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anti-Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) Antibodies

The protein encoded by SLC40A1 is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Additionally we are shipping Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 Kits (30) and Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC40A1 30061 Q9NP59
SLC40A1 53945 Q9JHI9
SLC40A1 170840 Q923U9
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Top anti-Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC40A1 Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:312500 Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Arabidopsis thaliana Rabbit Un-conjugated ELISA, WB sample of a vector (1) and vacuolar membrane fraction of yeast cells expressing AtMTP1 (2)separated on 12 % SDS-PAGE and blotted 1h to PVDF membrane (40 min. at 10 V usingBioRad semidry transfer). Filters were blocked 1h with 5 % low-fat milk powder in TBS-T(0.05% Triton X.100). Membranes were washed 5 times with TBS-T, each time in a freshpolystyrene box and probed with anti-AtMTP1 antibodies (ABIN349669, 1:1000, 1h) andsecondary anti-rabbit (1:2000, 1 h). All steps were performed in RT with agitation. 100 μL Log in to see 5 to 6 Days
$628.32
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with SLC40A1 antibody ABIN239804 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human placenta labeled with Anti SLC40A1/FPN1 Polyclonal Antibody, Unconjugated (ABIN1387819) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse liver lysates probed with Rabbit Anti-SLC40A1 Polyclonal Antibody, Unconjugated  at 1:5000 for 90 min at 37˚C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 11 to 13 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Arabidopsis thaliana Rabbit Un-conjugated WB   100 μg Log in to see 5 to 6 Days
$497.81
Details
Mouse Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

SLC40A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 Antibodies

  1. Arabidopsis thaliana Polyclonal SLC40A1 Primary Antibody for WB - ABIN1110330 : Selote, Samira, Matthiadis, Gillikin, Long: Iron-binding E3 ligase mediates iron response in plants by targeting basic helix-loop-helix transcription factors. in Plant physiology 2015 (PubMed)
    Show all 2 references for ABIN1110330

  2. Arabidopsis thaliana Polyclonal SLC40A1 Primary Antibody for ELISA, WB - ABIN349669 : Kawachi, Kobae, Mimura, Maeshima: Deletion of a histidine-rich loop of AtMTP1, a vacuolar Zn(2+)/H(+) antiporter of Arabidopsis thaliana, stimulates the transport activity. in The Journal of biological chemistry 2008 (PubMed)
    Show all 2 references for ABIN349669

More Antibodies against Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 Interaction Partners

Zebrafish Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) interaction partners

  1. Functional impact of mammalian ferroportin mutations studied in zebrafish.

Arabidopsis thaliana Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) interaction partners

  1. role of IRT1 (show PARP3 Antibodies) in iron uptake

  2. these results suggest that the His-loop of MTP1 acts as a sensor of cytosolic zinc to maintain an essential level in the cytosol and that the dysfunction of the loop results in an uncontrolled accumulation of zinc in the vacuoles of root cells.

  3. Our results reveal a role of SNX1 (show SNX1 Antibodies) for the correct trafficking of IRT1 (show PARP3 Antibodies) and, thus, for modulating the activity of the iron uptake machinery

  4. This work establishes a functional link between the dynamics and the lateral polarity of IRT1 (show PARP3 Antibodies) and the transport of its substrates, and identifies a molecular mechanism driving polar localization of a cell surface protein (show CD28 Antibodies) in plants.

  5. IDF1 directly regulates IRT1 (show PARP3 Antibodies) degradation through its RING-type E3 ligase activity.

  6. Data indicate that steady-state mRNA abundance for three representative Fe homeostasis genes, IRT1 (show PARP3 Antibodies), bHLH39, and FER1 (show FTH1 Antibodies), oscillated in light/dark (LD) cycles or warm/cold environmental cycles.

  7. AtIRT1 transports nicekl (Ni(2 (show VMP1 Antibodies)+)) in roots, and strongly suggest that Ni accumulation is further accelerated by AtIRT1 that is expressed in response to excess Ni.

  8. These data suggest a model in which monoubiquitin-dependent internalization/sorting and turnover keep the plasma membrane pool of IRT1 (show PARP3 Antibodies) low to ensure proper iron uptake and to prevent metal toxicity.

  9. IRT1 and FRO2 genes are upregulated under iron starvation.

  10. Application of the lipoxygenase inhibitor ibuprofene to plants caused an up-regulation of IRT1 (show PARP3 Antibodies) gene expression.

Human Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) interaction partners

  1. The concentration of functional membrane-associated ferroportin is controlled by its ligand, the iron-regulatory hormone hepcidin (show HAMP Antibodies), and fine-tuned by regulatory mechanisms serving iron homeostasis, oxygen utilization, host defense, and erythropoiesis.

  2. Low hepcidin (show HAMP Antibodies) and high ferroportin expression by erythroblasts and macrophages were seen in iron deficiency anemia, while the opposite was true in anemia of chronic disorders.

  3. Erythroblasts from Beta-thalassemia patients showed a significantly reduced expression of total MTP1 protein.

  4. Several family members had hemochromatosis (show HFE Antibodies) and hyperferritinemia associated with a SLC40A1 deletion in exon 5(485_487delTTG) resulting in the deletion of a valine residue (p.V162del). This is the 1st Spanish family reported with this European mutation.

  5. TLR4 (show TLR4 Antibodies) dependent macrophage signaling is controlled via hepcidin (show HAMP Antibodies)-ferroportin1 axis by influencing TLR4 (show TLR4 Antibodies)-lipid raft interactions

  6. study of healthy adults provides further evidence that ferroportin Q248H mutation affects serum ferritin (show FTL Antibodies) concentration in Africans

  7. Single nucleotide polymorphisms in HAMP (show HAMP Antibodies), BMP2 (show BMP2 Antibodies), FTL (show FTL Antibodies) and SLC40A1 genes have phenotype-modifying roles in hereditary hemochromatosis (show HFE Antibodies) type 1.

  8. Decreased expression of hepcidin (show HAMP Antibodies) and ferroportin in hepatitis C patients indicates the importance of hepatocytic iron retention for viral response during pegylated-interferon (show IFNA Antibodies) plus ribavirin treatment.

  9. Data indicate that elevated miR (show MLXIP Antibodies)-492 expression in prostate tumors that resulted in diminished myeloid zinc-finger 1 (MZF-1 (show ZFP42 Antibodies)) and ferroportin (FPN).

  10. we demonstrated that downregulation of FPN1 plays critical roles in promoting myeloma cell growth and bone resorption in multiple myeloma.

Mouse (Murine) Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) interaction partners

  1. The results suggest that physiologic hepcidin (show HAMP Antibodies) levels are insufficient to alter Fpn levels within the retinal pigment epithelium and Muller cells, but may limit iron transport into the retina from vascular endothelial cells.

  2. In Angiotensin II treated mice, duodenal divalent metal transporter-1 (show SLC11A2 Antibodies) and ferroportin expression levels were increased and hepatic hepcidin (show HAMP Antibodies) mRNA expression and serum hepcidin (show HAMP Antibodies) concentration were reduced.

  3. Mice infected with Salmonella typhimurium have increased duodenal expression of the iron exporter ferroportin-1, consistent with increased uptake of dietary iron.

  4. Results suggest that reduction in ferroportin levels in Alzheimer's disease brains are likely associated with cerebral ischaemia, inflammation, loss of neurons due to protein misfolding, senile plaque formation and possibly ageing process itself

  5. Oral iron failed to be utilized by Fpn-KO mice and was retained in enterocytes, irrespective of the iron source. Ferroportin-dependent efflux from enterocytes controls duodenal iron absorption.

  6. Genetic interactions between Cp, Mon1a (show MON1A Antibodies), and the Slc40a1 locus are involved in iron metabolism.

  7. Hypoxia signal, stimulated erythropoietin (show EPO Antibodies), which affected iron absorption by stabilizing duodenal ferroportin.

  8. A model is proposed that suggests that unlike proteases, which are irreversibly bound to activated alpha2M, hepcidin (show HAMP Antibodies) remains labile and available to down-regulate Fpn1.

  9. Nitric oxide up-regulated the expression of ferroportin-1 (Fpn1), the major cellular iron exporter, in mouse and human cells.

  10. Ferroportin transcription following experimentally-induced acute anemia in mice is tissue-specific.

Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1) Antigen Profile

Protein Summary

The protein encoded by this gene is a cell membrane protein that may be involved in iron export from duodenal epithelial cells. Defects in this gene are a cause of hemochromatosis type 4 (HFE4).

Gene names and symbols associated with SLC40A1

  • solute carrier family 40 (iron-regulated transporter), member 1 (slc40a1) antibody
  • solute carrier family 40 (iron-regulated transporter), member 1 (SLC40A1) antibody
  • Fe(2+) transport protein 1 (IRT1) antibody
  • metal tolerance protein 1 short form (ZAT) antibody
  • solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1) antibody
  • solute carrier family 40 member 1 (IREG1) antibody
  • A. THALIANA CATION DIFFUSION FACILITATOR 1 antibody
  • ARABIDOPSIS IRON-REGULATED TRANSPORTER 1 antibody
  • ARABIDOPSIS THALIANA IRON-REGULATED PROTEIN 1 antibody
  • ATCDF1 antibody
  • ATIREG1 antibody
  • ATIRT1 antibody
  • ATMTP1 antibody
  • Dusg antibody
  • F19D11.8 antibody
  • FERROPORTIN 1 antibody
  • Fpn1 antibody
  • HFE4 antibody
  • IREG1 antibody
  • iron-regulated transporter 1 antibody
  • iron regulated 1 antibody
  • MGC82700 antibody
  • MST079 antibody
  • MTP antibody
  • MTP1 antibody
  • Ol5 antibody
  • Pcm antibody
  • Slc11a3 antibody
  • Slc39a1 antibody
  • SLC40A1 antibody
  • T16H5.50 antibody
  • T16H5_50 antibody
  • T19C21.5 antibody
  • T19C21_5 antibody
  • weh antibody
  • ZAT1 antibody
  • zinc transporter of Arabidopsis thaliana antibody
  • ZINC TRANSPORTER OF ARABIDOPSIS THALIANA 1 antibody
  • ZINC TRANSPORTER ZAT antibody

Protein level used designations for SLC40A1

ferroportin-1 , ferroportin1 , iron-regulated transporter , solute carrier family 39 (iron-regulated transporter), member 1 , solute carrier family 40 member 1 , weissherbst , solute carrier family 40 (iron-regulated transporter), member 1 , ferroportin , solute carrier family 40 member 1-like , iron regulated gene 1 , putative ferroportin 1 variant IIIB , solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3 , SLC11A3 iron transporter , duodenal-specific , ferroportin 1 , iron-regulated transporter 1 , metal transporter protein 1 , metal transporting protein 1 , polycythaemia , CAR1 , cell adhesion regulator

GENE ID SPECIES
58153 Danio rerio
423984 Gallus gallus
446661 Xenopus laevis
459821 Pan troglodytes
527023 Bos taurus
713321 Macaca mulatta
785185 Bos taurus
100036732 Xenopus (Silurana) tropicalis
100172551 Pongo abelii
100028485 Monodelphis domestica
100069190 Equus caballus
100474381 Ailuropoda melanoleuca
100588979 Nomascus leucogenys
827713 Arabidopsis thaliana
819293 Arabidopsis thaliana
30061 Homo sapiens
53945 Mus musculus
478837 Canis lupus familiaris
100512076 Sus scrofa
170840 Rattus norvegicus
818427 Arabidopsis thaliana
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