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anti-Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12) Antibodies

The protein encoded by SLC22A12 is a urate transporter and urate-anion exchanger which regulates the level of urate in the blood. Additionally we are shipping Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 Kits (7) and Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC22A12 20521 Q8CFZ5
SLC22A12 116085 Q96S37
SLC22A12 365398 Q3ZAV1
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Top anti-Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 Antibodies at antibodies-online.com

Showing 10 out of 22 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC22A12 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: DU145 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, WB SLC22A12 monoclonal antibody (M02), clone 2B5. Western Blot analysis of SLC22A12 expression in human stomach. Detection limit for recombinant GST tagged SLC22A12 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$903.83
Details
Human Rabbit Un-conjugated WB SLC22A12 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB Western Blot analysis of SLC22A12 expression in transfected 293T cell line by SLC22A12 MaxPab polyclonal antibody.Lane 1: SLC22A12 transfected lysate(59.60 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Immunohistochemistry of Human brain  using SLC22A12 Polyclonal Antibody at dilution of 1:20 Western blot analysis of Hela and 293T cell, using SLC22A12 Polyclonal Antibody at dilution of 1:200 200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Rabbit Un-conjugated ICC, FACS, IHC (p)   50 μL Log in to see 8 to 10 Days
$551.83
Details

SLC22A12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human ,
,
,
Rat (Rattus)


Top referenced anti-Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 Antibodies

  1. Human Monoclonal SLC22A12 Primary Antibody for ELISA, WB - ABIN530376 : Roncal-Jimenez, Lanaspa, Rivard, Nakagawa, Sanchez-Lozada, Jalal, Andres-Hernando, Tanabe, Madero, Li, Cicerchi, Mc Fann, Sautin, Johnson: Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake. in Metabolism: clinical and experimental 2011 (PubMed)
    Show all 2 references for ABIN530376

  2. Human Polyclonal SLC22A12 Primary Antibody for WB - ABIN2781716 : Kanai: [Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters]. in Nihon rinsho. Japanese journal of clinical medicine 2008 (PubMed)

More Antibodies against Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 Interaction Partners

Mouse (Murine) Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12) interaction partners

  1. The cause of obesity/metabolic syndrome-associated hyperuricemia appears to be associated with the urate reabsorption transporter Urat1 protein enhanced by fat.

  2. Although the fractional excretion of urate of knockout mice was tend to higher than that of wildtype mice, the urate reabsorption ability remained in the kidney of knockout mice, indicating a urate reabsorptive transporter other than Urat1.

  3. mouse RST mediates the efflux of organic anions including urate and works as exit for organic anions in the proximal tubules

  4. NHERF-1 (show SLC9A3R1 Antibodies) exerts a significant effect on the renal tubular reabsorption of uric acid in the mouse by modulating the brush Border membrane abundance of mURAT1.

Human Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12) interaction partners

  1. These results suggest that URAT1 rs3825016 and rs1529909 polymorphisms influence the uricosuric action of losartan

  2. Depletion of UA due to SLC22A12/URAT1 loss-of-function mutations causes endothelial dysfunction in hypouricemia patients.

  3. not only loss-of-function mutation of URAT1 but also the dominant-negative effect cause RHUC through loss of UA absorption, partly due to protein misfolding caused by accumulation of URAT1 protein in the endoplasmic reticulum

  4. Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males.

  5. protein expression of URAT1 and GLUT9 (show SLC2A6 Antibodies) in renal tissues of patients with uric acid (UA) nephrolithiasis

  6. There was no significant mutation found in SLC22A12 and SLC2A9 (show SLC2A9 Antibodies) in this familial aggregation of Chinese female premenopausal gout.

  7. Genetic polymorphisms in the urate transporters SLC2A9 (show SLC2A9 Antibodies), SLC22A12 and non-synonymous allelic variants of GLUT9 (show SLC2A6 Antibodies) showed no evidence of the effect on hyperuricemia and gout in the Czech population.

  8. Our analysis provides evidence for multiple ancestral-specific effects across the SLC22A11 (show SLC22A11 Antibodies)/SLC22A12 locus that presumably influence the activity of OAT4 (show SLC22A9 Antibodies) and URAT1 and risk of gout.

  9. Our study is the first one in Turkish population and suggests that there is no association between primary gout disease and SLC22A12 gene polymorphisms.

  10. analysis of mutations in genes SLC22A12 and SLC2A9 (show SLC2A9 Antibodies) urate transporter (show LGALS9 Antibodies) genes in patients with exercise-induced acute kidney injury

Solute Carrier Family 22 (Organic Anion/urate Transporter), Member 12 (SLC22A12) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SLC22A12

  • solute carrier family 22 (organic anion/cation transporter), member 12 (Slc22a12) antibody
  • solute carrier family 22 (organic anion/urate transporter), member 12 (SLC22A12) antibody
  • solute carrier family 22 (organic anion/urate transporter), member 12 (Slc22a12) antibody
  • AI987855 antibody
  • OAT4L antibody
  • RST antibody
  • Slc22al2 antibody
  • URAT1 antibody

Protein level used designations for SLC22A12

renal-specific transporter , solute carrier family 22 (organic cation transporter)-like 2 , solute carrier family 22 member 12 , urate anion exchanger 1 , organic anion transporter 4-like protein , solute carrier family 22 (organic anion/cation transporter), member 12 , urate transporter 1

GENE ID SPECIES
20521 Mus musculus
116085 Homo sapiens
365398 Rattus norvegicus
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