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Solute Carrier Family 29 (Nucleoside Transporters), Member 1 Proteins (SLC29A1)

SLC29A1 is a member of the equilibrative nucleoside transporter family. Additionally we are shipping SLC29A1 Antibodies (153) and SLC29A1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC29A1 2030 Q99808
Rat SLC29A1 SLC29A1 63997 O54698
SLC29A1 63959 Q9JIM1
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Top SLC29A1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SLC29A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced SLC29A1 Proteins

  1. Human SLC29A1 Protein expressed in Wheat germ - ABIN1320347 : Greenhalf, Ghaneh, Neoptolemos, Palmer, Cox, Lamb, Garner, Campbell, Mackey, Costello, Moore, Valle, McDonald, Carter, Tebbutt, Goldstein, Shannon, Dervenis, Glimelius, Deakin, Charnley, Lacaine et al.: Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial. ... in Journal of the National Cancer Institute 2014 (PubMed)

More Proteins for Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) Interaction Partners

Human Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. Studies indicate that an autophagy response induced by hepatitis C virus (HCV) in a cell culture reduces ribavirin (RBV) uptake and antiviral activity by diminishing the surface expression of nucleoside transporters) member 1 (ENT1).

  2. The identification of ITPA (show ITPA Proteins) protective and SLC29A1 risk genotypes still appears to be a current methodology in Ribavirin dosing during hepatitis C virus therapy with direct acting antiviral agents

  3. RNA expression of deoxycytidine kinase (DCK (show DCK Proteins)), human equilibrative nucleoside transporter-1 (ENT1) and ribonucleotide reductase M1 (RRM1 (show RRM1 Proteins)) were significantly higher and cytidine deaminase (CDA (show CDA Proteins)) was significantly lower in ex vivo Ara (show FOXC1 Proteins)-C sensitive samples.

  4. RECPAM analysis showed that DCK (show DCK Proteins) and CHOP (show DDIT3 Proteins) were most relevant variables for the identification of patients with different mortality risk, while hENT1 and CHOP (show DDIT3 Proteins) were able to identify subgroups of patients with different disease progression risk

  5. ENT1 expression profile did not serve as a useful prognostic biomarker and therapeutic target for surgically resected patients with ampullary carcinoma.

  6. Adenosine A1 receptor activation increases ENT1 activity via protein kinase C.

  7. Brains from patients with drug-resistant temporal lobe epilepsy had higher levels of ENT1 than controls.

  8. Acute myeloid leukemia (show BCL11A Proteins) patients with low activity of SLC29A1 genotype have shorter disease-free and overall survival in Ara (show FOXC1 Proteins)-C based therapy.

  9. SNPS in SLC29A1 were not associated with increased risk of post-traumatic epilepsy development after brain injury.

  10. results establish Augustine as a new blood group (show DARC Proteins) system and place SLC29A1 as a new candidate gene for idiopathic disorders characterized with ectopic calcification/mineralization.

Mouse (Murine) Solute Carrier Family 29 (Nucleoside Transporters), Member 1 (SLC29A1) interaction partners

  1. results establish Augustine as a new blood group (show DARC Proteins) system and place SLC29A1 as a new candidate gene for idiopathic disorders characterized with ectopic calcification/mineralization.

  2. Findings demonstrate that ENT1 regulates GFAP (show GFAP Proteins) expression and possibly astrocyte function

  3. ENT1-regulated adenosine signaling plays an essential role in lumbar spine and femur bone density

  4. findings implicate ENT1 in liver protection from ischemia and reperfusion injury and suggest ENT inhibitors may be of benefit in the prevention or treatment of ischemic liver injury

  5. This is the first report of a role for ENT1 in regulating the calcification of soft tissues. ENT1(-/-) mice may be a useful model for investigating pathogenesis and evaluating therapeutics for the prevention of mineralization in DISH and related disord

  6. It was shown that the responsiveness of kidney tubules and glomeruli is significantly attenuated in the absence of ENT1, leading to changes of extracellular adenosine levels in the juxtaglomerular apparatus interstitium.

  7. This study demonstrated that the A2AR (show ADORA2A Proteins) antagonist ZM241385 dampened protein kinase A activity-mediated signaling in the DMS and promoted excessive ethanol drinking in ENT1(+/+) mice

  8. Perfusions without sodium drastically reduced the intestinal loss of ribavirin in both wild-type and Ent1(-/-) mice.

  9. These studies identify ENT1 and adenosine receptors as key to the process of reestablishing renal perfusion following ischemic acute kidney injury.

  10. Mice lacking ENT1 exhibit increased glutamate (show GRIN1 Proteins) levels in the nucleus accumbens as well as increased ethanol drinking behaviors.

SLC29A1 Protein Profile

Protein Summary

This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.

Gene names and symbols associated with SLC29A1

  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (SLC29A1)
  • solute carrier family 29 (equilibrative nucleoside transporter), member 1 (Slc29a1)
  • solute carrier family 29 (nucleoside transporters), member 1 (Slc29a1)
  • 1200014D21Rik protein
  • AA407560 protein
  • ENT1 protein
  • rENT1 protein

Protein level used designations for SLC29A1

equilibrative NBMPR-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside (NBMPR)-sensitive nucleoside transporter , equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter , equilibrative nucleoside transporter 1 , nucleoside transporter, es-type , solute carrier family 29 (nucleoside transporters), member 1 , solute carrier family 29 member 1 , solute carrier family 29, member 1 , NBMPR-sensitive equilibrative nucleoside transporter , equilibrative nucleoside transporter 1 variant delta 11

GENE ID SPECIES
2030 Homo sapiens
63997 Rattus norvegicus
63959 Mus musculus
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