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anti-Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) Antibodies

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC6A1 232333 P31648
SLC6A1 79212 P23978
SLC6A1 6529 P30531
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SLC6A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) ,


Rat (Rattus) ,


Human , ,
,

Top referenced anti-Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 Antibodies

  1. Human Polyclonal SLC6A1 Primary Antibody for ELISA, WB - ABIN1451643 : Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: The DNA sequence, annotation and analysis of human chromosome 3. ... in Nature 2006 (PubMed)

  2. Mouse (Murine) Polyclonal SLC6A1 Primary Antibody for IHC (fro), WB - ABIN372646 : Minelli, Brecha, Karschin, DeBiasi, Conti: GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. in The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 (PubMed)

  3. Chicken Polyclonal SLC6A1 Primary Antibody for IHC, WB - ABIN2781581 : Gotlib, Joormann, Minor, Hallmayer: HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression. in Biological psychiatry 2008 (PubMed)

More Antibodies against Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 Interaction Partners

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) interaction partners

  1. Results demonstrated that GAT-1-/- mice have phenotypes of hyperactivity, impaired sustained attention and learning deficiency, and the performance of GAT-1-/- mice is similar to ADHD symptoms.

  2. Results suggest that the excessive GAT-1 and GlyT-1 (show GLYT1 Antibodies)/2 heterotransporter-mediated Glu (show GCG Antibodies) release, in the spinal cord of SOD1 (show SOD1 Antibodies)(G93A) mice, is due to the heterotransporter over-expression at the nerve terminal membrane, promoted by the excessive Glu (show GCG Antibodies) exocytosis

  3. Results demonstrate that high-affinity activation by GABA of GAT1 transporters provokes release of [3H]GABA from nerve terminals by different mechanisms

  4. these data show that during paclitaxel-induced neuropathic pain there is significant increase in GAT-1 expression in the ACC. GAT-1 is the main transporter of GABA from the synapse

  5. Development of GABA-removal system and its relationship to development of GABAergic networks studied by examination of changes in GAT-1 and GAT-3 (show SLC6A13 Antibodies) expression and localization in embryonic and postnatal mouse spinal cord

  6. GAT1 plays a critical role in the regulation of rapid eye movement (REM (show REM1 Antibodies)) sleep and homeostasis of non-REM (show REM1 Antibodies) sleep.

  7. results suggest that GAT1 ko mouse is a new animal model for ADHD studying and GAT1 may be a new target to treat ADHD

  8. We failed to provide proof-of-concept evidence that lower PV and GAT1 expression in schizophrenia are a consequence of lower GAD67 (show GAD1 Antibodies) expression

  9. Results suggest that a moderate reduction in GAT1 activity causes the enhancement of learning and memory in mice.

  10. the terminal sialic acid of N-linked oligosaccharides of GAT1 plays a crucial role in the gamma aminobutyric acid transport process

Human Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) interaction partners

  1. Results show that SLC6A1 minor genotypes/alleles were protective against risk for alcoholism in 3 ethnically diverse cohorts.

  2. Genome-wide significant associations were highly biological plausible, including associations within GABA transporter 1, SLC6A1 (solute carrier (show SERTAD2 Antibodies) family 6, member 1), and exonic hits in LOC100129340 (mitofusin-1 (show MFN1 Antibodies)-like

  3. targeted resequencing of 644 individuals with epileptic encephalopathies led to the identification of six SLC6A1 mutations in seven individuals, all of whom have epilepsy with myoclonic-atonic seizures (MAE).

  4. 3p25.3 microdeletion of GABA transporters SLC6A1 and SLC6A11 (show SLC6A11 Antibodies) results in intellectual disability, epilepsy and stereotypic behavior.

  5. Cysteine mutagenesis of GAT-1 pointed to conformationally sensitive proximity of extracellular loops 2 and 4 in this protein.

  6. The aromatic and charge pairs of the thin extracellular gate of the GABA transporter GAT-1 are differently impacted by mutation.

  7. a functional interaction of the external and internal gates of GAT-1 is essential for transport

  8. TM10 of GAT-1 lines an accessibility pathway from the extracellular space into the binding pocket and plays a role in the opening and closing of the extracellular transporter gate.

  9. GABA Transporter Mutagenesis Database (GATMD), a web-accessible, relational database of manually annotated biochemical, functional and pharmacological data reported on GAT1.

  10. A glutamine residue conserved in the neurotransmitter:sodium:symporters is essential for the interaction of chloride with the GABA transporter GAT-1.

Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) Antigen Profile

Protein Summary

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009

Gene names and symbols associated with SLC6A1

  • GABA neurotransmitter transporter 1 (slc6a1) antibody
  • solute carrier family 6 (neurotransmitter transporter, GABA), member 1 (Slc6a1) antibody
  • solute carrier family 6 (neurotransmitter transporter, GABA), member 1 (SLC6A1) antibody
  • solute carrier family 6 (neurotransmitter transporter, GABA), member 1, like (slc6a1l) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 1 (Slc6a1) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 1 (SLC6A1) antibody
  • A730043E01 antibody
  • GABATHG antibody
  • GABATR antibody
  • Gabt antibody
  • Gabt1 antibody
  • GAT-1 antibody
  • GAT1 antibody
  • si:ch211-280e18.1 antibody
  • si:dkey-164m14.1 antibody
  • slc6a1 antibody
  • XT-1 antibody
  • Xtrp1 antibody

Protein level used designations for SLC6A1

gamma-aminobutyric acid (GABA-A) transporter 1 , sodium- and chloride-dependent GABA transporter 1 , solute carrier family 6 member 1 , GABA transporter GAT-1 homolog , GABA transporter protein , GAT-1 , solute carrier family 6 (neurotransmitter transporter, GABA), member 1 , GABA transporter 1

GENE ID SPECIES
734186 Xenopus laevis
232333 Mus musculus
415960 Gallus gallus
484655 Canis lupus familiaris
407118 Bos taurus
568985 Danio rerio
79212 Rattus norvegicus
6529 Homo sapiens
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