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anti-Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4) Antibodies

SLC39A4 encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. Additionally we are shipping Solute Carrier Family 39 (Zinc Transporter), Member 4 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC39A4 55630 Q6P5W5
SLC39A4 72027 Q78IQ7
SLC39A4 300051 A0JPN2
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Top anti-Solute Carrier Family 39 (Zinc Transporter), Member 4 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$201.19
Details

SLC39A4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)
,

Rat (Rattus)


Top referenced anti-Solute Carrier Family 39 (Zinc Transporter), Member 4 Antibodies

  1. Human Polyclonal SLC39A4 Primary Antibody for WB - ABIN2781654 : Li, Zhang, Liu, Bharadwaj, Wang, Wang, Zhang, Liuzzi, Chang, Cousins, Fisher, Brunicardi, Logsdon, Chen, Yao: Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

  2. Human Polyclonal SLC39A4 Primary Antibody for ELISA, WB - ABIN1451823 : Nusbaum, Mikkelsen, Zody, Asakawa, Taudien, Garber, Kodira, Schueler, Shimizu, Whittaker, Chang, Cuomo, Dewar, FitzGerald, Yang, Allen, Anderson, Asakawa, Blechschmidt, Bloom, Borowsky, Butler, Cook et al.: DNA sequence and analysis of human chromosome 8. ... in Nature 2006 (PubMed)

More Antibodies against Solute Carrier Family 39 (Zinc Transporter), Member 4 Interaction Partners

Human Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4) interaction partners

  1. Data sho (show SPRN Antibodies) that silencing of zinc transporter ZIP4 resulted in increased bone tissue mineral density, and restoration of bone strength.

  2. The results described a previously uncharacterized role of ZIP4 in apoptosis resistance and elucidated a novel pathway through which ZIP4 regulates pancreatic cancer growth.

  3. In glioma tumors, high ZIP4 expression was significantly associated with higher grade.

  4. Developed is a structural model of ZIP4 by combining protein prediction methods with in situ experiments. Insight into the permeation pathway of ZIP4 is provided.

  5. SLC39A4 mutations have roles in zinc deficiency

  6. Both acrodermatitis mutations cause absence of the ZIP4 transporter cell surface expression and nearly absent zinc uptake.

  7. ZIP4 activates the zinc-dependent transcription factor CREB (show CREB1 Antibodies) and requires this transcription factor to increase miR (show MLXIP Antibodies)-373 expression through the regulation of its promoter.

  8. High ZIP4 expression is associated with glioma.

  9. resulkts indicate ZIP4 is the only zinc transporter that is significantly up-regulated in pancreatic cancer and might be the major zinc transporter that plays an important role in pancreatic cancer growth

  10. The results suggest that ZIP4 may be a tumor suppressor gene and down-regulation of ZIP4 may be a critical early event in the development of prostate carcinoma

Mouse (Murine) Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4) interaction partners

  1. While Zip4 was not found to be essential for proper glucose homeostasis and insulin (show INS Antibodies) secretion in vivo in mice, this study found that Zip4 mediates increases in cytoplasmic and granular zinc pools and stimulates glucose dependent insulin (show INS Antibodies) secretion in-vitro

  2. These studies strongly suggest that wasting and lethality in acrodermatitis enteropathica patients reflects the loss-of-function of the intestine zinc transporter ZIP4, which leads to abnormal Paneth cell gene expression

  3. Cell migration assays revealed that RNAi knockdown of Zip4 in Hepa cells depressed in vitro migration whereas forced over-expression in Hepa cells and MCF-7 cells enhanced in vitro migration

  4. ZIP4 physically interacts with tPA (show PLAT Antibodies), correlating with an increased intracellular zinc influx and lysosomal sequestration after excitotoxin stimulation. Changes in prosurvival signals support the idea that this sequestration results in neuroprotection.

  5. results provide compelling evidence that ZIP4 is a zinc transporter that plays an important role in zinc homeostasis, a process that is defective in acrodermatitis enteropathica in humans

  6. ZIP4 and ZIP5 (show SLC39A5 Antibodies) have roles in the adaptive response to dietary zinc in mice

  7. that heterozygous mutations in the acrodermatitis gene Zip4 (Slc39a4) may be associated with a wider range of developmental defects than was previously appreciated, particularly when dietary zinc is limiting.

  8. ZIP4 is induced by zinc deficiency in cultured mouse Hepa cells and is rapidly degraded in response to added zinc

  9. The processing of ZIP4 may represent a significant regulatory mechanism controlling its function.

  10. KLF4 (show KLF4 Antibodies) is induced during zinc restriction and is a transcription factor involved in adaptive regulation of the zinc transporter ZIP4

Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4) Antigen Profile

Protein Summary

This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC39A4

  • solute carrier family 39 (zinc transporter), member 4 (SLC39A4) antibody
  • solute carrier family 39 (zinc transporter), member 4 (slc39a4) antibody
  • solute carrier family 39 (zinc transporter), member 4 (Slc39a4) antibody
  • 1600025H15Rik antibody
  • AEZ antibody
  • AU041686 antibody
  • AWMS2 antibody
  • ZIP4 antibody

Protein level used designations for SLC39A4

solute carrier family 39 (zinc transporter), member 4 , ZIP4 , zinc transporter ZIP4-like , zinc transporter ZIP4 , zrt- and Irt-like protein 4 , ZIP-4 , solute carrier family 39 member 4 , solute carrier family 39, member 4 , activated in W/Wv mouse stomach 2 , mAWMS2

GENE ID SPECIES
464462 Pan troglodytes
482096 Canis lupus familiaris
562762 Danio rerio
100400831 Callithrix jacchus
100597084 Nomascus leucogenys
55630 Homo sapiens
510951 Bos taurus
72027 Mus musculus
300051 Rattus norvegicus
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