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Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) ELISA Kits

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Additionally we are shipping SLC7A8 Antibodies (34) and SLC7A8 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SLC7A8 SLC7A8 23428 Q9UHI5
Anti-Rat SLC7A8 SLC7A8 84551 Q9WVR6
Anti-Mouse SLC7A8 SLC7A8 50934 Q9QXW9
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More ELISA Kits for SLC7A8 Interaction Partners

Pig (Porcine) Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

  1. molecular cloning of LAT2 (show LAT2 ELISA Kits)

Human Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

  1. LAT1 (show LAT ELISA Kits) and LAT2 (show LAT2 ELISA Kits) are present and functional in the syncytiotrophoblast MVM, whereas LAT2 (show LAT2 ELISA Kits) is also expressed in the BM and in the fetal capillary endothelium.

  2. Compared with the adult cerebral cortex, mRNAs encoding OATP1A2 (show SLCO1A2 ELISA Kits), OATP1C1 (show SLCO1C1 ELISA Kits), OATP3A1 (show SLCO3A1 ELISA Kits) variant 2, OATP4A1 (show OATP-E ELISA Kits), LAT2 (show LAT2 ELISA Kits) and CD98 (show SLC3A2 ELISA Kits) were reduced in fetal cortex at different gestational ages, whilst mRNAs encoding MCT8 (show MCT8 ELISA Kits), MCT10 (show SLC16A10 ELISA Kits), OATP3A1 (show SLCO3A1 ELISA Kits) variant 1 and LAT1 (show LAT ELISA Kits) were similar.

  3. the interaction of CD98 (show SLC3A2 ELISA Kits)/LAT2 (show LAT2 ELISA Kits) with ICAM-1 (show ICAM1 ELISA Kits), found to be expressed to the basolateral domain, and the potential of such interaction on intracellular signal activation in Caco2-BBE (show ENO3 ELISA Kits) cell monolayers

  4. identify LAT1 (show LAT ELISA Kits) and LAT2 (show LAT2 ELISA Kits) as members of system L that mediate transmembrane movement of l-CSNO

  5. Genetic variation in LAT1 (show LAT ELISA Kits) and LAT2 (show LAT2 ELISA Kits) does not appear to be a major cause of inter-individual variability in pharmacokinetics and of adverse reactions to melphalan.

Mouse (Murine) Solute Carrier Family 7 (Amino Acid Transporter, L-Type), Member 8 (SLC7A8) interaction partners

  1. Circulating thyroid hormones, thyrotropin and thyroid hormone-responsive (show THRSP ELISA Kits) genes remained unchanged in Slc7a8(-/-) mice, possibly because of functional compensation by the thyroid hormone (show PTH ELISA Kits) transporter Mct8 (show MCT8 ELISA Kits), which is co-expressed in many cell types

  2. the aromatic amino acid diffusion pathway TAT1 (show SLC16A10 ELISA Kits) can control neutral amino acid efflux via neighboring exchanger LAT2-4F2hc (show SLC3A2 ELISA Kits), by recycling its aromatic influx substrates

  3. The positive effect of non-T cell activation linker (NTAL (show LAT2 ELISA Kits)) on Akt (show AKT1 ELISA Kits) phosphorylation and mast cell survival requires LAT (show LAT ELISA Kits).

  4. LAT1 (show SLC7A5 ELISA Kits), and LAT2 mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 (show Slco1a1 ELISA Kits) and NTCP (show SLC10A1 ELISA Kits) mRNAs were not.

SLC7A8 Antigen Profile

Antigen Summary

Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Plays an essential role in the reabsorption of neutral amino acids from the epithelial cells to the bloodstream in the kidney (By similarity).

Gene names and symbols associated with SLC7A8

  • solute carrier family 7 (amino acid transporter light chain, L system), member 8 (slc7a8) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 8 (SLC7A8) antibody
  • solute carrier family 7 (amino acid transporter, L-type), member 8 (SLC7A8) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 8 (Slc7a8) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (slc7a8) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Slc7a8) antibody
  • 4F2LC-5 antibody
  • AA408822 antibody
  • Lat2 antibody
  • Lat4 antibody
  • LPI-PC1 antibody
  • si:ch211-14a17.3 antibody
  • si:zc14a17.3 antibody
  • XAA2 antibody

Protein level used designations for SLC7A8

solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 , solute carrier family 7 (amino acid transporter, L-type), member 8 , large neutral amino acids transporter small subunit 2 , L-type amino acid transporter 2 , solute carrier family 7 member 8 , integral membrane protein E16H , glycoprotein-associated amino acid transporter LAT2 , 4F2-LC5 , cationic amino acid transporter y+ system , mLAT2 , solute carrier family 8 (cationic amino acid transporter, y+ system), member 7

GENE ID SPECIES
394580 Xenopus (Silurana) tropicalis
452793 Pan troglodytes
713511 Macaca mulatta
100134829 Sus scrofa
100172820 Pongo abelii
380297 Xenopus laevis
23428 Homo sapiens
490608 Canis lupus familiaris
536818 Bos taurus
100009408 Oryctolagus cuniculus
84551 Rattus norvegicus
368665 Danio rerio
50934 Mus musculus
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