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Solute Carrier Family 4, Anion Exchanger, Member 2 (erythrocyte Membrane Protein Band 3-Like 1) Proteins (SLC4A2)

Plasma membrane anion exchange protein of wide distribution.. Additionally we are shipping SLC4A2 Antibodies (15) and SLC4A2 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC4A2 6522 P04920
SLC4A2 20535 P13808
Rat SLC4A2 SLC4A2 24780 P23347
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Top SLC4A2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SLC4A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Solute Carrier Family 4, Anion Exchanger, Member 2 (erythrocyte Membrane Protein Band 3-Like 1) (SLC4A2) Interaction Partners

Cow (Bovine) Solute Carrier Family 4, Anion Exchanger, Member 2 (erythrocyte Membrane Protein Band 3-Like 1) (SLC4A2) interaction partners

  1. These results indicate that a deletion mutation within bovine SLC4A2 is associated with osteopetrosis (show CSF1 Proteins) in Red Angus cattle.

Human Solute Carrier Family 4, Anion Exchanger, Member 2 (erythrocyte Membrane Protein Band 3-Like 1) (SLC4A2) interaction partners

  1. AE2 is a major pathway for basolateral Cl(-) loading during cAMP-stimulated secretion of Cl(-) and fluid by Calu (show CALU Proteins)-3 cells

  2. A novel signal pathway involved in gastrin (show GAST Proteins)-stimulated AE2 expression mediated by EGR1 (show EGR1 Proteins) in gastric cancer cells.

  3. miR (show MLXIP Proteins)-506 is up-regulated in primary biliary cirrhosis, binds the 3'UTR region of AE2 mRNA, and prevents protein translation, leading to diminished AE2 activity and impaired biliary secretory functions.

  4. CTLA4 (show CTLA4 Proteins) and SLC4A2 genetic polymorphisms are differentially associated with primary biliary cirrhosis development and progression, as well as anti-gp210 (show NUP210 Proteins) or anti-centromere antibody production, in Japanese PBC (show DLAT Proteins) patients

  5. Dysfunctions related to AE2 might have a role in the pathogenesis of primary biliary cirrhosis.

  6. AE2 mediated-apoptosis of endothelial cells induced by high glucose was Caspase-3 (show CASP3 Proteins)-dependent.

  7. AE2 operates in parallel with NHE1 (show SLC9A1 Proteins) to regulate pH(i) during RVD of human cervical cancer cells.

  8. Oxidative stress activates anion exchange protein 2 and AP-1 (show FOSB Proteins) in airway epithelial cells.

  9. findings suggest that HNF1 (show HNF1A Proteins) may have a major role in upregulating alternative transcription of the AE2 gene in the liver, and therefore it may contribute to the biliary secretion of bicarbonate in response to certain stimuli

  10. The results indicated that overexpression of AE2 may be involved in the development of human HCC (show FAM126A Proteins).

Mouse (Murine) Solute Carrier Family 4, Anion Exchanger, Member 2 (erythrocyte Membrane Protein Band 3-Like 1) (SLC4A2) interaction partners

  1. AE2 deficiency results in intrahepatic T-cell activation and PD-1 (show PDCD1 Proteins)/PD-L1 (show CD274 Proteins) mediated deletion, favoring autoimmune cholangitis.

  2. GnRH (show GNRH1 Proteins) neurons were immunopositive for NKCC1 (show SLC12A2 Proteins) and AE2.

  3. These findings demonstrate that CD8 (show CD8A Proteins)(+) T cells are critically dependent on Ae2 for pHi homeostasis and tuning of cell proliferation and activation. Ae2 thus constitutes a novel target to modulate CD8 (show CD8A Proteins)(+) T-cell responses.

  4. Rescue of SLC4A2-deficient osteoclasts with functionally defined mutants of SLC4A2 indicates regulation of actin cytoskeletal reorganization by anion-exchange activity and intracellular pH, independent of SLC4A2's long N-terminal cytoplasmic domain.

  5. expression of Slc4a2 significantly decreased in enamel organs from Mmp20 (show MMP20 Proteins)(-/-) mice. A feedback mechanism regulates ion-responsive gene expression during enamel development.

  6. AE2 is a component of the basolateral ion transport mechanisms that support anion secretion in the proximal colon.

  7. GFP-tagged Ae2 localization depends upon MAPK (show MAPK1 Proteins) activity

  8. results are consistent with the hypothesis that AE2 mediates the major portion of the exchange across the basolateral membrane of mouse parotid and sublingual acinar cells

  9. Male Ae2-/- mice are infertile, with an interruption of spermiogenesis.

  10. AE2 is essential for gastric acid secretion and for normal development of secretory canalicular and tubulovesicular membranes in mouse parietal cells

SLC4A2 Protein Profile

Protein Summary

Plasma membrane anion exchange protein of wide distribution.

Gene names and symbols associated with SLC4A2

  • solute carrier family 4 (anion exchanger), member 2 (Slc4a2)
  • solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (SLC4A2)
  • solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) (LOC100224615)
  • solute carrier family 4 (anion exchanger), member 2 (SLC4A2)
  • Ae2 protein
  • Aep2 protein
  • B3RP protein
  • BND3L protein
  • EPB3L1 protein
  • HKB3 protein
  • NBND3 protein
  • SLC4A2 protein

Protein level used designations for SLC4A2

AE 2 , AE2 anion exchanger , anion exchange protein 2 , anion exchanger 2 a , non-erythroid band 3-like protein , solute carrier family 4 member 2 , AE2-1 anion exchanger , chloride-bicarbonate anion exchanger AE2 , SLC4A2 anion exchanger , chloride-bicarbonate exchanger , solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1) , anion exchanger 2 , anion exchanger 2 type a , anion exchanger 2 type b1 , anion exchanger 2 type b2 , erythrocyte membrane protein band 3-like 1 , band 3-related protein , B3RP-2 , Solute carrier family 4, member 2, anion exchange protein 2 , band 3-related protein 2

GENE ID SPECIES
100135618 Cavia porcellus
395809 Gallus gallus
397203 Sus scrofa
404084 Bos taurus
463890 Pan troglodytes
475538 Canis lupus familiaris
713966 Macaca mulatta
100172030 Pongo abelii
100224615 Taeniopygia guttata
100599599 Nomascus leucogenys
6522 Homo sapiens
20535 Mus musculus
24780 Rattus norvegicus
100009159 Oryctolagus cuniculus
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