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anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) Antibodies

The protein encoded by SLC4A1 is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. Additionally we are shipping Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Proteins (9) and Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC4A1 6521 P02730
SLC4A1 20533 P04919
SLC4A1 24779 P23562
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Top anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p), WB Anti- Band 3 Picoband antibody,IHC(P) IHC(P): Rat Kidney Tissue Anti- Band 3 Picoband antibody, Western blotting All lanes: Anti Band 3  at 0.5ug/ml Lane 1: Rat Brain Tissue Lysate at 50ug Lane 2: Rat Kidney Tissue Lysate at 50ug Lane 3: Rat Liver Tissue Lysate at 50ug Lane 4: Rat Spleen Tissue Lysate at 50ug Lane 5: Human Placenta Tissue Lysate at 50ug Predicted bind size: 102KD Observed bind size: 102KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Placenta, Erythrocytes (formalin-fixed, paraffin-embedded) stained with SLC4A1 antibody ABIN290275 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of SLC4A1 expression in transfected 293T cell line by SLC4A1 MaxPab polyclonal antibody.Lane 1: SLC4A1 transfected lysate(100.21 KDa).Lane 2: Non-transfected lysate. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p), WB Spleen 50 μg Log in to see 8 to 10 Days
$676.50
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$365.20
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details

SLC4A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Antibodies

  1. Human Polyclonal SLC4A1 Primary Antibody for WB - ABIN2778128 : Kittanakom, Cordat, Akkarapatumwong, Yenchitsomanus, Reithmeier: Trafficking defects of a novel autosomal recessive distal renal tubular acidosis mutant (S773P) of the human kidney anion exchanger (kAE1). in The Journal of biological chemistry 2004 (PubMed)

  2. Human Polyclonal SLC4A1 Primary Antibody for WB - ABIN520240 : Govekar, Kawle, Thomas, Advani, Pv, Zingde: Eryptotic phenotype in chronic myeloid leukemia: contribution of neutrophilic cathepsin g. in Anemia 2012 (PubMed)

More Antibodies against Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) Interaction Partners

Human Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) interaction partners

  1. The evolutionary origin of Southeast Asian Ovalocytosis, characterizing DNA sequence variation around the causal mutation in the SLC4A1 gene.

  2. This study is considered as a pilot study showing the importance of AE1 mutations in Iranian children with DRTA.

  3. The authors demonstrate that the initial vacuolar membrane around internalized Babesia divergens is formed from protein and lipid components of the red blood cells plasma membrane, including band 3, glycophorin A and spectrin.

  4. this study reports the crystal structure of the band 3 anion exchanger domain (AE1(CTD)) at 3.5 angstroms.

  5. Deficiency in Band 3 is associated with Hereditary Spherocytosis.

  6. Results indicate that Tryptophan residues play differential roles in AE1 expression and function depending on their location in the protein and that Trp (show TBPL1 Antibodies) mutants with low expression are misfolded and retained in the endoplasmic reticulum.

  7. Kidney AE1 actually associates with epithelial ankyrin-G (show ANK3 Antibodies) and renal ammonium transporter RhBG, which also binds ankyrin-G (show ANK3 Antibodies).

  8. Activities of AE1 and the sodium pump are coregulated in kidney.

  9. The study reports the refinement for a protein heterodimer complex using limited EPR (show EREG Antibodies) spectroscopic data and a rigid-body docking algorithm: a three-dimensional model for an ankyrin 1 (show ANK1 Antibodies)-BND3 complex.

  10. Partial pyruvate kinase deficiency aggravates the phenotypic expression of band 3 deficiency in a family with hereditary spherocytosis.

Mouse (Murine) Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) interaction partners

  1. NH4Cl loading elicited adaptive doubling of AE1 mRNA in GPR4 (show GPR4 Antibodies)+/+, but a 50% less pronounced response in GPR4 (show GPR4 Antibodies)-/-.

  2. Activities of AE1 and the sodium pump are coregulated in kidney.

  3. AE1 is enhanced by acidosis, NaCl, and the combination of DOCA and NaHCO3 in renal collecting ducts.

  4. These findings indicate that the conserved YXXPhi sequence or a noncanonical YXXXPhi sequence in the N-terminal region facilitates the endocytic recycling of erythroid AE1 through a clathrin-mediated pathway.

  5. These results suggest that AE1 is potentially a key therapeutic target and the silencing of AE1 expression in gastric mucosa could provide a new therapeutic approach for treating gastric cancer.

  6. These results demonstrate that mammalian erythroblast enucleation does not depend on the membrane integrity generated by the ankyrin-band 3 complex.

  7. Data suggest that glycophorin A (Gpa (show GYPA Antibodies)) increases expression and activity of Cl-/HCO3- exchanger Ae1, that G719D mutation renders Ae1 mutant constructs GPA (show GYPA Antibodies)-unresponsive, and suggests a role for Ae1 amino acids 22-28 in GPA (show GYPA Antibodies) responsiveness.

  8. podocyte protein kidney anion exchanger 1 interacts with nephrin (show NPHS1 Antibodies) and kinase to maintain the structure and function of the glomerular basement membrane.

  9. This review explores what is known about the erythrocyte membrane protein band 3 complexes of mice and humans, focussing on the observed species differences and their potential functional consequences.

  10. Analysis of 3 new alleles reveals previously unknown consequences of red blood cell (RBC (show CACNA1C Antibodies)) spectrin deficiency, resulting in markedly reduced RBC (show CACNA1C Antibodies) membrane spectrin content, decreased band 3, and absent beta-adducin (show ADD2 Antibodies).

Solute Carrier Family 4, Anion Exchanger, Member 1 (erythrocyte Membrane Protein Band 3, Diego Blood Group) (SLC4A1) Antigen Profile

Protein Summary

The protein encoded by this gene is part of the anion exchanger (AE) family and is expressed in the erythrocyte plasma membrane, where it functions as a chloride/bicarbonate exchanger involved in carbon dioxide transport from tissues to lungs. The protein comprises two domains that are structurally and functionally distinct. The N-terminal 40kDa domain is located in the cytoplasm and acts as an attachment site for the red cell skeleton by binding ankyrin. The glycosylated C-terminal membrane-associated domain contains 12-14 membrane spanning segments and carries out the stilbene disulphonate-sensitive exchange transport of anions. The cytoplasmic tail at the extreme C-terminus of the membrane domain binds carbonic anhydrase II. The encoded protein associates with the red cell membrane protein glycophorin A and this association promotes the correct folding and translocation of the exchanger. This protein is predominantly dimeric but forms tetramers in the presence of ankyrin. Many mutations in this gene are known in man, and these mutations can lead to two types of disease: destabilization of red cell membrane leading to hereditary spherocytosis, and defective kidney acid secretion leading to distal renal tubular acidosis. Other mutations that do not give rise to disease result in novel blood group antigens, which form the Diego blood group system. Southeast Asian ovalocytosis (SAO, Melanesian ovalocytosis) results from the heterozygous presence of a deletion in the encoded protein and is common in areas where Plasmodium falciparum malaria is endemic. One null mutation in this gene is known, resulting in very severe anemia and nephrocalcinosis.

Gene names and symbols associated with SLC4A1

  • solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (SLC4A1) antibody
  • solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) (slc4a1) antibody
  • Band 3 (LOC100136769) antibody
  • solute carrier family 4 (anion exchanger), member 1 (SLC4A1) antibody
  • solute carrier family 4 (anion exchanger), member 1 (Slc4a1) antibody
  • solute carrier family 4, anion exchanger, member 1 (SLC4A1) antibody
  • Ae1 antibody
  • BND3 antibody
  • CD233 antibody
  • DI antibody
  • EAT antibody
  • Empb3 antibody
  • EPB3 antibody
  • FR antibody
  • l11Jus51 antibody
  • LOC100136769 antibody
  • MGC80391 antibody
  • RTA1A antibody
  • slc4a1 antibody
  • SW antibody
  • WD antibody
  • WD1 antibody
  • WR antibody

Protein level used designations for SLC4A1

solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) , erythroid anion exchanger 1 , band 3 anion transport protein , solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3) , Band 3 , band 3 anion transport protein-like , Diego blood group , Froese blood group , Swann blood group , Waldner blood group , Wright blood group , anion exchange protein 1 , anion exchanger 1 , anion exchanger-1 , erythrocyte membrane protein band 3 , erythroid anion exchange protein , solute carrier family 4, anion exchanger, number 1 , AE 1 , MEB3 , solute carrier family 4 member 1 , Solute carrier family 4, member 1, anion exchange protein 1 (kidney band 3) , erythrocyte anion transport protein

GENE ID SPECIES
395371 Gallus gallus
443978 Xenopus laevis
454727 Pan troglodytes
100009691 Equus caballus
100136769 Oncorhynchus mykiss
100174401 Pongo abelii
100349024 Oryctolagus cuniculus
100483431 Ailuropoda melanoleuca
100486998 Xenopus (Silurana) tropicalis
100514249 Sus scrofa
490939 Canis lupus familiaris
100563543 Anolis carolinensis
100579389 Nomascus leucogenys
6521 Homo sapiens
20533 Mus musculus
24779 Rattus norvegicus
396532 Gallus gallus
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