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Solute Carrier Family 45, Member 2 (SLC45A2) ELISA Kits

SLC45A2 encodes a transporter protein that mediates melanin synthesis. Additionally we are shipping SLC45A2 Antibodies (23) and SLC45A2 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC45A2 SLC45A2 51151 Q9UMX9
Anti-Mouse SLC45A2 SLC45A2 22293 P58355
Anti-Rat SLC45A2 SLC45A2 310152  
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More ELISA Kits for SLC45A2 Interaction Partners

Zebrafish Solute Carrier Family 45, Member 2 (SLC45A2) interaction partners

  1. To gain understanding of the role of Slc45a2 and its possible interactions with other proteins involved in melanization, the role of the V-ATPase (show ATP6V1H ELISA Kits) as a melanosomal acidifier, was analyzed.

  2. Zebrafish albino fish are mutant in slc45a2; wild-type slc45a2 mRNA rescued the albino mutant phenotype.

Human Solute Carrier Family 45, Member 2 (SLC45A2) interaction partners

  1. We identitified a single missense substitution in SLC45A2 in 13 families with oculocutaneous albinism.

  2. The reduction of tyrosinase (show TYR ELISA Kits) activity associated with the knockdown of MATP.

  3. The results indicated that the D93N mutation causes OCA4 as a result of loss of MATP transport activity, and that the F374 allele confers significantly lower transport activity than L374.

  4. we propose that natural selection in South Europeans is favoring the allele SLC45A2 374F.

  5. High-resolution array-CGH in patients with oculocutaneous albinism identifies new deletions of the TYR, OCA2, and SLC45A2 genes and a complex rearrangement of the OCA2 gene.

  6. Results show that almost all the African populations located below 16 degrees of latitude are fixed for the 374l allele of SLC45A2 gene.

  7. molecular defects in SLC45A2 gene represent the 3.4% of people with oculocutaneous albinism in this cohort of Italian patients, similar to other Caucasian populations

  8. We examined the association between 12 variants of four pigmentation-related genes (TYR, OCA2, SLC45A2, MC1R) and variations in the melanin index of 456 Japanese females using a multiple regression analysis.

  9. We report four Pakistani albinism mutations, including three SLC45A2 alleles and one 22-nucleotide deletion in TYRP1 (show TYRP1 ELISA Kits).

  10. In South European populations, MC1R red hair color and SCL45A2 p.Phe374Leu variants are strong melanoma risk predictors.

Mouse (Murine) Solute Carrier Family 45, Member 2 (SLC45A2) interaction partners

  1. mRNA expression of SLC45A2 in eyes and skin and of SLC45A3 primarily in the prostate, but also in other tissues, whereas SLC45A4 showed a predominantly ubiquitous expression

SLC45A2 Antigen Profile

Antigen Summary

This gene encodes a transporter protein that mediates melanin synthesis. The protein is expressed in a high percentage of melanoma cell lines. Mutations in this gene are a cause of oculocutaneous albinism type 4, and polymorphisms in this gene are associated with variations in skin and hair color. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC45A2

  • solute carrier family 45, member 2 (SLC45A2) antibody
  • solute carrier family 45, member 2 (slc45a2) antibody
  • solute carrier family 45, member 2 (LOC100228141) antibody
  • solute carrier family 45, member 2 (Slc45a2) antibody
  • 1A1 antibody
  • Aim-1 antibody
  • Aim1 antibody
  • blanc-sale antibody
  • bls antibody
  • Dbr antibody
  • im:7138762 antibody
  • Matp antibody
  • MGC114950 antibody
  • OCA4 antibody
  • SHEP5 antibody
  • SLC45A2 antibody
  • uw antibody

Protein level used designations for SLC45A2

solute carrier family 45, member 2 , membrane-associated transporter protein , membrane associated transporter protein , B , absent in melanoma 1 , alb , albino , oca4 , membrane-associated transporter protein-like , melanoma antigen AIM1 , membrane associated transporter , protein AIM-1 , underwhite , B/AIM-1-like protein , dominant brown , protein underwhite , Membrane-associated transporter protein

431665 Gallus gallus
471584 Pan troglodytes
496798 Xenopus (Silurana) tropicalis
558311 Danio rerio
698246 Macaca mulatta
734429 Xenopus laevis
100228141 Taeniopygia guttata
100406055 Callithrix jacchus
100483846 Ailuropoda melanoleuca
100584203 Nomascus leucogenys
51151 Homo sapiens
22293 Mus musculus
489236 Canis lupus familiaris
606748 Sus scrofa
538746 Bos taurus
310152 Rattus norvegicus
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