anti-Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) Antibodies

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC5A8 216225 Q8BYF6
SLC5A8 160728 Q8N695
SLC5A8 500820  
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Top anti-SLC5A8 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-SLC5A8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>OVCAR-3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western Blot: SLC5A8 Antibody [NBP1-62527] - OVCAR-3 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8 to 11 Days
$447.56
Details
Mouse Rabbit Un-conjugated WB Mouse Slc5a8 Antibody (C-term) (ABIN1881812) western blot analysis in mouse bladder tissue lysates (35 µg/lane). This demonstrates the Mouse Slc5a8 antibody detected the Mouse Slc5a8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated CyTOF, FACS Detection of SLC5A8/SMCT1 in HEK293 Human Cell Line Transfected with Human SLC5A8/SMCT1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 and eGFP was stained with either (A) Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$278.25
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-SLC5A8 Polyclonal Antibody, Unconjugated (ABIN762521) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Mouse Allophycocyanin FACS Detection of SLC5A8/SMCT1 in MCF-7 Human Cell Line by Flow Cytometry. MCF-7 human breast cancer cell line was stained with Mouse Anti-Human SLC5A8/SMCT1 APC-conjugated Monoclonal Antibody. Detection of SLC5A8/SMCT1 in HEK293 Human Cell Line Transfected with Human SLC5A8/SMCT1 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 and eGFP was stained with either (A) Mouse Anti-Human SLC5A8/SMCT1 APC-conjugated Monoclonal Antibody. 25 Tests Log in to see 8 to 9 Days
$220.50
Details
Human Mouse Alexa Fluor 647 FACS   0.1 mg Log in to see 10 to 13 Days
$447.56
Details
Human Mouse Alexa Fluor 488 FACS   0.1 mg Log in to see 10 to 13 Days
$447.56
Details
Human Mouse Alexa Fluor 750 FACS   0.1 mg Log in to see 10 to 13 Days
$447.56
Details

SLC5A8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SLC5A8 Antibodies

  1. Human Polyclonal SLC5A8 Primary Antibody for WB - ABIN2781721 : Zhang, Bao, Yang, Wu, Yu, Huang, Sun, Zheng, Li: Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells. in The international journal of biochemistry & cell biology 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal SLC5A8 Primary Antibody for WB - ABIN4892821 : Nedjadi, Moran, Al-Rammahi, Shirazi-Beechey: Characterization of butyrate transport across the luminal membranes of equine large intestine. in Experimental physiology 2014 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) Polyclonal SLC5A8 Primary Antibody for WB - ABIN1881812 : Cresci, Thangaraju, Mellinger, Liu, Ganapathy: Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8. in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010 (PubMed)

More Antibodies against SLC5A8 Interaction Partners

Mouse (Murine) Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) interaction partners

  1. Slc5a8 is an obligatory link between dietary fibre and mucosal immune system via the bacterial metabolite butyrate and that this transporter is a conditional tumour suppressor in colon linked to dietary fibre content.

  2. Data indicate oncogenic HRAS (HRAS (show HRAS Antibodies)(G12V)) as a potent mediator of SLC5A8 silencing in human nontransformed normal mammary epithelial cell lines and in mouse mammary tumors through DNMT1 (show DNMT1 Antibodies).

  3. Efficacy of LP or their secreted soluble factors to stimulate SMCT1 expression and function and to counteract the inhibitory effects of TNF-alpha (show TNF Antibodies) on butyrate absorption could have potential therapeutic value.

  4. butyrate and propionate block the generation of dendritic cells from bone marrow stem cells, since Slc5a8 transports butyrate and propionate into cells, and these two bacterial metabolites inhibit histone deacetylases

  5. Sodium-coupled electrogenic transport of pyroglutamate (5-oxoproline) via SLC5A8, a monocarboxylate transporter.

  6. In conventional mice with normal bacterial colonization of the intestinal tract, GPR109A and SLC5A8 are expressed on the apical membrane of epithelial cells lining the ileum and colon.

  7. CDX1 (show CDX1 Antibodies) and CDX2 (show CDX2 Antibodies) bind the promoter region of SLC5A8 and up-regulate its expression in cultured cells and in colonic epithelium.

  8. slc5a8 is expressed abundantly in the kidney and plays a role in the active reabsorption of lactate

  9. SMCT functions not only as a Na+-coupled transporter for short-chain fatty acids and lactate but also as a Na+-coupled transporter for the water-soluble vitamin nicotinic acid.

  10. Data describe the cellular localization of Slc5a8 in the murine gastrointestinal tract and kidney by in situ hybridization and immunohistochemistry.

Human Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8) interaction partners

  1. Human SMCT1 is regulated by insulin (show INS Antibodies) and SGK1 (show SGK1 Antibodies).

  2. Data suggest positive correlation between BMI (body mass index)/waist circumference in morbidly obese or obese subjects and jejunal mucosa mRNA abundance of SMCT1; BMI was not significantly correlated with mRNA abundance for glucose transporters SGLT1 and GLUT2 or the low-affinity short-chain fatty acid/monocarboxylate transporter SMCT2.

  3. Underexpression of SLC5A8 is associated with hepatocellular carcinoma.

  4. Data suggest that SLC5A8, SLC5A5 (sodium-iodide symporter (show SLC5A5 Antibodies)), and SLC26A4 (pendrin (show SLC26A4 Antibodies)), the 3 known iodide transporters, are important in breast tissue metabolism in lactation and in breast neoplasms. [REVIEW]

  5. Gene silencing of SLC5A8 by hypermethylation was associated with poor prognosis in cases of node-negative stage I and II lung adenocarcinoma.

  6. Data indicate oncogenic HRAS (HRAS (show HRAS Antibodies)(G12V)) as a potent mediator of SLC5A8 silencing in human nontransformed normal mammary epithelial cell lines and in mouse mammary tumors through DNMT1 (show DNMT1 Antibodies).

  7. These results suggest that DNA methylation (show HELLS Antibodies) in the SLC5A8 promoter region may suppress the expression of SLC5A8 in lung tumor.

  8. SLC5A8 suppresses tumour progression through depletion of survivin (show BIRC5 Antibodies) without involving its transport function

  9. SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma.

  10. SLC5A8 has a role in prostate cancer risk and aggressiveness

SLC5A8 Antigen Profile

Protein Summary

SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002

Gene names and symbols associated with SLC5A8

  • solute carrier family 5 (iodide transporter), member 8 (Slc5a8) antibody
  • solute carrier family 5 (iodide transporter), member 8 (SLC5A8) antibody
  • solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 (SLC5A8) antibody
  • solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 (Slc5a8) antibody
  • AIT antibody
  • RGD1564146 antibody
  • SMCT antibody
  • SMCT1 antibody

Protein level used designations for SLC5A8

apical iodide transporter , putative , electrogenic sodium monocarboxylate cotransporter , sodium-coupled monocarboxylate transporter 1 , solute carrier family 5 member 8 , sodium-dependent monocarboxylate cotransporter , apical iodide transporter , sodium iodide-related cotransporter , solute carrier family 5 (iodide transporter), member 8

GENE ID SPECIES
216225 Mus musculus
417932 Gallus gallus
482626 Canis lupus familiaris
615734 Bos taurus
160728 Homo sapiens
500820 Rattus norvegicus
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