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Solute Carrier Family 47, Member 1 (SLC47A1) ELISA Kits

SLC47A1 is located within the Smith-Magenis syndrome region on chromosome 17. Additionally we are shipping Solute Carrier Family 47, Member 1 Antibodies (36) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SLC47A1 55244 Q96FL8
Anti-Rat SLC47A1 SLC47A1 360539 Q5I0E9
Anti-Mouse SLC47A1 SLC47A1 67473 Q8K0H1
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Top Solute Carrier Family 47, Member 1 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 3.9 pg/ml 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

Top referenced Solute Carrier Family 47, Member 1 ELISA Kits

  1. Human SLC47A1 ELISA Kit for Sandwich ELISA - ABIN823375 : Lee, Lee, Kim, Lee, Jun, Lee: Multidrug and toxic compound extrusion protein-1 (MATE1/SLC47A1) is a novel flavonoid transporter. in Journal of agricultural and food chemistry 2014 (PubMed)

More ELISA Kits for Solute Carrier Family 47, Member 1 Interaction Partners

Rabbit Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. MATE1 has an external COOH terminus, consistent with a 13-helix topology, which may influence transporter turnover.

Human Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. MATE1 rs2289669 may be a significant determinant in the renal clearance of metformin in the case of transporter-mediated drug interactions

  2. Disease progression according to RECIST was also more frequent in carriers of at least one polymorphic MATE1 A-allele (44%) as compared with homozygous carriers of the wild-type G-allele (12.5%) (P=0.07). OCT1 (show POU2F1 ELISA Kits) and MATE1 were not associated with PFS.

  3. MATE1 sequesters organic cations within an intracellular compartment that has no influence on secretion in renal proximal tubules.

  4. SLC47A1 rs2289669 G>A variants improve the glucose-lowering effect of metformin through slowing its excretion in type 2 diabetes populations.

  5. MRNA levels of multidrug and toxin extrusion protein 1 (MATE1 or SLC47A1, encoded by 1 of the 11 genes) were significantly lower in patients with FILI.

  6. MATE1 is a membrane transporter for quercetin.MATE1 was highly expressed in peroxisomes and the endoplasmic reticulum as well as in plasma membranes in the liver and intestine.

  7. ADMA and L-arginine (show GATM ELISA Kits) are substrates of human CAT2A, CAT2B, OCT2 and MATE1. Transport kinetics of CAT2A, CAT2B, and OCT2 indicate a low affinity, high capacity transport, which may be relevant for renal and hepatic elimination of ADMA or L-arginine (show GATM ELISA Kits)

  8. The results confirmed that OAT1 (show KCNK3 ELISA Kits), OAT3 (show SLC22A8 ELISA Kits), OCT2, MATE1, and MATE2-K (show SLC47A2 ELISA Kits) were coexpressed in tubular epithelial cells.

  9. Decreasing expression of OCT3 (show POU5F1 ELISA Kits) and MATE1 in human placenta indicates these transporters may play a role in fetal protection preferentially at earlier stages of gestation.

  10. The 808G>T single-nucleotide polymorphism in OCT2 ameliorated cisplatin-induced nephrotoxicity without alteration of disposition, whereas the rs2289669 G>A single-nucleotide polymorphism in MATE1 had no effect on cisplatin toxicity.

Mouse (Murine) Solute Carrier Family 47, Member 1 (SLC47A1) interaction partners

  1. Mate1 mRNA expression was decreased in mice with either the ob/ob model or the methionine/choline deficiency model of nonalcoholic steatohepatitis.

  2. MATE1 was highly expressed in peroxisomes and the endoplasmic reticulum as well as in plasma membranes in the liver and intestine.

  3. [(11)C]Metformin may be useful as a PET probe to non-invasively study the in vivo function of hepatobiliary transport and drug-drug interactions, mediated by MATE1 in future clinical investigations.

  4. Twelve transmembrane helices form the functional core of mammalian MATE1 (multidrug and toxin extruder 1) protein.

  5. Homozygous MATE1 variant could be one of the risk factors for metformin-induced lactic acidosis.

  6. MATE1 mediates the efflux of cisplatin and is involved in cisplatin-induced nephrotoxicity.

  7. mMATE1 is polyspecific H(+)/(organic cation)OC exchanger. Unexpectedly wide distribution of mMATE1 suggests involvement in diverse biological functions other than excretion of OCs from the body. (Multidrug and toxin extrusion 1, MATE1)

  8. mMATE1b is a functional variant of mMATE1 and seems to be the true counterpart to other MATE1 transporters

  9. MATE1 mRNA levels were highest in the kidney, where male expression was higher than female.

  10. This is the first report to demonstrate an essential role of MATE1 in systemic clearance of metformin.

Solute Carrier Family 47, Member 1 (SLC47A1) Antigen Profile

Antigen Summary

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function.

Gene names and symbols associated with SLC47A1

  • solute carrier family 47, member 1 (SLC47A1) antibody
  • solute carrier family 47, member 1 (slc47a1) antibody
  • solute carrier family 47 (multidrug and toxin extrusion), member 1 (SLC47A1) antibody
  • solute carrier family 47, member 1 (LOC100220385) antibody
  • MATE1 (LOC100125995) antibody
  • solute carrier family 47 (multidrug and toxin extrusion), member 1 (Slc47a1) antibody
  • solute carrier family 47, member 1 (Slc47a1) antibody
  • 1300013J15Rik antibody
  • AI036982 antibody
  • DKFZp469B1821 antibody
  • MATE1 antibody
  • mMATE1 antibody
  • RGD1311123 antibody
  • SLC47A1 antibody
  • zgc:113362 antibody

Protein level used designations for SLC47A1

solute carrier family 47, member 1 , multidrug and toxin extrusion protein 1 , MATE-1 , solute carrier family 47 member 1 , hMATE-1 , multidrug and toxin extrusion 1 , H+/organic cation antiporter variant 1 , H+/organic cation antiporter variant 2 , rMATE-1 , mMATE-1

GENE ID SPECIES
489529 Canis lupus familiaris
541497 Danio rerio
616474 Bos taurus
741988 Pan troglodytes
100171505 Pongo abelii
100220385 Taeniopygia guttata
100125995 Oryctolagus cuniculus
55244 Homo sapiens
360539 Rattus norvegicus
67473 Mus musculus
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