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Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11) ELISA Kits

SLC4A11 encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Additionally we are shipping SLC4A11 Antibodies (17) and SLC4A11 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat SLC4A11 SLC4A11 311423  
Anti-Mouse SLC4A11 SLC4A11 269356 A2AJN7
Anti-Human SLC4A11 SLC4A11 83959 Q8NBS3
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More ELISA Kits for SLC4A11 Interaction Partners

Xenopus laevis Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11) interaction partners

Mouse (Murine) Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11) interaction partners

  1. Successful knockout of the Slc4a11 gene was confirmed by immunohistochemistry and RT-PCR. Slit-lamp photography and AS-OCT (show Plxna2 ELISA Kits) showed progressive corneal edema.

  2. Loss of SLC4A11 leads to morphological changes in the fibrocytes and deafness.

  3. Results demonstrate the importance of NaBC1 (show BCAS1 ELISA Kits) in the audio-vestibular system and provide support for the hypothesis that SLC4A11 should be considered a potential candidate gene in patients with isolated sensorineural vestibular hearing abnormalities.

Human Solute Carrier Family 4, Sodium Borate Transporter, Member 11 (SLC4A11) interaction partners

  1. we report posterior polymorphous corneal dystrophy resulting from a de novo mutation in ZEB1 (show ZEB1 ELISA Kits). Additionally, we present a congenital hereditary endothelial dystrophy case with a thin Descemet membrane with a novel compound heterozygous SLC4A11 mutation.

  2. we review the current knowledge on the role of the SLC4A11 gene, protein, and its mutations in the pathophysiology and clinical presentation of CHED (show CDK13 ELISA Kits). [review]

  3. We report a novel nonsense mutation of the SLC4A11 gene in the patient with CHED2. In addition, one of heterozygous carriers in this family showed features of late onset Fuchs endothelial corneal dystrophy.

  4. SLC4A11 mutations contribute to 11% (5/45) of sporadic late-onset Late-onset Fuchs endothelial corneal dystrophy (FECD (show COL8a2 ELISA Kits)) in the cohort studied.

  5. SLC4A11 is a novel NH3/H+ co-transporter.

  6. We found that cells containing mutant SLC4A11 are more vulnerable to oxidative and mitochondrial damage, less able to overcome oxidative stress through the expression of sufficient levels of antioxidant genes, and are more prone to apoptotic death.

  7. In contrast to the Slc4a11(-/-) mouse, no abnormalities in daily renal ion excretion or polyuria were observed in the Harboyan syndrome patient.

  8. Potential therapeutic agents to improve the functional impairment of specific SLC4A11 mutant transporters.

  9. Our observations suggest that congenital hereditary endothelial dystrophy caused by homozygous SLC4A11 mutations progresses to Harboyan syndrome, but the severity of this may vary considerably.

  10. Variation in the COL8A2 (show COL8a2 ELISA Kits), SLC4A11, and ZEB1 (show ZEB1 ELISA Kits) genes is present in only a small fraction of African American cases and as such does not appear to significantly contribute to the genetic risk of Fuchs endothelial corneal dystrophy.

SLC4A11 Antigen Profile

Antigen Summary

This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.

Gene names and symbols associated with SLC4A11

  • solute carrier family 4, sodium borate transporter, member 11 (Slc4a11) antibody
  • solute carrier family 4, sodium borate transporter, member 11 (SLC4A11) antibody
  • solute carrier family 4, sodium borate transporter, member 11 (slc4a11) antibody
  • solute carrier family 4, sodium bicarbonate transporter-like, member 11 (Slc4a11) antibody
  • AI503023 antibody
  • BTR1 antibody
  • CDPD1 antibody
  • CHED2 antibody
  • dJ794I6.2 antibody
  • NABC1 antibody
  • si:dkey-12j14.4 antibody

Protein level used designations for SLC4A11

sodium bicarbonate transporter-like protein 11 , solute carrier family 4, sodium bicarbonate transporter-like, member 11 , solute carrier family 4, sodium borate transporter, member 11 , sodium-coupled borate transporter , sodium bicarbonate transporter-like protein 11-like , solute carrier family 4 member 11 , Sodium borate cotransporter 1 , Solute carrier family 4 member 11 , bicarbonate transporter-related protein 1 , bicarbonate transporter related protein 1 , sodium-coupled borate cotransporter 1

GENE ID SPECIES
311423 Rattus norvegicus
422943 Gallus gallus
485796 Canis lupus familiaris
532407 Bos taurus
718393 Macaca mulatta
100066656 Equus caballus
100157069 Sus scrofa
100219606 Taeniopygia guttata
100381166 Xenopus laevis
100406932 Callithrix jacchus
100444814 Pongo abelii
100486382 Xenopus (Silurana) tropicalis
458058 Pan troglodytes
559346 Danio rerio
100540067 Meleagris gallopavo
100580013 Nomascus leucogenys
269356 Mus musculus
83959 Homo sapiens
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