • FOLT protein
  • IFC1 protein
  • LOC100226745 protein
  • MTX1 protein
  • REFC protein
  • RFC protein
  • RFC-1 protein
  • RFC1 protein

Protein level used designations for SLC19A1

solute carrier family 19 (folate transporter), member 1 , IFC-1 , RFC , folate transporter 1 , intestinal folate carrier 1 , placental folate transporter , reduced folate carrier protein , solute carrier family 19 member 1 , intestinal folate carrier protein , reduced folate carrier 1 , solute carrier family 19 (sodium/hydrogen exchanger), member 1 , RFC-1 , RFC1 , methotrexate carrier 1 , methotrexate carrier 2 , methotrexate carrier 5 , methotrexate carrier 6 , solute carrier family 19, member 1 , 58 kDa hydrophobic protein , Folate carrier protein , Methotrexate uptake protein , Solute carrier family 19 member 1

GENE ID SPECIES
100226745 Taeniopygia guttata
6573 Homo sapiens
20509 Mus musculus
29723 Rattus norvegicus
100689407 Cricetulus griseus
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