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Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19) ELISA Kits

SLC25A19 encodes a mitochondrial protein that is a member of the solute carrier family. Additionally we are shipping Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 Antibodies (26) and Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat SLC25A19 SLC25A19 303676  
Anti-Mouse SLC25A19 SLC25A19 67283 Q9DAM5
Anti-Human SLC25A19 SLC25A19 60386 Q9HC21
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More ELISA Kits for Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 Interaction Partners

Mouse (Murine) Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19) interaction partners

  1. Chronic alcohol exposure negatively impacts pancreatic mitochondrial thiamin pyrophosphate transport, and this effect is exerted, at least in part, at the level of Slc25a19 transcription and appears to involve an epigenetic mechanism.

  2. mitochondria of Slc25a19(-/-) and Amish lethal microcephaly cells have undetectable and markedly reduced thiamine pyrophosphate content, respectively

  3. We review the evidence that the function of the SLC25A19 gene product, previously identified as the mitochondrial deoxyribonucleotide carrier (DNC), is actually the transport of thiamine pyrophosphate.[review]

Human Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19) interaction partners

  1. Chronic alcohol exposure negatively impacts pancreatic mitochondrial thiamin pyrophosphate transport, and this effect is exerted, at least in part, at the level of Slc25a19 transcription and appears to involve an epigenetic mechanism.

  2. These findings demonstrate that the genes involved in dictating thiamine homeostasis, such as SLC19A2, SLC25A19 and TPK-1, were significantly up-regulated in clinical tissues and breast cancer cell lines.

  3. Characterization of the SLC25A19 promoter and demonstration of an essential role for NF-Y in its basal activity.

  4. Compares and contrasts all the known human SLC25A (show SLC25A25 ELISA Kits)* genes and includes functional information.

  5. mutant protein lacks the normal transport activity, implying that failed deoxynucleotide transport across the inner mitochondrial membrane causes Amiah microcephaly (MCPHA)

  6. mitochondria of Slc25a19(-/-) and Amish lethal microcephaly cells have undetectable and markedly reduced thiamine pyrophosphate content, respectively

  7. We review the evidence that the function of the SLC25A19 gene product, previously identified as the mitochondrial deoxyribonucleotide carrier (DNC), is actually the transport of thiamine pyrophosphate.[review]

  8. a pathogenic missense mutation in the SLC25A19 gene was identifiedin 4 patients who suffered from recurrent episodes of flaccid paralysis and encephalopathy associated with bilateral striatal necrosis and chronic progressive polyneuropathy

Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19) Antigen Profile

Antigen Summary

This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Gene names and symbols associated with SLC25A19

  • solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 (Slc25a19) antibody
  • solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 (slc25a19) antibody
  • solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 (SLC25A19) antibody
  • 2900089E13Rik antibody
  • DNC antibody
  • MCPHA antibody
  • MUP1 antibody
  • THMD3 antibody
  • THMD4 antibody
  • TPC antibody
  • zgc:111878 antibody

Protein level used designations for SLC25A19

mitochondrial thiamine pyrophosphate carrier , solute carrier family 25, member 19 , solute carrier family 25 (mitochondrial deoxynucleotide carrier), member 19 , solute carrier family 25 member 19 , solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 , microcephaly, Amish , mitochondrial uncoupling protein 1 , mitochondrial deoxynucleotide carrier , Mitochondrial deoxynucleotide carrier

GENE ID SPECIES
303676 Rattus norvegicus
403024 Danio rerio
422123 Gallus gallus
454879 Pan troglodytes
483311 Canis lupus familiaris
548707 Xenopus (Silurana) tropicalis
706122 Macaca mulatta
100217405 Ovis aries
100302700 Sus scrofa
100582800 Nomascus leucogenys
67283 Mus musculus
60386 Homo sapiens
504418 Bos taurus
100174169 Pongo abelii
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