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Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Proteins (SLC25A20)

SLC25A20 product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. Additionally we are shipping Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Antibodies (55) and Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SLC25A20 SLC25A20 117035  
SLC25A20 788 O43772
SLC25A20 57279 Q9Z2Z6
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Top Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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SLC25A20 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Interaction Partners

Fruit Fly (Drosophila melanogaster) Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) interaction partners

  1. CalpA targets free Cactus, which is incorporated into and modulates Toll (show TLR4 Proteins)-responsive complexes in the embryo and immune system.

  2. Dorsal and Cactus maybe necessary for normal function and maintenance of the neuromuscular system. These proteins can respond to synaptic activity.

  3. Cactus acts as an inhibitor of the Rel-transcription factors Dorsal and Dif (show TNF Proteins).

  4. immune-induced degradation does not require CSN5 (show COPS5 Proteins)

  5. Dpp signals increase Cactus levels through Calpain A inhibition, thereby interfering with Dorsal activation

Human Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) interaction partners

  1. The antiport mode of transport, typical of mitochondrial carriers such as CAC (show CA2 Proteins), results from coupling of uniport reactions in opposite directions mediated by specific amino acid residues.

  2. C.576G>A, c.106-2a>t and c.516T>C are novel CACT gene mutations.

  3. CPT2 (show CPT2 Proteins) and CACT are crucial for mitochondrial acylcarnitine formation and export to the extracellular fluids in mitochondrial fatty acid beta-oxidation disorders.

  4. Compares and contrasts all the known human SLC25A (show SLC25A25 Proteins)* genes and includes functional information.

  5. Results show Steroid Receptor Coactivator (show SRA1 Proteins)-3 (SRC-3 (show NCOA3 Proteins)) plays a central role in long chain fatty acid metabolism by directly regulating carnitine/acyl-carnitine translocase (CACT) gene expression.

  6. These results show that FOXA and Sp1 (show PSG1 Proteins) sites in HepG2 cells and only the Sp1 (show PSG1 Proteins) site in HEK293 and SK-N-SH cells have a critical role in the transcriptional regulation of the CAC (show CA2 Proteins) proximal promoter.

  7. A deficiency in CACT was treated with a carnitine diet and administration of medium-chain triglycerides.

  8. The clinical, biochemical, & molecular features of 6 CACT-deficient patients from Italy, Spain, & North America who had significant clinical heterogeneity are reported. 5 novel & 3 previously reported mutations were found.

  9. The modulation of CACT expression has consequences for CPT 1 (show CPT1A Proteins) activity, while the biologic effects of acetyl-carnitine are not associated with a generic supply of energy compounds but to the anaplerotic property of the molecule.

  10. Report the outcome of two siblings with CACT deficiency.

Mouse (Murine) Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) interaction partners

  1. the 50-flanking region of the Cact gene contains a consensus sequence for ERRalpha (show ESRRA Proteins). This sequence binds ERRa (show ESRRA Proteins) both in vivo and in vitro and is required for the activation of Cact expression by the PGC-1/ERR (show SLC7A1 Proteins) axis

  2. Data show that the upregulation of CACT by PPARalpha (show PPARA Proteins) and PPARdelta (show PPARD Proteins) may increase the import of acylcarnitine into the mitochondrial matrix during fasting.

Solute Carrier Family 25 (Carnitine/acylcarnitine Translocase), Member 20 (SLC25A20) Protein Profile

Protein Summary

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

Gene names and symbols associated with SLC25A20

  • cactus (cact)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (slc25a20)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (SLC25A20)
  • carnitine/acylcarnitine translocase (LOC100352079)
  • solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 (Slc25a20)
  • protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A)
  • solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 (Slc25a20)
  • 5848 protein
  • 1110007P09Rik protein
  • BG:DS02740.15 protein
  • C78826 protein
  • CAC protein
  • cact protein
  • CG5848 protein
  • dif-1 protein
  • dip6 protein
  • DKFZp468F1219 protein
  • Dmel\\CG5848 protein
  • fs(2)ltoRN48 protein
  • mCAC protein
  • n(2)k17003 protein
  • PRKAR2A protein
  • SLC25A20 protein
  • zgc:77760 protein

Protein level used designations for SLC25A20

CG5848-PA , CG5848-PB , CG5848-PC , CG5848-PD , CG5848-PE , NF-kappa-B inhibitor cactus , cact-PA , cact-PB , cact-PC , cact-PD , cact-PE , female-sterile-(2)-ltoRN48 , solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 , carnitine/acylcarnitine translocase , CAC , mitochondrial carnitine/acylcarnitine carrier protein , solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 , solute carrier family 25 member 20 , protein kinase, cAMP-dependent, regulatory, type II, alpha , carnitine/acylcarnitine carrier protein , mitochondrial carnitine-acylcarnitine translocase

GENE ID SPECIES
34969 Drosophila melanogaster
779503 Xenopus (Silurana) tropicalis
460354 Pan troglodytes
709029 Macaca mulatta
100147786 Ovis aries
100173532 Pongo abelii
100352079 Oryctolagus cuniculus
117035 Rattus norvegicus
393833 Danio rerio
380111 Xenopus laevis
416062 Gallus gallus
788 Homo sapiens
484774 Canis lupus familiaris
518758 Bos taurus
57279 Mus musculus
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