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Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 Proteins (SLC25A5)

SLC25A5 is a member of the mitochondrial carrier subfamily of solute carrier protein genes. Additionally we are shipping SLC25A5 Kits (19) and SLC25A5 Antibodies (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC25A5 11740 P51881
SLC25A5 292 P05141
SLC25A5 25176 Q09073
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Top SLC25A5 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SLC25A5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , ,
,
Rat (Rattus)

More Proteins for Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) Interaction Partners

Mouse (Murine) Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) interaction partners

  1. Deficiency in the mouse mitochondrial ANT2 gene is associated with cardiac noncompaction.

  2. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  3. Erythroid and B-cell development may be particularly vulnerable to Ant2 depletion-mediated mitochondrial dysfunction and oxidative stress.

  4. Sirt4 (show SIRT4 Proteins) regulates ATP levels via ANT2 and a feedback loop involving AMPK (show PRKAA1 Proteins).

  5. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

  6. ANT2 and ANT1 (show SLC25A4 Proteins) regulate L1-mediated neurite outgrowth in conjunction with MMP14 (show MMP14 Proteins) at the plasma membrane.

  7. In liver only Ant2 mRNA was found, but in brown adipose tissue, Ant1 & Ant2 mRNA levels were equal. The ANT2 isoform may mediate fatty-acid-induced uncoupling.

  8. At high protonmotive force, an endogenously generated activator stimulates proton conductance catalysed partly by UCP3 and partly by the adenine nucleotide translocase.

Human Solute Carrier Family 25 (Mitochondrial Carrier, Adenine Nucleotide Translocator), Member 5 (SLC25A5) interaction partners

  1. ANT2 shRNA downregulates miR (show MLXIP Proteins)-19a and miR (show MLXIP Proteins)-96 through the PI3K (show PIK3CA Proteins)/Akt (show AKT1 Proteins) pathway and suppresses tumor growth in hepatocellular carcinoma cells.

  2. IFNgamma induces oxidative stress, DNA damage and tumor cell senescence via TGFbeta/SMAD signaling-dependent induction of Nox4 and suppression of ANT2

  3. TGF-beta (show TGFB1 Proteins)-mediated suppression of ANT2 through NF1 (show NF1 Proteins)/Smad4 (show SMAD4 Proteins) complexes contributes to oxidative stress and DNA damage during induction of cellular senescence.

  4. Sirt4 (show SIRT4 Proteins) regulates ATP levels via ANT2 and a feedback loop involving AMPK (show PRKAA1 Proteins).

  5. ANT2 suppression by shRNA may be able to exert anticancer effects in HCC (show FAM126A Proteins) further by restoring SOCS1 (show SOCS1 Proteins) expression

  6. SLC25A5 is involved in memory formation or establishment, which could add mitochondrial processes to the wide array of pathways that regulate normal cognitive functions.

  7. miR (show MLXIP Proteins)-636 might function as a tumor suppressor miRNA affecting hepatocellular carcinoma (HCC (show FAM126A Proteins)) tumorigenesis via downregulation of Ras, and that ANT2 suppression by shRNA could exert an anticancer effect by restoring miR (show MLXIP Proteins)-636 expression in HCC (show FAM126A Proteins).

  8. Apigenin upregulates DR5 and enhances TRAIL induced apoptosis by binding and inhibiting ANT2.

  9. Compares and contrasts all the known human SLC25A (show SLC25A25 Proteins)* genes and includes functional information.

  10. The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly.

SLC25A5 Protein Profile

Protein Summary

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.

Gene names and symbols associated with SLC25A5

  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (slc25a5)
  • adenine nucleotide translocator 2 (LOC100158185)
  • adenine nucleotide translocator 2 (LOC100301662)
  • solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 (Slc25a5)
  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (SLC25A5)
  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 (Slc25a5)
  • 2F1 protein
  • AAC2 protein
  • ANT2 protein
  • T2 protein
  • T3 protein

Protein level used designations for SLC25A5

adenine nucleotide translocator 2 , ADP,ATP carrier protein 2 , ADP/ATP translocase 2 , ANT 2 , adenine nucleotide translocase , adenine nucleotide translocator 2, fibroblast , solute carrier family 25 member 5 , ADP,ATP carrier protein, fibroblast isoform , ADP/ATP carrier protein , adenine nucleotide translocator 2 (fibroblast) , Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein) , Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein) , adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein) , adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein)

GENE ID SPECIES
380187 Xenopus laevis
100158185 Sus scrofa
100301662 Oncorhynchus mykiss
11740 Mus musculus
292 Homo sapiens
25176 Rattus norvegicus
282479 Bos taurus
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