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Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4) ELISA Kits

SLC4A4 encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Additionally we are shipping SLC4A4 Antibodies (46) and SLC4A4 Proteins (14) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC4A4 SLC4A4 54403 O88343
Anti-Human SLC4A4 SLC4A4 8671 Q9Y6R1
Anti-Rat SLC4A4 SLC4A4 84484 Q9JI66
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More ELISA Kits for SLC4A4 Interaction Partners

Mouse (Murine) Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4) interaction partners

  1. NBCe1 is necessary for normal proximal tubule NaDC-1 (show SLC13A2 ELISA Kits) expression and 2-oxoglutarate metabolism, and deletion results in stimulation of a novel citrate reabsorptive pathway

  2. Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes

  3. Study presented evidence for mouse cortical astrocytes and Xenopus oocytes that total "effective" cytosolic H+ buffering does not only include instantaneous, physicochemical buffering, but also rapid bicarbonate transport via NBCe1

  4. NBCe1 deletion caused a gene dose-related decrease in ammonia excretion

  5. Results demonstrate that transcriptional regulation and targeting of NBCe1, as well as functional operation of NBCe1, may occur through multiple signaling pathways

  6. The expression of NBCe1 in ameloblasts and the papillary layer cell depends on the developmental stage and possibly responds to pH changes.

  7. NBCe1 function is regulated by protein kinase C (show PKC ELISA Kits) in murine colonic crypts.

  8. Our results demonstrate a surprisingly high apparent bicarbonate sensitivity mediated by NBCe1 in cortical astrocytes

  9. acidosis-induced NBCe1-A, but not NBCe1-B/C, trafficking is mediated by Rab8a (show RAB8A ELISA Kits).

  10. Cloning of NBCe1-D and NBCe1-E, both lacking a 27-nucleotide cassette I, reveals a novel alternative splicing unit in the mouse Slc4a4 gene.

Human Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4) interaction partners

  1. miR (show MLXIP ELISA Kits)-224 was significantly downregulated as ameloblasts differentiated, in parallel with upregulation of SLC4A4 and CFTR (show CFTR ELISA Kits).

  2. The R298S is a temperature-sensitive mutation in NBCe1-A that results in instability of the colloidal system leading to abnormal aggregation.

  3. our results indicate that SLC4A4 contributes to the HCO3(-) transport and tumor cell phenotype

  4. These results revealed that insulin (show INS ELISA Kits) can stimulate PT sodium transport even in type 2 diabetes with overt nephropathy.

  5. Data indicate that a domain-like structure formed by extracellular loop 3 (EL-3 (show SPTB ELISA Kits)) is present at the SLC4 Na+-coupled transporter NBCe1-A dimeric interface.

  6. The cell membrane gene SLC4A4 and the trafficking regulator gene COPA (show COPA ELISA Kits), which also plays an important role in early endosome maturation, were identified for the cellular entry of poly-arginine peptide.

  7. Our results demonstrate a surprisingly high apparent bicarbonate sensitivity mediated by NBCe1 in cortical astrocytes

  8. a clear understanding of the structure-functional properties of NBCe1 is a prerequisite for elucidating the mechanisms of defective transepithelial bicarbonate transport--{REVIEW}

  9. A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters.

  10. Suggest NBce1-A missense mutation as new pathogenic mechanism for generating human proximal tubular acidosis.

Cow (Bovine) Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4) interaction partners

  1. AHCYL2 (show AHCYL2 ELISA Kits) is a potential regulator of NBCe1-B in mammalian cells.

  2. these results suggest that IRBIT (show AHCYL1 ELISA Kits) may reduce the apparent affinity for Mg(2 (show MCOLN1 ELISA Kits)+)(i) in inhibition of NBCe1-B activity in mammalian cells.

  3. Data indicate that NBC1 (1Na(+)-3HCO(3)(-) cotransporter) plays a key role in transendothelial bicarbonate ion flux and is functional only at the basolateral membrane.

  4. These results suggest that Mg2 (show MCOLN1 ELISA Kits)+ may be a cytosolic factor that limits intrinsic cotransport activity of NBCe1-B in mammalian cells.

Rabbit Solute Carrier Family 4, Sodium Bicarbonate Cotransporter, Member 4 (SLC4A4) interaction partners

  1. features of NBCe1-like activity in renal preparations are influenced by yet-to-be-identified renal factors

SLC4A4 Antigen Profile

Antigen Summary

This gene encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Mutations in this gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC4A4

  • solute carrier family 4 (anion exchanger), member 4 (Slc4a4) antibody
  • solute carrier family 4 (sodium bicarbonate cotransporter), member 4 (SLC4A4) antibody
  • solute carrier family 4, sodium bicarbonate cotransporter, member 4 (Slc4a4) antibody
  • solute carrier family 4, sodium bicarbonate cotransporter, member 4 (SLC4A4) antibody
  • AI835705 antibody
  • HHNMC antibody
  • HNBC1 antibody
  • KNBC antibody
  • NBC antibody
  • Nbc1 antibody
  • NBC2 antibody
  • Nbc4 antibody
  • NBCE1 antibody
  • NBCe1-A antibody
  • PNBC antibody
  • SLC4A5 antibody

Protein level used designations for SLC4A4

Na(+)/HCO3(-) cotransporter , electrogenic sodium bicarbonate cotransporter 1 , electrogenic sodium bicarbonate cotransporter NBCe1 variant D , pancreas sodium bicarbonate cotransporter , sodium bicarbonate cotransporter , solute carrier family 4 member 4 , solute carrier family 4, sodium bicarbonate cotransporter, member 4 , kNBC1 , sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas) , solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type , solute carrier family 4, sodium bicarbonate cotransporter, member 5 , NBC-like protein , Na+HCO3- cotransporter 4 , solute carrier family 4 (anion exchanger), member 4 , solute carrier family 4, member 4 , sodium bicarbonate cotransporter member 4 , solute carrier family 4, sodium bicarbonate cotransporter member 4 , duodenal sodium bicarbonate cotransport protein NBC1 , Na+-HCO3- exchanger

GENE ID SPECIES
54403 Mus musculus
8671 Homo sapiens
84484 Rattus norvegicus
282360 Bos taurus
503546 Sus scrofa
100008727 Oryctolagus cuniculus
475171 Canis lupus familiaris
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