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Solute Carrier Family 20 (Phosphate Transporter), Member 2 Proteins (SLC20A2)

SLC20A2 encodes a member of the inorganic phosphate transporter family. Additionally we are shipping SLC20A2 Antibodies (24) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC20A2 6575 Q08357
Rat SLC20A2 SLC20A2 29502 Q63488
SLC20A2 20516 Q80UP8
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Top SLC20A2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

SLC20A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Solute Carrier Family 20 (Phosphate Transporter), Member 2 (SLC20A2) Interaction Partners

Human Solute Carrier Family 20 (Phosphate Transporter), Member 2 (SLC20A2) interaction partners

  1. SLC20A2 variant was identified in a family with CHRNB2 mutation, brain calcifications and generalized tonic-clonic seizures.

  2. Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. Three causative genes have been identified: SLC20A2, PDGFRB and, recently, PDGFB, whose associated phenotype has not yet been extensively studied.

  3. A summary of SLC20A2 variants reported in patients with primary familial brain calcification (review).

  4. Currently, mutations in SLC20A2 gene have been identified as pathogenic for Familial idiopathic basal ganglia calcification.

  5. The SLC20A2 mutation leading to the accumulation of calcium salts in the brain.

  6. Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification.

  7. clinical, neuroimaging and genetic findings in an Italian family with idiopathic basal ganglia calcification; 2 affected family members harbored a novel missense mutation, G1618A leading to gly540-to-arg (G540R) substitution in a highly conserved residue

  8. This molecular analysis expands the mutational spectrum of SLC20A2, which remains the major causative gene of primary familial brain calcification.

  9. Familial idiopathic basal ganglia calcification caused by the SLC20A2 gene mutation can manifest as juvenile onset paroxysmal kinesigenic dyskinesia.

  10. The mutation of SLC20A2 cause primary familial brain calcifications.

Mouse (Murine) Solute Carrier Family 20 (Phosphate Transporter), Member 2 (SLC20A2) interaction partners

  1. Slc20a2 is critical for maintaining a physiologic inorganic phosphate level in cerebrospinal fluid

  2. Knockout of Slc20a2 in mice causes calcifications in the thalamus, basal ganglia, and cortex.

  3. PiT-2 is ubiquitously expressed throughout the brain and plays an important role in the maintenance of intracellular inorganic phosphate homeostasis in neurons, astrocytes, and endothelial cells.

  4. Mechanistically, PiT-1 (show POU1F1 Proteins) and PiT-2 seem to serve redundant roles in phosphate-induced calcification of vascular smooth muscle cells.

  5. reduced intestinal Pi absorption in VDR (show CYP27B1 Proteins) (-/-) mice does not seem to be the only factor that causes hypophosphatemia; reduced Npt2a (show SLC34A1 Proteins), Npt2c (show SLC34A3 Proteins), or PiT-2 protein levels during development might also cause hypophosphatemia and rickets in VDR (show CYP27B1 Proteins) (-/-) mice.

  6. Inorganic phosphate effects on Glvr-1 (show SLC20A1 Proteins) and -2 up-regulation require the presence of calcium and involve ERK (show EPHB2 Proteins) signalling pathways.

  7. Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa (show SLC34A1 Proteins), NaPi-IIc, and PiT-2 in dietary potassium deficiency.

SLC20A2 Protein Profile

Protein Summary

This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with SLC20A2

  • solute carrier family 20 (phosphate transporter), member 2 (SLC20A2)
  • solute carrier family 20 (phosphate transporter), member 2 (slc20a2)
  • solute carrier family 20 (phosphate transporter), member 2 (Slc20a2)
  • solute carrier family 20, member 2 (Slc20a2)
  • Ab1-188 protein
  • ChoPit2 protein
  • GLVR-2 protein
  • Glvr2 protein
  • HaPit2 protein
  • IBGC3 protein
  • MLVAR protein
  • MolPit2 protein
  • PiT-2 protein
  • Pit2 protein
  • Ram-1 protein
  • Ram1 protein
  • SLC20A2 protein
  • wu:fi23g11 protein
  • zgc:152990 protein

Protein level used designations for SLC20A2

fi23g11 , sodium-dependent phosphate transporter 2 , solute carrier family 20, member 2 , solute carrier family 20 member 2 , solute carrier family 20 (phosphate transporter), member 2 , sodium-dependent phosphate transporter 2-like , gibbon ape leukemia virus receptor 2 , murine leukemia virus, amphotropic, receptor for , phosphate transporter 2 , receptor for amphitropic viruses 1 , receptor for amphotropic viruses 1 , piT-2 , fePit2 , receptor Pit2 , type III sodium-dependent phosphate transporter , Amphotropic murine leukemia virus receptor , Amphotropic murine retrovirus receptor , Solute carrier family 20 member 2

GENE ID SPECIES
482838 Canis lupus familiaris
558346 Danio rerio
495011 Xenopus laevis
705242 Macaca mulatta
100030175 Monodelphis domestica
100394537 Callithrix jacchus
100442547 Pongo abelii
100590771 Nomascus leucogenys
100609712 Pan troglodytes
6575 Homo sapiens
29502 Rattus norvegicus
518905 Bos taurus
493788 Felis catus
422493 Gallus gallus
20516 Mus musculus
100689023 Cricetulus griseus
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