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Solute Carrier Family 26, Member 6 (SLC26A6) ELISA Kits

SLC26A6 belongs to the solute carrier 26 family, whose members encode anion transporter proteins. Additionally we are shipping SLC26A6 Antibodies (24) and SLC26A6 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat SLC26A6 SLC26A6 301010  
Anti-Human SLC26A6 SLC26A6 65010 Q9BXS9
Anti-Mouse SLC26A6 SLC26A6 171429  
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More ELISA Kits for SLC26A6 Interaction Partners

Zebrafish Solute Carrier Family 26, Member 6 (SLC26A6) interaction partners

Human Solute Carrier Family 26, Member 6 (SLC26A6) interaction partners

  1. Molecular dynamics simulations of the STAS domains of rat prestin (show SLC26A5 ELISA Kits) and human pendrin (show SLC26A4 ELISA Kits) reveal conformational motions in conserved flexible regions.

  2. Data show that SLC26A6 variants do not alter the risk for the development of chronic pancreatitis.

  3. In the intestinal epithelium, PAT-1 (show APPBP2 ELISA Kits) (SLC26A6) could mediate apical oxalate influx or apical oxalate efflux depending on the magnitude and direction prevailing counterion driver gradients as well as the relative affinities of the transported anions.

  4. orthologous mouse and human SLC26A6 proteins differ in anion selectivity, transport mechanism, and acute regulation, but both mediate electroneutral Cl(-)/HCO(3)(-) exchange

  5. In human kidney SLC26A6 and A7 have a distinct, partially overlapping expression in distal segments of nephrons. The distribution partly differs from that found previously in rodent kidneys.

  6. findings indicate that slc26a6 functions as a coupled 1Cl-/2HCO3- exchanger

  7. Mouse Slc26a6 and human SLC26A6 each mediated electroneutral Cl-/HCO3- and Cl-/OH- exchange. But, whereas Cl-/oxalate exchange by mouse Slc26a6 was electrogenic, that mediated by human SLC26A6 appeared electroneutral.

  8. No mutation was found in the coding regions and intron-exon boundaries of the genes for CA II (show CA2 ELISA Kits), CA IV (show CA4 ELISA Kits), CA XIV (show CA14 ELISA Kits), kNCB1, NHE3 (show SLC9A3 ELISA Kits), NHE8 (show SLC9A8 ELISA Kits), NHRF1, NHRF2 and SLC26A6 amplified from genomic DNA of family members with pRTA.

  9. Low extracellular Cl(-) affinity and electroneutrality of oxalate efflux characterizing human SLC26A6 explain the high human susceptibility to nephrolithiasis relative to mice. SLC26A6 sequence variant(s) are candidate risk modifiers for nephrolithiasis.

  10. involvement of IRF-1 (show IRF1 ELISA Kits) in the regulation of SLC26A6 gene expression by IFNgamma in the human intestine

Mouse (Murine) Solute Carrier Family 26, Member 6 (SLC26A6) interaction partners

  1. Slc26a1 (show SLC26A1 ELISA Kits), Slc26a6 and Slc26a7 (show SLC26A7 ELISA Kits) are novel participants in the extracellular transport of bicarbonate during enamel maturation.

  2. Results suggest that PAT1 (show APPBP2 ELISA Kits) slows down APP (show APP ELISA Kits) trafficking to the cell surface in primary cortical neurons

  3. Both PAT-1 and DRA significantly contribute to intestinal fluid absorption and enterocyte acid/base balance but are activated by different ion gradients.

  4. Cardiac myocytes express different isoforms of Slc26a6, which encode electrogenic Cl(-)/HCO3(-) and Cl(-)/oxalate exchangers.

  5. Slc26a6-null mice exhibited increased renal and intestinal sodium-dependent succinate uptake, as well as urinary hyperoxaluria and hypocitraturia, but no change in urinary pH, indicating enhanced transport activity of NaDC-1 (show SLC13A2 ELISA Kits).

  6. NMR and CE were used to characterize the urinary metabolome in slc26a6 null mice. Clear metabolic differentiation between the urinary profiles of the slc26a6 null and the wild type mice were observed using both methods.

  7. SLC26A6 mediates 1:2 Cl-/HCO3- exchange, and the exchanger most probably upregulates SLC26A3 (show SLC26A3 ELISA Kits) in its absence, therefore mediating 2:1 exchange.

  8. Data demonstrate functional Pat-1 Cl)/HCO3) exchange activity in the lower villus epithelium of the murine duodenum which, in previous studies, had been obscured by the inclusion of luminal glucose as a metabolic substrate.

  9. This study showed a functionally active CFTR (show CFTR ELISA Kits) is an absolute requirement for Slc26-mediated duodenal bicarbonate secretion, but not for Slc26-mediated fluid absorption.

  10. study concludes Pat-1 Cl(-)/HCO(3)(-) exchange contributes to pH(i) regulation in the duodenal villous epithelium during H(+)-dipeptide absorption, possibly by providing a HCO(3)(-) import pathway

SLC26A6 Antigen Profile

Antigen Summary

This gene belongs to the solute carrier 26 family, whose members encode anion transporter proteins. This particular family member encodes a protein involved in transporting chloride, oxalate, sulfate and bicarbonate. Several alternatively spliced transcript variants of this gene, encoding distinct isoforms, have been described, but the full-length nature of some of these variants has not been determined.

Gene names and symbols associated with SLC26A6

  • solute carrier family 26 (anion exchanger), member 6 (Slc26a6) antibody
  • solute carrier family 26, member 6 (SLC26A6) antibody
  • solute carrier family 26, member 6 (slc26a6) antibody
  • solute carrier family 26, member 6, like (slc26a6l) antibody
  • solute carrier family 26 (anion exchanger), member 6 (SLC26A6) antibody
  • solute carrier family 26, member 6 (Slc26a6) antibody
  • B930010B04Rik antibody
  • CFEX antibody
  • MGC81960 antibody
  • MGC145603 antibody
  • Pat1 antibody
  • si:dkey-20d21.8 antibody
  • slc26a6 antibody
  • zgc:175226 antibody

Protein level used designations for SLC26A6

solute carrier family 26, member 6 , solute carrier family 26 member 6 , SLC26A6a anion exchanger , slc26a6c , slc26a6b , anion transporter 1 , pendrin L1 , sulfate anion transporter

GENE ID SPECIES
301010 Rattus norvegicus
416012 Gallus gallus
444778 Xenopus laevis
497236 Sus scrofa
514514 Bos taurus
559448 Danio rerio
608998 Canis lupus familiaris
780378 Xenopus (Silurana) tropicalis
100005108 Danio rerio
100173317 Pongo abelii
100613198 Pan troglodytes
65010 Homo sapiens
171429 Mus musculus
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