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Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. Additionally we are shipping SLC6A11 Antibodies (48) and SLC6A11 Proteins (4) and many more products for this protein.
Development of GABA-removal system and its relationship to development of GABAergic networks studied by examination of changes in GAT-1 and GAT-3 expression and localization in embryonic and postnatal mouse spinal cord
When transfected into Xenopus, zinc is a potent inhibitor of GAT4 in the hippocampus.
3p25.3 microdeletion of GABA transporters SLC6A1 and SLC6A11 results in intellectual disability, epilepsy and stereotypic behavior.
Binding assays employing membrane preparations obtained from a stably GAT3 expressing HEK293 cell line and DDPM-1007 as nonlabeled GAT3 marker were performed. In these experiments specific binding of DDPM-1007 at GAT3 could be unambiguously detected.
The results suggest that GAT3 c.1572T may be one of the contributing factors with a modest effect on antiepileptic drug (AEDs) pharmacoresistance in the epileptic brain.
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994
, gamma-aminobutyric acid (GABA-A) transporter 4
, sodium- and chloride-dependent GABA transporter 3
, sodium- and chloride-dependent GABA transporter 4
, solute carrier family 6 member 11
, GABA transporter GAT-3
, solute carrier family 6 (neurotransmitter transporter, GABA), member 11
, GABA transporter 3