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Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Additionally we are shipping Solute Carrier Family 24 Member 3 Antibodies (33) and many more products for this protein.
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NCKX3 is abundantly expressed within the human endometrium at the transcriptional and translational levels, and its level is regulated by steroid hormones (particularly estradiol) during the human menstrual cycle.
Plasma membrane ion transporter.Displayed K(+)-dependent Na(+)/Ca(2 (show CA2 Proteins)+) exchanger activity when assayed in heterologous expression systems, using digital imaging of fura-2 fluorescence, electrophysiology, or radioactive (45)Ca(2 (show CA2 Proteins)+) uptake.
The results of the present study indicate that NCKX3 is abundantly expressed in the uterus and that its expression is regulated by the steroid hormones E2 and P4.
Suggest that a high level of renal NCKX3 expression maintain in distal convoluted tubules may play a role in active calcium transport in the kidneys of female mice.
These results indicate that, for a proper MgATP up-regulation of NCX1 (show SLC8A1 Proteins), the enzyme responsible for PtdIns-4,5P2 synthesis must be (i) functionally competent and (ii) set in the NCX1 (show SLC8A1 Proteins) microenvironment closely associated to the exchanger.
The cleavage of NCX1 (show SLC8A1 Proteins) by m-calpain (show CAPN2 Proteins) in the caveolae vesicles may be interpreted as an important mechanism of Ca(2 (show CA2 Proteins)+) overload
a novel mechanism for the regulation of NCX1 (show SLC8A1 Proteins) activity
Na/Ca exchanger's (NCX1 (show SLC8A1 Proteins)) associates specifically with caveolin-3 (show CAV3 Proteins)(NCX1 (show SLC8A1 Proteins))(caveolin-3 (show CAV3 Proteins))
the regulation of phosphatidylinositol-4,5-biphosphate binding to the bovine cardiac Na+/Ca2+ exchanger(NCX1 (show SLC8A1 Proteins))
Data suggest that peroxynitrite leads to calcium (Ca2 (show CA2 Proteins)+) uptake through stimulation of Ca2+-ATPase, but inhibits Ca2 (show CA2 Proteins)+ uptake through inhibition of the sodium-Ca2 (show CA2 Proteins)+ exchanger, resulting in decreased overall Ca2 (show CA2 Proteins)+ uptake in smooth muscle microsomes.
These data suggest a role for the reverse mode of the NCX (show SLC8A1 Proteins) in refilling the sarcoplasmic reticulum in airway smooth muscle following Ca(2 (show CA2 Proteins)+) mobilization.
Cleavage of NCX (show SLC8A1 Proteins) may be interpreted as the main cause of Ca(2 (show CA2 Proteins)+) overload and could lay a key role in activation of apoptotic processes in pulmonary smooth muscle.
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001
Na(+)/K(+)/Ca(2+)-exchange protein 3
, sodium calcium exchanger
, sodium/potassium/calcium exchanger 3
, solute carrier family 24 member 3
, potassium-dependent sodium-calcium exchanger NCKX3 (SLC24A3)
, solute carrier family 24, member 3
, Na(+)/Ca(2+)-exchange protein 1
, sodium-calcium exchanger
, sodium/calcium exchanger 1
, solute carrier family 8, member 1