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Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14) ELISA Kits

Zinc is an essential cofactor for hundreds of enzymes. Additionally we are shipping SLC39A14 Antibodies (50) and SLC39A14 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC39A14 SLC39A14 23516 Q15043
Anti-Mouse SLC39A14 SLC39A14 213053 Q75N73
Anti-Rat SLC39A14 SLC39A14 306009  
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More ELISA Kits for SLC39A14 Interaction Partners

Human Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14) interaction partners

  1. Polymorphisms in SLC39A14 and SLC39A8 (show SLC39A8 ELISA Kits) seemed to affect blood cadmium concentrations, for SLC39A14 this effect may occur via differential gene expression.

  2. These results suggest that both the up-regulation of ZIP14 and the down-regulation of ZnT10 by IL-6 (show IL6 ELISA Kits) might have enhanced the accumulation of manganese in SH-SY5Y cells.

  3. Asparagine-linked (N-linked) glycosylation of ZIP14, particularly the glycosylation at N102, was required for efficient membrane extraction of ZIP14 and therefore is necessary for its iron sensitivity.

  4. Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response

  5. Data show the role of ZIP14 in the hepatocyte is multi-functional since zinc and iron trafficking are altered in the Zip14(-/-) mice and their phenotype shows defects in glucose homeostasis.

  6. the SLC39A14-exon4B transcript variant is a colorectal cancer biomarker with high sensitivity and organ-confined specificity.

  7. Data suggest that Zip-14 mRNA level in enterocytes increases with iron or zinc depletion; Zip-14 transcript level in enterocytes decreases with zinc supplementation.

  8. Observations indicate that ZIP14 and ZIP8 are both broad-scope metal-ion transporters that can mediate the cellular uptake of nutritionally important metals as well as the toxic heavy metal cadmium.

  9. ZIP14 downregulation is likely involved in the depletion of zinc in the hepatoma cells in Hepatocellular cancer

  10. The transporter ZIP14 is up-regulated along the entire gastrointestinal tract by proinflammatory conditions.

Mouse (Murine) Solute Carrier Family 39 (Zinc Transporter), Member 14 (SLC39A14) interaction partners

  1. Results suggest that aberrant zinc distribution observed with Zip14 ablation impacts adipose cytokine production and metabolism, ultimately increasing fat deposition when exposed to endotoxin.

  2. Slc39a14 deficiency in hemochromatotic mice greatly diminished iron loading of the liver and prevented iron deposition in hepatocytes and pancreatic acinar cells.

  3. PrP(C (show PRNP ELISA Kits)) promotes, and possibly regulates, the uptake of iron through DMT1 (show SLC11A2 ELISA Kits) and Zip14 via its ferrireductase activity.

  4. Zinc transporter ZIP14 influences aspects of the pathophysiology of nonlethal polymicrobial murine sepsis induced by cecal ligation/puncture through zinc delivery.

  5. Oral cadmium chloride administration to ZIP14 knockout mice results in time dependent changes in gene expression.

  6. ZIP14 is a basolaterally localized protein in enterocytes and is involved in endosomal trafficking of zinc and is necessary for proper maintenance of intestinal tight junctions

  7. Hepatic ZIP14 protein levels are upregulated in iron-loaded hypotransferrinemic mice.

  8. We ligated mouse ZIP14A, ZIP14B and ZIP8 cDNA coding regions into the Xenopus-specific vector pXFRM, transcribed these in vitro, and microinjected the capped RNAs into Xenopus oocytes. K(m) and V(max) values for Cd, Zn and Fe uptake were determined.

  9. Zip14 expression induced by lipopolysaccharides in macrophages attenuates inflammatory response

  10. The knockdown of ZIP8 (show SLC39A8 ELISA Kits), ZIP14 or DMT1 (show SLC11A2 ELISA Kits) by siRNA transfection significantly reduced the uptake of Cd(2 (show CD2 ELISA Kits)+) and Mn(2+) from the apical membrane.

SLC39A14 Antigen Profile

Antigen Summary

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003

Gene names and symbols associated with SLC39A14

  • solute carrier family 39 (zinc transporter), member 14 (SLC39A14) antibody
  • solute carrier family 39 (zinc transporter), member 14 (Slc39a14) antibody
  • BC021530 antibody
  • cig19 antibody
  • fad123 antibody
  • G630015O18Rik antibody
  • LZT-Hs4 antibody
  • NET34 antibody
  • Zip14 antibody

Protein level used designations for SLC39A14

LIV-1 subfamily of ZIP zinc transporter 4 , ZIP-14 , Zrt-, Irt-like protein 14 , solute carrier family 39 (metal ion transporter), member 14 , solute carrier family 39 member 14 , zinc transporter ZIP14 , zrt- and Irt-like protein 14 , FAD-123 , Zrt- and Irt-like protein 14 , factor for adipocyte differentiation 123 , Zinc transporter ZIP14

GENE ID SPECIES
23516 Homo sapiens
213053 Mus musculus
306009 Rattus norvegicus
515437 Bos taurus
100172692 Pongo abelii
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