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Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. Additionally we are shipping Solute Carrier Family 28 (Sodium-Coupled Nucleoside Transporter), Member 3 Antibodies (9) and many more products for this protein.
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CYR61 (show CYR61 Proteins) negatively regulates the nucleoside transporters hENT1 and hCNT3 in pancreatic ductal adenocarcinoma.
Data suggest that CNT3 forms a homotrimer in solution and membrane-bound inside cells; the quaternary structure creates an aqueous basin that significantly shortens the substrate translocation distance.
results that validate the newly developed structural homology model of CNT membrane architecture for human CNTs, revealed extended conformationally mobile regions within transport-domain TMs (show TYMS Proteins), identified pore-lining residues of functional importance, and provided evidence of an emerging novel elevator-type mechanism of transporter function.
Genome-wide association analysis on normal hearing function identifies PCDH20 (show PCDH20 Proteins) and SLC28A3 as good candidates for modulatory genes in the auditory system. [meta-analysis]
The co-expression of galectin-4 (show LGALS4 Proteins) and CNT3 proteins is not impaired in inflamed colon from patients with Crohn's disease, thereby anticipating the integrity of this system for drug targeting.
Results show that high CNT3 expression level is associated with overall favorable outcomes and is predictive of clinical outcomes in acute myeloid leukemia (show BCL11A Proteins) patients with t(8;21).
The presence of homozygous major allele for SLC28A3 (CC genotype) were each associated with an almost two-fold increase in the formation clearance of dFdCTP.
Genetic polymorphisms in SLC28A3, SLC29A1 (show SLC29A1 Proteins) and RRM1 (show RRM1 Proteins) can influence the clinical outcome of metastatic breast cancer patients treated with paclitaxel-gemcitabine chemotherapy.
association between ribavirin (RBV) serum levels and SLC28A2 (show SLC28A2 Proteins) rs11854484 genotype, as well as the replicated association of ITPA (show ITPA Proteins) and SLC28A3 genetic polymorphisms with RBV-induced anemia and treatment response
Validation of variants in SLC28A3 and UGT1A6 (show UGT1A6 Proteins) as genetic markers predictive of anthracycline-induced cardiotoxicity in children.
Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001
concentrative Na(+)-nucleoside cotransporter 3
, concentrative Na+-nucleoside cotransporter
, solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
, solute carrier family 28 member 3
, CNT 3