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Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment (By similarity).. Additionally we are shipping and and many more products for this protein.
a model in which heme is translocated across membranes facilitated by conserved amino acids positioned on the exoplasmic, cytoplasmic, and transmembrane regions of HRG-1-related proteins.
hrg-1 is a heme-responsive element that mediates transcriptional regulation in Caenorhabditis elegans
identification of HRG-1 protein in C. elegans; these proteins are essential for haem homeostasis and normal development
These results reveal HRG1 as the long-sought heme transporter for heme-iron recycling in macrophages and suggest that genetic variations in HRG1 could be modifiers of human iron metabolism.
HRG-1 may represent a novel target for selectively disrupting V-ATPase (show ATP6V1H ELISA Kits) activity and the metastatic potential of cancer cells.
SLC48A1 is a target gene of the BACH1 (show BACH1 ELISA Kits) transcription factor according to ChIP-seq analysis in HEK (show EPHA3 ELISA Kits) 293 cells.
HRG-1 regulates V-ATPase (show ATP6V1H ELISA Kits) activity, which is essential for endosomal acidification, heme binding, and receptor trafficking in mammalian cells.
Human and worm proteins localize together, and bind and transport haem, thus establishing an evolutionarily conserved function for HRG-1.
Heme transporter that regulates intracellular heme availability through the endosomal or lysosomal compartment (By similarity).
heme transporter HRG1
, heme-responsive gene 1 protein homolog
, solute carrier family 48 member 1
, Heme-responsive gene 1 protein homolog