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SLC29A1 is a member of the equilibrative nucleoside transporter family. Additionally we are shipping SLC29A1 Kits (4) and SLC29A1 Proteins (4) and many more products for this protein.
Showing 10 out of 156 products:
Human Polyclonal SLC29A1 Primary Antibody for WB - ABIN387940
Ibarra, Pfeiffer: Reduced ribavirin antiviral efficacy via nucleoside transporter-mediated drug resistance. in Journal of virology 2009
Show all 3 references for ABIN387940
Human Polyclonal SLC29A1 Primary Antibody for EIA - ABIN358541
Bone, Robillard, Stolk, Hammond: Differential regulation of mouse equilibrative nucleoside transporter 1 (mENT1) splice variants by protein kinase CK2. in Molecular membrane biology 2007
Show all 2 references for ABIN358541
Human Polyclonal SLC29A1 Primary Antibody for EIA, IHC (p) - ABIN4620415
Abdulla, Coe: Characterization and functional analysis of the promoter for the human equilibrative nucleoside transporter gene, hENT1. in Nucleosides, nucleotides & nucleic acids 2006
Show all 2 references for ABIN4620415
Human Polyclonal SLC29A1 Primary Antibody for DB - ABIN389998
Dephoure, Zhou, Villén, Beausoleil, Bakalarski, Elledge, Gygi: A quantitative atlas of mitotic phosphorylation. in Proceedings of the National Academy of Sciences of the United States of America 2008
Human ENT1 proteins exist as two sub-populations, and cytidine pre-treatment leads to the internalization of one population.
Results showed that both SLC29A1 and SLC29A2 (show SLC29A2 Antibodies) were expressed at lower levels in colon cancer cell lines originating from metastatic sites than from primary sites.
Direct evidence for apical localization of ENT1 and integral expression of ENT2 (show SLC29A2 Antibodies) in intestinal epithelial cells.
mRNA expression of ENT1 was closely associated with cell proliferation and varied in seven non-Hodgkin lymphoma cell lines.
Low ENT1 expression is associated with periampullary adenocarcinoma.
Studies indicate that an autophagy response induced by hepatitis C virus (HCV) in a cell culture reduces ribavirin (RBV) uptake and antiviral activity by diminishing the surface expression of nucleoside transporters) member 1 (ENT1).
The identification of ITPA (show ITPA Antibodies) protective and SLC29A1 risk genotypes still appears to be a current methodology in Ribavirin dosing during hepatitis C virus therapy with direct acting antiviral agents
RNA expression of deoxycytidine kinase (DCK (show DCK Antibodies)), human equilibrative nucleoside transporter-1 (ENT1) and ribonucleotide reductase M1 (RRM1 (show RRM1 Antibodies)) were significantly higher and cytidine deaminase (CDA (show CDA Antibodies)) was significantly lower in ex vivo Ara (show FOXC1 Antibodies)-C sensitive samples.
RECPAM analysis showed that DCK (show DCK Antibodies) and CHOP (show DDIT3 Antibodies) were most relevant variables for the identification of patients with different mortality risk, while hENT1 and CHOP (show DDIT3 Antibodies) were able to identify subgroups of patients with different disease progression risk
ENT1 expression profile did not serve as a useful prognostic biomarker and therapeutic target for surgically resected patients with ampullary carcinoma.
results establish Augustine as a new blood group (show DARC Antibodies) system and place SLC29A1 as a new candidate gene for idiopathic disorders characterized with ectopic calcification/mineralization.
Findings demonstrate that ENT1 regulates GFAP (show GFAP Antibodies) expression and possibly astrocyte function
ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density
findings implicate ENT1 in liver protection from ischemia and reperfusion injury and suggest ENT inhibitors may be of benefit in the prevention or treatment of ischemic liver injury
This is the first report of a role for ENT1 in regulating the calcification of soft tissues. ENT1(-/-) mice may be a useful model for investigating pathogenesis and evaluating therapeutics for the prevention of mineralization in DISH and related disord
It was shown that the responsiveness of kidney tubules and glomeruli is significantly attenuated in the absence of ENT1, leading to changes of extracellular adenosine levels in the juxtaglomerular apparatus interstitium.
This study demonstrated that the A2AR (show ADORA2A Antibodies) antagonist ZM241385 dampened protein kinase A activity-mediated signaling in the DMS and promoted excessive ethanol drinking in ENT1(+/+) mice
Perfusions without sodium drastically reduced the intestinal loss of ribavirin in both wild-type and Ent1(-/-) mice.
These studies identify ENT1 and adenosine receptors as key to the process of reestablishing renal perfusion following ischemic acute kidney injury.
Mice lacking ENT1 exhibit increased glutamate (show GRIN1 Antibodies) levels in the nucleus accumbens as well as increased ethanol drinking behaviors.
This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
equilibrative NBMPR-sensitive nucleoside transporter
, equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter
, equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter
, equilibrative nucleoside transporter 1
, nucleoside transporter, es-type
, solute carrier family 29 (nucleoside transporters), member 1
, solute carrier family 29 member 1
, solute carrier family 29, member 1
, NBMPR-sensitive equilibrative nucleoside transporter
, equilibrative nucleoside transporter 1 variant delta 11