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Solute Carrier Family 6 (Neurotransmitter Transporter, Betaine/GABA), Member 12 (SLC6A12) ELISA Kits

Transports betaine and GABA. Additionally we are shipping SLC6A12 Antibodies (25) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC6A12 SLC6A12 14411  
Anti-Rat SLC6A12 SLC6A12 50676 P48056
Anti-Human SLC6A12 SLC6A12 6539 P48065
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More ELISA Kits for SLC6A12 Interaction Partners

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Betaine/GABA), Member 12 (SLC6A12) interaction partners

  1. Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13 (show SLC6A13 ELISA Kits)) gene in mice leads to changes in liver and brain taurine contents.

  2. This study suggests that BGT1 plays its main role in the liver, thereby complementing other betaine-transporting carrier proteins (e.g., slc6a20 (show SLC6A20 ELISA Kits)) that are predominantly expressed in the small intestine or kidney rather than the liver.

  3. Mice lacking exons 3-5 of the BGT1 gene have normal development & show seizure susceptibility indistinguishable from wild-type in a variety of seizure threshold models. This does not support a role for BGT1 in the control of seizure susceptibility.

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Betaine/GABA), Member 12 (SLC6A12) interaction partners

  1. T40 may be important for the trafficking and insertion of BGT1 in the plasma membrane

  2. JAK2 (show JAK2 ELISA Kits) is a novel regulator of the GABA transporter BGT1.

  3. This study found that rs216250 of SLC6A12 was correlated with the Scale for the Assessment of Negative Symptoms (SANS (show USH1G ELISA Kits)) scores.

  4. Results showed that two polymorphisms and a haplotype in SLC6A12, were significantly associated with AIA after multiple testing corrections.

  5. The primary structure of BGT-1 predicts two putative phosphorylation sites for the Ca2 (show CA2 ELISA Kits)+/diacylglycerol-dependent protein kinase (show CDK7 ELISA Kits) (PKC), which regulates BGT-1 function by phosphorylation events in a transport system expressed in cultured astrocytoma cells.

  6. BGT-1 is expressed from mRNA and transports GABA in platelets.

SLC6A12 Antigen Profile

Antigen Summary

Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.

Gene names and symbols associated with SLC6A12

  • solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 (SLC6A12) antibody
  • solute carrier family 6 (neurotransmitter transporter, GABA), member 13 (slc6a13) antibody
  • solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 (slc6a12) antibody
  • solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 (Slc6a12) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 12 (Slc6a12) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 12 (SLC6A12) antibody
  • BGAT antibody
  • BGT-1 antibody
  • BGT1 antibody
  • Gabt2 antibody
  • gat-2 antibody
  • Gat1 antibody
  • GAT2 antibody
  • MGC145946 antibody
  • RNU28927 antibody
  • slc6a12 antibody
  • VGAT antibody

Protein level used designations for SLC6A12

sodium- and chloride-dependent betaine transporter , solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 , solute carrier family 6 (neurotransmitter transporter, GABA), member 13 , sodium- and chloride-dependent betaine transporter-like , GAT-2 , Na(+)/Cl(-) betaine/GABA transporter , gamma-aminobutyric acid (GABA-A) transporter 2 , sodium- and chloride-dependent GABA transporter 2 , solute carrier family 6 member 12 , Betain-GABA transporter , Na+- and Cl- dependent betaine transporter , betaine gamma-amino-n-butyric acid transporter , Na and Cl dependent betaine transporter , Betaine/GABA transporter 1 , GABA transporter 1 , vesicular GABA transporter , betaine/GABA transporter-1 , gamma-aminobutyric acid transporter

GENE ID SPECIES
514339 Bos taurus
705780 Macaca mulatta
780375 Xenopus (Silurana) tropicalis
100016965 Monodelphis domestica
100396430 Callithrix jacchus
100512716 Sus scrofa
100551873 Anolis carolinensis
14411 Mus musculus
404013 Canis lupus familiaris
100009202 Oryctolagus cuniculus
467192 Pan troglodytes
50676 Rattus norvegicus
6539 Homo sapiens
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