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Solute Carrier Family 36 (Proton/amino Acid Symporter), Member 1 (SLC36A1) ELISA Kits

SLC36A1 encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. Additionally we are shipping SLC36A1 Antibodies (25) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC36A1 SLC36A1 206358 Q7Z2H8
Anti-Mouse SLC36A1 SLC36A1 215335 Q8K4D3
Anti-Rat SLC36A1 SLC36A1 155205 Q924A5
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More ELISA Kits for SLC36A1 Interaction Partners

Human Solute Carrier Family 36 (Proton/amino Acid Symporter), Member 1 (SLC36A1) interaction partners

  1. Sertraline is an apparent non-competitive inhibitor of PAT1-mediated transport.

  2. Data suggest that PAT1 in enterocytes is responsible for intestinal absorption of some of the alkaloids from areca nut (i.e., arecaidine, guvacine, isoguvacine).

  3. estrogen attenuates the activity of PAT1 by directly closing PAT1

  4. In hPAT1 expressing oocytes Gly-Tyr (show TYR ELISA Kits), Gly-Pro, and Gly-Phe inhibited currents induced by drug substances.

  5. In human cells, SLC36A1 localized on intracellular membranes is required for amino acid-dependent mTORC1 activation and cell proliferation. SLC36A1 also has similar in vivo growth regulatory activity to fly SLC36 AAAPs when expressed in Drosophila.

  6. PAT1 expressed exclusively in apical membrane of Caco-2 cells. hPAT1 may be responsible for H(+)-coupled amino acid transport expressed in apical membrane of Caco-2 cells.

  7. Amino acid uptake via hPAT1 is inhibited by activators of the cAMP pathway indirectly through inhibition of NHE3 (show SLC9A3 ELISA Kits) activity.

  8. PAT1a, which is 99.0% identical to protein interacting with APP tail 1 (PAT1 (show APPBP2 ELISA Kits)), is a functional link between the transport and processing of beta-amyloid precursor protein APP and its two paralogs APLP1 (show APLP1 ELISA Kits) and APLP2 (show APLP2 ELISA Kits) in vivo.

  9. His-55 might be responsible for binding and translocation of H+ in the course of cellular amino acid uptake by PAT1.

  10. This study is the first to demonstrate both taurine uptake via PAT1 and functional expression of PAT1 at the apical membrane of the intestinal epithelium.

Mouse (Murine) Solute Carrier Family 36 (Proton/amino Acid Symporter), Member 1 (SLC36A1) interaction partners

  1. Data suggest that a high-fat diet induces expression of two amino acid transporters (Slc36a1, Slc6a20a) in intestinal mucosa pointing to a specific and adaptive absorption of some amino acids in high-fat diet-induced obesity and glucose intolerance.

  2. detailed analysis of the transport mode of the murine PAT1 in oocytes; PAT1 is an electrogenic H+-coupled amino acid symporter with the capability for bidirectional amino acid transport

  3. The essential role of chloride and fructose absorbing Slc36a1 is reported.

SLC36A1 Antigen Profile

Antigen Summary

This gene encodes a member of the eukaryote-specific amino acid/auxin permease (AAAP) 1 transporter family. The encoded protein functions as a proton-dependent, small amino acid transporter. This gene is clustered with related family members on chromosome 5q33.1.

Gene names and symbols associated with SLC36A1

  • solute carrier family 36 (proton/amino acid symporter), member 1 (SLC36A1) antibody
  • solute carrier family 36 (proton/amino acid symporter), member 1 (Slc36a1) antibody
  • 5830411H19Rik antibody
  • AI839897 antibody
  • Dct1 antibody
  • Lyaat1 antibody
  • Pat1 antibody
  • TRAMD3 antibody

Protein level used designations for SLC36A1

hPAT1 , lysosomal amino acid transporter 1 , proton-coupled amino acid transporter 1 , proton/amino acid transporter 1 , solute carrier family 36 member 1 , LYAAT-1 , neutral amino acid/proton symporter , ysosomal amino acid transporter 1

GENE ID SPECIES
206358 Homo sapiens
215335 Mus musculus
155205 Rattus norvegicus
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