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Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 Proteins (Slc7a7)

The protein encoded by Slc7a7 is the light subunit of a cationic amino acid transporter. Additionally we are shipping Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 Kits (27) and Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 Antibodies (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Slc7a7 9056 Q9UM01
Rat Slc7a7 Slc7a7 83509 Q9R0S5
Mouse Slc7a7 Slc7a7 20540 Q9Z1K8
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Top Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 Proteins at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

Slc7a7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

More Proteins for Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) Interaction Partners

Human Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) interaction partners

  1. heteromerization of y+LAT1 and 4F2hc (show SLC3A2 Proteins) within the cell is not disrupted by any of the tested LPI mutations

  2. SLC7A7 genetic variants are associated with increase risk for glioma in a Chinese population.

  3. SLC7A7 plays a critical role in glioblastoma carcinogenesis and overexpression of SLC7A7 is correlated with worse outcomes in patients

  4. SLC7A7/y+LAT1 mutations lead to a defective phenotype of macrophages resulting in lysinuric Protein Intolerance.

  5. during differentiation of human monocytes from peripheral blood, SLC7A7 mRNA and system y(+)L activity are increased

  6. novel SLC7A7 mutations in patients with lysinuric protein intolerance

  7. expression levels and putative 5' promoter elements of the SLC7A7 gene

  8. putative multiheteromeric structure of both [4F2hc/y(+)LAT-1] and [4F2hc/y(+)LAT-2], and the interference between y(+)LAT-1 and y(+)LAT-2 proteins may have a role in the pathogenesis of lysinuric protein intolerance

  9. mutations of the SLC7A7 gene may have a role in lysinuric protein intolerance

  10. identified a novel alternative, TATA-box-containing promoter that plays a role in the tissue-specific regulation of SLC7A7 gene expression

Mouse (Murine) Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) interaction partners

  1. The expression of Mct8 and L-type amino acid transporters Lat2 and Lat1 are determined in brain neurons during development.

  2. Increased LAT1 expression can be induced by lipid oxidation products relevant to inflammatory responses in atherogenesis. LAT1 mediates lysophosphatidylcholine-enhanced cytokine production by endothelial cells.

  3. selective regulation of SNAT3 (show SLC38A3 Proteins) and y(+)LAT1 expression may serve a major role in the renal adaptation to acid secretion and thus for systemic acid-base balance.

  4. The Slc7a7(-/-) mouse displayed intrauterine growth restriction, leading to neonatal lethality. After heavy protein ingestion, the surviving adult animals presented metabolic derangement consistent with lysinuric protein intolerance.

  5. LAT1, and LAT2 (show SLC7A8 Proteins) mRNAs were detected in fetal and postnatal femurs and in MC3T3-E1 cells, while OATP1 and NTCP (show SLC10A1 Proteins) mRNAs were not.

Solute Carrier Family 7 (Amino Acid Transporter Light Chain, Y+L System), Member 7 (Slc7a7) Protein Profile

Protein Summary

The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with Slc7a7

  • solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 (SLC7A7)
  • solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 (Slc7a7)
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 (Slc7a7)
  • AI790233 protein
  • LAT3 protein
  • LPI protein
  • MOP-2 protein
  • my+lat1 protein
  • y+LAT-1 protein
  • y+LAT1 protein

Protein level used designations for Slc7a7

Y+L amino acid transporter 1 , monocyte amino acid permease 2 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 , y(+)L-type amino acid transporter 1 , solute carrier family 7 member 7 , y+LAT-1 , y+LAT1

GENE ID SPECIES
9056 Homo sapiens
83509 Rattus norvegicus
20540 Mus musculus
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