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Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteins (SLC5A1)

SLC5A1 encodes a member of the sodium-dependent glucose transporter (SGLT) family. Additionally we are shipping Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Antibodies (108) and Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC5A1 6523 P13866
SLC5A1 20537 Q8C3K6
SLC5A1 25552 P53790
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Top Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

SLC5A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine) ,

Rat (Rattus)

Top referenced Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 Proteins

  1. Human SLC5A1 Protein expressed in Wheat germ - ABIN1320482 : Huang, Hsu, Huang, Chen, Hsiao, Zhang, Fidler, Hung: Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis. in American journal of translational research 2013 (PubMed)

More Proteins for Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Interaction Partners

Horse (Equine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. SGLT1 expression is enhanced, with time, 2-fold in the duodenum and 3.3-fold in the ileum for horses switched, gradually over a 2-month period, from low (<1.0 g/kg bwt/day) to high hCHO (6.0 g/kg bwt/day) diets of known composition.

Human Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Compound K induces SGLT1 expression and glucose uptake in differentiated intestinal Caco-2 cells.

  2. Data demonstrate a role for Per1 in the transcriptional regulation of NHE3 (show SLC9A3 Proteins) and SGLT1 in the kidney.

  3. Cardiac SGLTs, possibly SGLT1 in particular, appear to provide an important protective mechanism against ischemia-reperfusion injury by replenishing ATP stores in ischemic cardiac tissues.

  4. CREB (show CREB1 Proteins) activation is essential for EGF (show EGF Proteins)-induced SGLT1 gene expression.

  5. SGLT1 or GLUT2 (show SLC2A2 Proteins) interact with the cytoskeleton in the intestinal epithelium during hexose absorption.

  6. SGLT1 mRNA and GLUT2 (show SLC2A2 Proteins) mRNA expression are reduced significantly in CACo-2 cells exposed to berry extracts.

  7. SGLT1 and GLUT5 expression in the plasma membrane is regulated by TNFalpha (show TNF Proteins), leading to alteration on sugar transport, suggesting that TNFalpha (show TNF Proteins) could be a physiological local regulator of nutrient absorption in response to an intestinal inflammatory status.

  8. Delphinidin-3-glucoside protects against oxidized low-density lipoprotein-induced mitochondrial dysfunction in vascular endothelial cells via the sodium-dependent glucose transporter SGLT1.

  9. Data indicate that IGF-1R (show IGF1R Proteins) and SGLT1 interact in HEK293 and MCF7 cells, and IGF-1R (show IGF1R Proteins) siRNA transfection results in down-regulation of SGLT1.

  10. Results suggest that the use of MAP17 (show PDZK1IP1 Proteins) and SGLT1 markers may identify patients who are likely to exhibit a better response to treatments that boost oxidative stress in other cancer types.

Mouse (Murine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Enhanced cerebral sodium-glucose transporter function mediated by post-ischemic hyperglycemia exacerbates the development of cerebral ischemic neuronal damage.

  2. These findings support the involvement of SGLT1 in post-oral glucose and MDG (show CACNA1S Proteins) conditioning.

  3. Compound K upregulates SGLT1 expression in vivo in mice.

  4. Studied leptin (show LEP Proteins) and CST (show CORT Proteins) modulation of SGLT1 expression in hyperleptinemic type 2 diabetic mice.

  5. Cardiac knockdown of SGLT1 in a murine model of PRKAG2 (show PRKAG2 Proteins) cardiomyopathy attenuates the disease phenotype, implicating SGLT1 in the pathogenesis. Overexpression of SGLT1 causes pathologic cardiac hypertrophy and left ventricular failure that is reversible.

  6. In conclusion, SPAK (show STK39 Proteins) is a powerful negative regulator of SGLT1 protein abundance in the cell membrane and thus of electrogenic glucose transport.

  7. role of SGLT1 and GLUT2 (show SLC2A2 Proteins) in intestinal glucose transport and sensing

  8. Improved glycemic control in mice lacking Sglt1 and Sglt2 (show SLC5A2 Proteins).

  9. Data suggest that the absence of intestinal microbiota alters expression of (i.e., up-regulates) Sglt1 and Tas1r3 (show TAS1R3 Proteins) in proximal small intestine, factors associated with increased consumption of nutritive sweet solutions.

  10. SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion.

Pig (Porcine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. The segmental differences in porcine glucose transport characteristics may be based on direct or indirect modulations of SGLT1 activity.

  2. The increased expression of SGLT1 in the jejunum by phytase supplementation implies that phytase alleviated the negative effects of phytic acid partly through increased expression of SGLT1.

  3. neonates have high intestinal apical SGLT1 uptake activity by abundantly expressing SGLT1 protein in epithelia and on apical membrane along the entire crypt-villus axis in association with enhanced protein translational control mechanisms in crypt cells.

  4. In accord with a rise in methyl alpha-D-glucopyranoside uptake activity, the mRNA and protein levels of SGLT1 were apparently up-regulated in the presence of apoE3

  5. Expression of SLGT1 was evaluated in LLC-PK1 cells grown on porous membranes for the development of an artificial kidney.

Cow (Bovine) Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) interaction partners

  1. Na+-dependent glucose cotransporter(SGLT)1 mRNA was most abundant in bovine intestine, at intermediate levels in bovine kidney, and at lower levels in bovine mammary gland, liver, and lung.

Solute Carrier Family 5 (Sodium/glucose Cotransporter), Member 1 (SLC5A1) Protein Profile

Protein Summary

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SLC5A1

  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (SLC5A1)
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (slc5a1)
  • solute carrier family 5 (sodium/glucose cotransporter), member 1 (Slc5a1)
  • solute carrier family 5 (sodium/glucose cotransporter), member 10 (SLC5A10)
  • D22S675 protein
  • NAGT protein
  • Sglt1 protein
  • SGLT5 protein
  • SLC5A1 protein
  • zgc:66074 protein
  • zgc:85782 protein

Protein level used designations for SLC5A1

Na+/glucose co-transporter , sodium/glucose cotransporter 1 , SGLT1 , solute carrier family 5 (sodium/glucose cotransporter), member 1 , solute carrier family 5, member 1 , sodium/glucose cotransporter 1-like , Na+/glucose cotransporter 1 , high affinity sodium-glucose cotransporter , Na(+)/glucose cotransporter 1 , sodium glucose cotransporter 1 , sodium-glucose cotransporter 1 , solute carrier family 5 member 1 , solute carrier family 5, member alpha 1 , Na+/glucose cotransporter , Solute carrier family 5, member alpha 1 (Na+/glucose cotransporter) , sodium-glucose cotransporter-like 1 , cortical sodium-D-glucose cotransporter , sodium/glucose cotransporter-like protein , SGLT-1 , Na(+)/glucose cotransporter 5 , sodium/glucose cotransporter 5 , solute carrier family 5 member 10

GENE ID SPECIES
100033952 Equus caballus
393654 Danio rerio
458779 Pan troglodytes
717070 Macaca mulatta
100137235 Papio anubis
100435495 Pongo abelii
100593847 Nomascus leucogenys
6523 Homo sapiens
20537 Mus musculus
397113 Sus scrofa
25552 Rattus norvegicus
492299 Canis lupus familiaris
282361 Bos taurus
100009262 Oryctolagus cuniculus
492300 Ovis aries
395496 Gallus gallus
497235 Sus scrofa
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