Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2) ELISA Kits

The protein encoded by SLC34A2 is a pH-sensitive sodium-dependent phosphate transporter. Additionally we are shipping SLC34A2 Antibodies (20) and SLC34A2 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC34A2 SLC34A2 20531 Q9DBP0
Anti-Human SLC34A2 SLC34A2 10568 O95436
Anti-Rat SLC34A2 SLC34A2 84395 Q9JJ09
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More ELISA Kits for SLC34A2 Interaction Partners

Pig (Porcine) Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2) interaction partners

  1. A sodium-dependent phosphate transporter gene, NaPi-IIb, was isolated from swine small intestine using cDNA library screening method.

Mouse (Murine) Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2) interaction partners

  1. This study validated the role of Npt2b in the pathogenesis of Pulmonary alveolar microlithiasis (PAM (show PAM ELISA Kits)).

  2. Overall, our preclinical results suggest that the ADC (show ADC ELISA Kits) targeting NaPi2b provides an effective new therapy for the treatment of NSCLC and ovarian cancer and is currently undergoing clinical developments.

  3. NaPi-IIb is the only luminal Na(+) -dependent Pi transporter in the murine ileum and its absence is fully compensated for in adult females by a mechanism involving the bone-kidney axis.

  4. Knockdown of the sodium-dependent phosphate co-transporter 2b (NPT2b) suppresses lung tumorigenesis.

  5. B-RAF (show SNRPE ELISA Kits) increases the cell surface protein (show CD28 ELISA Kits) abundance and activity of the type II Na+-coupled phosphate transporters NaPi-IIa (show SLC34A1 ELISA Kits) and NaPi-IIb.

  6. that NHERF1 (show SLC9A3R2 ELISA Kits) associates with NaPi-2b in enterocytes and regulates NaPi-2b adaptation.

  7. Compared with wild-type uremic mice, Npt2b-deficient uremic mice had significantly lower levels of serum phosphate and attenuation of FGF23 (show FGF23 ELISA Kits).

  8. Npt2b is an important target for the prevention of hyperphosphatemia

  9. In GABARAP (show GABARAP ELISA Kits)-deficient mice renal NaPi-IIa (show SLC34A1 ELISA Kits) is up-regulation and intestinal NaPi-IIb is downregulated.

  10. NaPi-IIb was the predominantly expressed epithelial isoform of the sodium-inorganic phosphate cotransporter and was markedly overexpressed in the proximal region in the infertile knockout compared to the fertile heterozygous c-ros (show ROS1 ELISA Kits) transgenic mouse

Human Solute Carrier Family 34 (Sodium Phosphate), Member 2 (SLC34A2) interaction partners

  1. High expression of SLC34A2 was identified in about 2/3 patients and correlated with significantly better patient's overall survival. Epidermal growth factor receptor (show EGFR ELISA Kits) mutations were detected in about 53% of patients with no statistically significant difference to patient's overall survival. Anaplastic lymphoma kinase (show ALK ELISA Kits) rearrangement was found in 8 out of 175 patients, harboring this abnormality leads to shorter overall survi

  2. we elucidated that miR (show MLXIP ELISA Kits)-939 exerted its function mainly through inhibiting SLC34A2/Raf (show RAF1 ELISA Kits)/MEK (show MAP2K1 ELISA Kits)/ERK (show EPHB2 ELISA Kits) pathway, which is activated in GC. Multivariate analysis identified miR (show MLXIP ELISA Kits)-939, SLC34A2, and their combination as independent indicators for poor prognosis and tumor recurrence in GC patients.

  3. a novel role of SLC34A2 inbreast cancer stem cells (BCSCs) state regulation and establishes a rationale for targeting the SLC34A2/PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits)/SOX2 (show SOX2 ELISA Kits) signaling pathway for breast cancer therapy.

  4. Knockdown of SLC34A2 inhibits proliferation.

  5. our work indicated that decreased SLC34A2 expression sensitized BCSCs to doxorubicin via SLC34A2-Bmi1 (show BMI1 ELISA Kits)-ABCC5 (show ABCC5 ELISA Kits) signaling and shed new light on understanding the mechanism of chemoresistance in BCSCs. This study not only bridges the missing link between stem cell-related transcription factor (Bmi1 (show BMI1 ELISA Kits)) and ABC transporter (show ABCG2 ELISA Kits) (ABCC5 (show ABCC5 ELISA Kits)) but also contributes to development of potential therapeutics against breast cancer.

  6. Our work sheds new light on the nature of the state of lung cancer stem cell-like cells and the role of SLC34A2 in the tumorigenicity of these cells

  7. SPAK (show STK39 ELISA Kits) and OSR1 (show OXSR1 ELISA Kits) are powerful stimulators of the intestinal Na+-coupled phosphate co-transporter NaPi-IIb

  8. our data indicated that SLC34A2 could exert significantly suppressive effects on tumorigenesis and progression of NSCLC. SLC34A2 might provide new insights for further understanding the early pathogenesis of human non-small cell lung cancer

  9. SLC34A2 might be associated with the initiation and progression of lung adenocarcinoma

  10. Data indicate that humanized monoclonal antibody Rebmab200 and murine monoclonal antibody MX35 monoclonal antibodies had similar specificity for sodium phosphate transporter (show SLC17A1 ELISA Kits) NaPi2b.

SLC34A2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. Phosphate uptake is increased at lower pH. Defects in this gene are a cause of pulmonary alveolar microlithiasis. Three transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with SLC34A2

  • solute carrier family 34 (sodium phosphate), member 2 (SLC34A2) antibody
  • solute carrier family 34 (sodium phosphate), member 2 (Slc34a2) antibody
  • solute carrier family 34 (type II sodium/phosphate contransporter), member 2 (SLC34A2) antibody
  • solute carrier family 34 (type II sodium/phosphate contransporter), member 2 (Slc34a2) antibody
  • AA536683 antibody
  • D5Ertd227e antibody
  • NaPi-2b antibody
  • NAPI-3B antibody
  • NAPI-IIb antibody
  • Npt2b antibody
  • NPTIIb antibody
  • SLC34A2 antibody

Protein level used designations for SLC34A2

Na/Pi cotransporter NaPi-IIb , sodium-dependent phosphate transport protein 2B , type IIb sodium phosphate cotransporter , solute carrier family 34 (sodium phosphate), member 2 , sodium-dependent phosphate cotransporter isoform NaPi-IIb , Na(+)-dependent phosphate cotransporter 2B , Na(+)/Pi cotransporter 2B , sodium-phosphate transport protein 2B , sodium/phosphate cotransporter 2B , solute carrier family 34 member 2 , type IIb Na/Picotransporter , naPi-2b , type II sodium-dependent phosphate transporter 3b , rNaPi IIb , type IIb sodium-phosphate transporter

395131 Gallus gallus
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641347 Sus scrofa
694217 Macaca mulatta
20531 Mus musculus
282484 Bos taurus
100171622 Pongo abelii
10568 Homo sapiens
84395 Rattus norvegicus
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