You are viewing an incomplete version of our website. Please click to reload the website as full version.

Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 19 Proteins (SLC6A19)

SLC6A19 encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Additionally we are shipping SLC6A19 Antibodies (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC6A19 74338 Q9D687
SLC6A19 340024 Q695T7
Rat SLC6A19 SLC6A19 664630 Q2A865
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SLC6A19 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SLC6A19 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 19 (SLC6A19) Interaction Partners

Mouse (Murine) Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 19 (SLC6A19) interaction partners

  1. analysis of the interaction of amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin (show TMEM27 Proteins)

  2. Slc6a19 expression in the intestine is regulated at three different levels involving promoter methylation, histone modification, and opposing transcription factors.

  3. the presence of digestive protein complexes in the intestinal brush-border containing the peptidases APN (show ANPEP Proteins) and ACE2 (show ACE2 Proteins) and the neutral amino acid transporter B0AT1

  4. Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse.

  5. Average loss of solute carrier (show SERTAD2 Proteins) expression was similar in acute tubular necrosis (77%) and T cell-mediated rejection (75%) with high correlation of individual transcripts.

  6. Glucocorticoid inducible kinase isoforms SGK1 (show SGK1 Proteins)-3 are novel potent stimulators of Slc6a19 and may thus participate in the regulation of neutral amino acid transport in vivo.

  7. We isolated the human homolog of B(0)AT1, called SLC6A19, and determined its size and molecular organization. We then identified mutations in SLC6A19 in members of the original family in whom Hartnup disorder was discovered

  8. The mechanism of the mouse (m)B0AT1 (slc6a19) transporter was studied in detail using two electrode voltage-clamp techniques and tracer studies in the Xenopus oocyte expression system.

  9. The relatively constant [Na(+)] along the renal proximal tubule both drives the uptake of neutral amino acids via B(0)AT1 thermodynamically and ensures that, upon binding, these are translocated efficiently into the cell.

  10. This study shows the luminal brush-border localization of the Na(+)-dependent amino and imino acid transporters B degrees AT1 (show SLC33A1 Proteins) and XT3s1/SIT1 (show SIT1 Proteins) in kidney and intestine.

Human Solute Carrier Family 6 (Neutral Amino Acid Transporter), Member 19 (SLC6A19) interaction partners

  1. SIT1 (show SIT1 Proteins), B(0)AT1 and ACE2 (show ACE2 Proteins) were co-localized in the brush-border membrane of small intestine enterocytes.

  2. PKB/Akt (show AKT1 Proteins) up-regulates SLC6A19 activity, which may foster amino acid uptake into PKB/Akt (show AKT1 Proteins)-expressing epithelial and tumor cells.

  3. JAK2 (show JAK2 Proteins) up-regulates SLC6A19 activity which may foster amino acid uptake into JAK2 (show JAK2 Proteins) expressing cells.

  4. Average loss of solute carrier (show SERTAD2 Proteins) expression was similar in acute tubular necrosis (77%) and T cell-mediated rejection (75%) with high correlation of individual transcripts.

  5. A novel SLC6A19 gene mutation is associated with late-onset seizures in a Korean patient with Hartnup disorder.

  6. We identified six mutations in SLC6A19 that cosegregated with disease in the predicted recessive manner, with most affected individuals being compound heterozygotes.

  7. Hartnup disorder is allelically heterogeneous with two mutated SLC6A19 allele.

  8. These findings suggest that the rare SLC6A19-MS7 allele may be a risk factor for hypertension.

  9. Suggest that amino acid transporters B(0)AT1 and b(0,+)AT are involved in the reabsorption of L-citrulline in the kidney, at least in part, by mediating the apical membrane transport of L-citrulline in renal tubule cells.

  10. novel homozygous mutation of G284R in the transmembrane domain of the SLC6A19 transporter found in the proband, with typical dermatologic and neurologic manifestations and increased levels of urinary neutral amino acids

SLC6A19 Protein Profile

Protein Summary

This gene encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Mutations in this gene result in Hartnup disorder.

Gene names and symbols associated with SLC6A19

  • solute carrier family 6 (neurotransmitter transporter), member 19 (Slc6a19)
  • solute carrier family 6 (neutral amino acid transporter), member 19 (SLC6A19)
  • solute carrier family 6 (neutral amino acid transporter), member 19 (Slc6a19)
  • 4632401C08Rik protein
  • B0at1 protein
  • B<0>AT1 protein
  • HND protein

Protein level used designations for SLC6A19

b(0)AT1 , sodium-dependent neutral amino acid transporter B(0)AT1 , solute carrier family 6 member 19 , system B(0) neutral amino acid transporter AT1 , sodium-dependent amino acid transporter system B0 , solute carrier family 6 (neurotransmitter transporter), member 19 , system B0 neutral amino acid transporter , neutral amino acid transporter , solute carrier family 6, member 19 , system B0 neutral amino acid transporter SLC6A19 , sodium-dependent neutral amino acid transporter B(0)

GENE ID SPECIES
74338 Mus musculus
340024 Homo sapiens
664630 Rattus norvegicus
100683912 Canis lupus familiaris
641346 Sus scrofa
100173524 Pongo abelii
Selected quality suppliers for SLC6A19 Proteins (SLC6A19)
Did you look for something else?