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Solute Carrier Family 4, Sodium Bicarbonate Transporter, Member 10 (SLC4A10) ELISA Kits

SLC4A10 belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. Additionally we are shipping SLC4A10 Proteins (4) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC4A10 SLC4A10 94229 Q5DTL9
Anti-Human SLC4A10 SLC4A10 57282 Q6U841
Anti-Rat SLC4A10 SLC4A10 295645 Q80ZA5
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More ELISA Kits for SLC4A10 Interaction Partners

Mouse (Murine) Solute Carrier Family 4, Sodium Bicarbonate Transporter, Member 10 (SLC4A10) interaction partners

  1. finding show that somatodendritic expression of Slc4a10 undergoes neuron type- and input pathway-dependent regulation in adult brains

  2. We conclude that alternative transcription and splicing of Slc4a10 products are regulated in a tissue-specific manner. Our findings provide critical insights that will greatly influence the study of the physiology of NBCn2.

  3. Data indicate that sodium-driven chloride bicarbonate exchanger NCBE (Slc4a10) is strongly expressed in the mouse retina.

  4. Slc4a10 knockout is more deleterious to choroid plexus epithelium than aquaporin 1 (AQP1 (show AQP1 ELISA Kits)) knockout.

  5. Cloning of the NBCn2-A transcript demonstrates that it is dominant in the subcortex and medulla of mouse brain.

  6. NBCn2 is highly expressed in choroid plexus, cortex, molecular layer of cerebellum, hippocampus, and some specific regions of the brainstem.

  7. slc4a10 expressed in mammalian cells encodes a Na(+)-dependent Cl(-)/HCO(3)(-) exchanger in which four specific charged amino acids seem necessary for ion transport.

  8. SLC4A10 gene product and NBCn1 (show SLC4A7 ELISA Kits) both function as basolateral HCO3- entry pathways and that the SLC4A10 gene product may be responsible for the stilbene-sensitive Na+-HCO3- uptake that is essential for cerebrospinal fluid production.

  9. NCBE is expressed in the peripheral nervous system and in non-neuronal tissues as the choroid plexus, the dura, and some epithelia including the acid secreting epithelium of the stomach and the duodenal epithelium.

  10. most cases, hypoxia reduced NBCn1 (show SLC4A7 ELISA Kits) levels by 20-50%, and NCBE levels by 15-40% in cerebral cortex, subcortex, cerebellum, and hippocampus, both after 14 and 28 days, and in both pups and adults.

Human Solute Carrier Family 4, Sodium Bicarbonate Transporter, Member 10 (SLC4A10) interaction partners

  1. There was no association between common sequence variants in the AQP1 (show AQP1 ELISA Kits) or SLC4A10 genes and primary open-angle glaucoma in the Caucasian population.

  2. propose to rename NCBE as the second electroneutral Na/HCO(3) cotransporter, NBCn2

  3. SLC4A10 (OMIM 605556), a sodium bicarbonate transporter (show SLC4A7 ELISA Kits) gene with high expression in the cerebral cortex and hippocampus, was disrupted by the translocation breakpoint on chromosome 2q24.

SLC4A10 Antigen Profile

Antigen Summary

This gene belongs to a small family of sodium-coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by this gene was initially identified as a sodium-driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium/bicarbonate cotransport activity is independent of any chloride ion countertransport under physiological conditions. This gene is now classified as a member A10 of the SLC4 family of transmembrane solute carriers. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with SLC4A10

  • solute carrier family 4, sodium bicarbonate transporter-like, member 10 (SLC4A10) antibody
  • solute carrier family 4, sodium bicarbonate transporter, member 10 (SLC4A10) antibody
  • solute carrier family 4, sodium bicarbonate transporter, member 10 (slc4a10) antibody
  • solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 (Slc4a10) antibody
  • solute carrier family 4, sodium bicarbonate transporter, member 10 (Slc4a10) antibody
  • mKIAA4136 antibody
  • NBCn2 antibody
  • NCBE antibody

Protein level used designations for SLC4A10

solute carrier family 4, sodium bicarbonate transporter-like, member 10 , solute carrier family 4, sodium bicarbonate transporter, member 10 , solute carrier family 4, sodium bicarbonate transporter-like, member 10-like , sodium-driven chloride bicarbonate exchanger-like , sodium bicarbonate cotransporter NBCn2-E , sodium bicarbonate cotransporter member 10 variant NBCn2-E' , sodium-driven chloride bicarbonate exchanger , solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 , solute carrier family 4 member 10

GENE ID SPECIES
424188 Gallus gallus
459688 Pan troglodytes
478766 Canis lupus familiaris
705263 Macaca mulatta
100022324 Monodelphis domestica
100061059 Equus caballus
100082133 Ornithorhynchus anatinus
100332216 Danio rerio
100341167 Oryctolagus cuniculus
100381059 Xenopus laevis
100393662 Callithrix jacchus
100466676 Ailuropoda melanoleuca
100512016 Sus scrofa
100604223 Nomascus leucogenys
94229 Mus musculus
57282 Homo sapiens
295645 Rattus norvegicus
517077 Bos taurus
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