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anti-Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) Antibodies

SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. Additionally we are shipping SLC6A5 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC6A5 104245  
SLC6A5 9152 Q9Y345
SLC6A5 171148 P58295
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Top anti-SLC6A5 Antibodies at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC6A5 Antibody Titration: 0.2-1 ug/mlPositive Control: PANC1 cell lysate WB Suggested Anti-SLC6A5  Antibody Titration: 0.2-1 µg/mL  Positive Control: PANC1 cell lysate  SLC6A5 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μL Log in to see 8 to 10 Days
$566.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB SLC6A5 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Rat Rabbit Un-conjugated IP, IHC, WB 50 μg Log in to see 5 to 6 Days
$398.48
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Rat Rabbit Un-conjugated ELISA, WB   50 μg Log in to see 11 to 16 Days
$419.57
Details

SLC6A5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human
,
,
Rat (Rattus)


More Antibodies against SLC6A5 Interaction Partners

Mouse (Murine) Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) interaction partners

  1. that the deletion of VIAAT (show SLC32A1 Antibodies) in GlyT2-Cre expressing neurons also strongly affects GABAergic transmission

  2. Results suggest that the excessive GAT-1 (show SLC6A1 Antibodies) and GlyT-1 (show GLYT1 Antibodies)/2 heterotransporter-mediated Glu (show GCG Antibodies) release, in the spinal cord of SOD1 (show SOD1 Antibodies)(G93A) mice, is due to the heterotransporter over-expression at the nerve terminal membrane, promoted by the excessive Glu (show GCG Antibodies) exocytosis

  3. Report that in the presence of a GlyT2 mechanism-based toxicity, reversible inhibitors might allow a tolerable balance between efficacy and toxicity.

  4. These alterations in the activities and expression profiles of the GlyTs suggest that the contributions of GlyT1 (show GLYT1 Antibodies) and GlyT2 to the regulation of extracellular glycine concentrations at glycinergic synapses changes during development.

  5. Data show that the GlyT2 protein is undetectable in homozygous mutants, indicating a null allele.

  6. In the first postnatal week, loss of the glycine transporter 2 is neither compensated by glycine de-novo synthesis nor by up-regulation of the GABAergic transmission in GlyT2(-/-) mice.

  7. These data indicate that the C-terminal PDZ (show INADL Antibodies)-ligand motif of GlyT2 plays an important role in transporter trafficking to and/or stabilization at synaptic sites.

  8. Glyt2-mediated release of glycine from axon terminals involves exocytosis triggered by intraterminal mitochondrial Ca2 (show CA2 Antibodies)+ ions.

  9. our results demonstrate the central role played by GlyT2 in determining inhibitory phenotype and therefore in the physiology and pathology of inhibitory circuits.

Human Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) interaction partners

  1. analysis of the human SLC6A5 (show SLC6A2 Antibodies) gene mutation associated with hyperekplexia

  2. Report that in the presence of a GlyT2 mechanism-based toxicity, reversible inhibitors might allow a tolerable balance between efficacy and toxicity.

  3. Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster.

  4. A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2.

  5. This study firmly establishes the combination of missense, nonsense, frameshift, and splice site mutations in the GlyT2 gene as the second major cause of startle disease.

  6. A transgenic cell line is studied in which green fluorescent protein (GFP) is expressed under the control of the promoter for the glycine transporter GlyT2 during zebrafish development.

  7. Inspiratory-modulated neurons with pacemaker properties are present in the preBotzinger complex of newborn transgenic mice and express the glycine tranporter (GlyT)2 protein.

  8. SLC6A5 (show SLC6A2 Antibodies) mutations result in defective subcellular GlyT2 localization, decreased glycine uptake or both, with selected mutations affecting predicted glycine and Na+ binding sites.

  9. results are consistent with GLYT2 being a disease gene in human hyperekplexia

  10. SLC6A5 (show SLC6A2 Antibodies) gene is associated with schizophrenia.

SLC6A5 Antigen Profile

Protein Summary

This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia\; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.

Gene names and symbols associated with SLC6A5

  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (SLC6A5) antibody
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (LOC100339626) antibody
  • solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Slc6a5) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 5 (SLC6A5) antibody
  • solute carrier family 6 (neurotransmitter transporter), member 5 (Slc6a5) antibody
  • GLYT-2 antibody
  • GLYT2 antibody
  • HKPX3 antibody
  • NET1 antibody
  • prestin antibody
  • SLC6A5 antibody

Protein level used designations for SLC6A5

solute carrier family 6 (neurotransmitter transporter, glycine), member 5 , sodium- and chloride-dependent glycine transporter 2-like , glyT-2 , glycine transporter 2 , sodium- and chloride-dependent glycine transporter 2 , solute carrier family 6 member 5

GENE ID SPECIES
422974 Gallus gallus
466470 Pan troglodytes
612095 Canis lupus familiaris
704703 Macaca mulatta
100339626 Oryctolagus cuniculus
100431924 Pongo abelii
100585180 Nomascus leucogenys
104245 Mus musculus
9152 Homo sapiens
171148 Rattus norvegicus
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