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anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) Antibodies

SLC6A3 encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. Additionally we are shipping SLC6A3 Kits (47) and SLC6A3 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC6A3 13162 Q61327
SLC6A3 6531 Q01959
SLC6A3 24898 P23977
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Top anti-SLC6A3 Antibodies at antibodies-online.com

Showing 10 out of 108 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated EIA, WB Staining of Human Substantia nigra lysate (35µg protein in RIPA buffer) using SLC6A3 antibody at 1 µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (fro), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Mouse Mouse Un-conjugated ICC, IF, WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Rabbit Un-conjugated IF (cc) RSC96 cells probed with Rabbit Anti-DAT/Dopamine transporter Polyclonal Antibody . 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC6A3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate WB Suggested Anti-SLC6A3  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated DB, IHC (fro), WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with SLC6A3 antibody ABIN298105 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

SLC6A3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SLC6A3 Antibodies

  1. Mouse (Murine) Monoclonal SLC6A3 Primary Antibody for ICC, IF - ABIN1169684 : Cremona, Matthies, Pau, Bowton, Speed, Lute, Anderson, Sen, Robertson, Vaughan, Rothman, Galli, Javitch, Yamamoto: Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT. in Nature neuroscience 2011 (PubMed)
    Show all 3 references for ABIN1169684

  2. Human Polyclonal SLC6A3 Primary Antibody for EIA, WB - ABIN954827 : Mazei-Robison, Bowton, Holy, Schmudermaier, Freissmuth, Sitte, Galli, Blakely: Anomalous dopamine release associated with a human dopamine transporter coding variant. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 (PubMed)

  3. Human Polyclonal SLC6A3 Primary Antibody for IF (cc) - ABIN733373 : Ni, Hu, Ren, Luo, Li, Wan, Su: Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimensional culture. in PLoS ONE 2013 (PubMed)

  4. Human Polyclonal SLC6A3 Primary Antibody for IHC (fro), WB - ABIN372614 : Kish, Kalasinsky, Derkach, Schmunk, Guttman, Ang, Adams, Furukawa, Haycock: Striatal dopaminergic and serotonergic markers in human heroin users. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001 (PubMed)

More Antibodies against SLC6A3 Interaction Partners

Rhesus Monkey Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. DNA of the impulsive but not the calm subjects was methylated at one DAT SNP.

  2. nitrative damage accumulates in midbrain neurons with age; The capacity of a dopamine neuron to accumulate more cytosolic DA, as inferred from DA transporter expression, is related to accumulation of nitrative damage

Caenorhabditis elegans (C. elegans) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. Endogenous dopamine actions in C. elegans are tightly regulated by synaptic DAT-1.

  2. loss of UNC-64/DAT-1 interactions leads to enhanced synaptic dopamine release

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. Data suggest that environment pollutants methylmercury and 1-methyl-4-phenylpyridinium decrease release of dopamine from dopaminergic neurons; this mechanism involves down-regulation of expression of Slc6a3.

  2. This study show that Dopamine transporter is enriched in filopodia and induces filopodia formation.

  3. The sigma-1R deficiency through suppressing NR2B (show GRIN2B Antibodies) function and DAT expression can reduce MPTP (show PTPN2 Antibodies)-induced death of dopaminergic neurons and parkinsonism.

  4. DAT gene knockout in mice results dendritic spine loss in pyramidal neurons in the CA1 (show CA1 Antibodies) field of the hippocampus.

  5. Results show that moderate increases in DAT function cause spontaneous dopaminergic cell loss, oxidative stress and fine motor impairment that is reversed by l-DOPA treatment

  6. Chronic and acute reductions of DAT functioning in mice impaired decision-making.

  7. These results demonstrate that the presence of the N-terminal tag leads to impaired DAT protein expression in vivo due in part to improper trafficking of the tagged transporter.

  8. studies demonstrate an in vivo functional impact of the DAT Val559 variant, providing support for the ability of DAT dysfunction to impact risk for mental illness.

  9. The data of this study imply that individual differences in DAT expression (either genetically or pharmacologically induced) may affect susceptibility to addiction of different types of psychostimulants.

  10. findings support the idea that altered DAT and VMAT2 (show Slc18a2 Antibodies) expression affect age-related changes in dopaminergic function.

Cow (Bovine) Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. DAT-mediated dopamine uptake plays a role in the absorption and distribution of dopamine following intranasal administration

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3) interaction partners

  1. Study failed to observe a significant association of the SLC6A3 40-base pair variable number of tandem repeats polymorphism (rs28363170) with cognitive function in healthy adults

  2. the 3'-UTR (show UTS2R Antibodies) VNTR polymorphism is significantly associated with smoking cessation, and smokers with one or more 9-repeat alleles have a 17% higher probability of smoking cessation than smokers carrying no such allele. [meta-analysis]

  3. high SLC6A3 expression in Clear cell renal cell carcinoma (show MOK Antibodies) tissue was correlated with a shorter period of recurrence-free survival following surgery.

  4. Children without the haplotypes associated with the reduced SLC6A3 gene expression and thus lower dopamine functioning appeared to demonstrate altered levels of effortful control as a function of maternal parenting quality.

  5. Computational study providse novel insights into the role of collective dynamics in functionally relevant state-to-state transitions in DAT, at a level of atomistic detail

  6. Higher levels of maternal depressive symptoms predicted reduced cortisol flexibility across challenges for infants with at least one A1 allele of DRD2 (show DRD2 Antibodies) and infants with the 10/10 genotype of SLC6A3

  7. 3'-UTR (show UTS2R Antibodies) variable number tandem repeat associated with post-traumatic stress disorder [meta-analysis]

  8. The NET and DAT N Termini Are Critical for Internalization and Postendocytic Sorting.

  9. the putative involvement of DAT1 and DRD4 (show DRD4 Antibodies) genes in the aetiology of Attention-deficit hyperactivity disorder with a main role in modulation of key dimensions of the disorder

  10. we did not find any significant associations of COMT (show COMT Antibodies) or SLC6A3 with inhibitory performance or impulsivity

SLC6A3 Antigen Profile

Protein Summary

This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.

Gene names and symbols associated with SLC6A3

  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (SLC6A3) antibody
  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (slc6a3) antibody
  • Protein DAT-1 (dat-1) antibody
  • solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (Slc6a3) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 3 (SLC6A3) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 3 (Slc6a3) antibody
  • DAT antibody
  • DAT1 antibody
  • PKDYS antibody
  • SLC6A3 antibody

Protein level used designations for SLC6A3

dopamine transporter variant II , sodium-dependent dopamine transporter , solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 , sodium-dependent dopamine transporter-like , DA transporter , dopamine transporter 1 , solute carrier family 6 member 3 , DAT , solute carrier family 6, member 3

GENE ID SPECIES
574143 Macaca mulatta
609304 Canis lupus familiaris
750842 Pan troglodytes
100054747 Equus caballus
100393968 Callithrix jacchus
100478402 Ailuropoda melanoleuca
100488824 Xenopus (Silurana) tropicalis
176304 Caenorhabditis elegans
13162 Mus musculus
788410 Bos taurus
6531 Homo sapiens
24898 Rattus norvegicus
Selected quality suppliers for anti-SLC6A3 (SLC6A3) Antibodies
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