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anti-Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) Antibodies

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Additionally we are shipping SLC7A5 Kits (3) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC7A5 8140 Q01650
SLC7A5 50719 Q63016
SLC7A5 20539 Q9Z127
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Top anti-SLC7A5 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185255 (0.01µg/ml) staining of peripheral blood mononucleocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB Host: Rabbit  Target Name: SLC7A5  Sample Tissue: Human HepG2  Antibody Dilution: 1.0 µg/mL SLC7A5 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC (p) Anti-SLC7A5 antibody  ABIN1049351 IHC staining of human placenta, terminal villi. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse brain lysates probed with Rabbit Anti-SLC7A5 Polyclonal Antibody (ABIN1387470) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted and observed band size: 55kDa Formalin-fixed and paraffin embedded rat brain labeled with Anti-SLC7A5 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) Human Placenta (formalin-fixed, paraffin-embedded) stained with SLC7A5 antibody ABIN213435 at 20 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Dog Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Gibbon Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Dog Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

SLC7A5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SLC7A5 Antibodies

  1. Human Polyclonal SLC7A5 Primary Antibody for ELISA, WB - ABIN185255 : Finco, Kadlecek, Zhang, Samelson, Weiss: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. in Immunity 1998 (PubMed)

More Antibodies against SLC7A5 Interaction Partners

Human Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

  1. Proliferation of breast cancer cells is dependent on the expression of both LAT1 (show LAT Antibodies) and AHR (show AHR Antibodies).

  2. CD98 (show SLC3A2 Antibodies) promotes cell spreading and tumorigenicity by triggering integrin clustering and enhancing cell adhesion to the extracellular matrix.

  3. Propose regulation of placental SNAT2 (show SLC38A2 Antibodies)/LAT1 (show LAT Antibodies) ubiquitination by mTORC1 and Nedd4-2 (show NEDD4L Antibodies).

  4. Independently of Gleason score, aberrant overexpression of LAT1 (show LAT Antibodies) in prostatic adenocarcinoma could predict LP under EM. Although prostate biopsy samples are small, LAT1 (show LAT Antibodies) may be a novel prognostic biomarker of LP.

  5. LAT1 (show LAT Antibodies) is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter (show SLC43A2 Antibodies).

  6. LAT1 (show LAT Antibodies) can serve as a significant prognostic factor to predict a poor outcome and it may therefore play an important role in the aggressiveness of cutaneous melanoma.

  7. exposure to diesel exhaust particle extract induces functional overexpression of the amino acid transporter (show SLC43A2 Antibodies) LAT1 (show LAT Antibodies)/CD98hc (show SLC3A2 Antibodies) in lung cells

  8. LAPTM4b recruits LAT1 (show LAT Antibodies)-4F2hc (show SLC3A2 Antibodies) to lysosomes, leading to uptake of leucine into lysosomes.

  9. These results suggest that LAT1 (show LAT Antibodies) expression is associated with disease progression in gastric carcinoma.

  10. LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) are present and functional in the syncytiotrophoblast MVM, whereas LAT2 (show LAT2 Antibodies) is also expressed in the BM and in the fetal capillary endothelium.

Cow (Bovine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

Mouse (Murine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

  1. Results demonstrate that lipopolysaccharide-induced inflammation decreases LAT1 mRNA expression at the blood-brain barrier in a very similar manner to primary thyroid hormone (show PTH Antibodies) transporters, while changes in LAT1 protein level follow a slower kinetics.

  2. HIF-2alpha (show EPAS1 Antibodies)/mTORC1/SLC7A5 pathway mediates proliferation and tumor promoting properties of HIF-2alpha (show EPAS1 Antibodies).

  3. expression of candidate thyroid hormone (show PTH Antibodies) transporters Lat1, Mct8 (show MCT8 Antibodies), Mct10 (show SLC16A10 Antibodies), and Oatp1c1 (show SLCO1C1 Antibodies) in mouse cochlear development

  4. These results demonstrate that LAT-1 plays an important role in trophoblast invasion.

  5. TA1 therefore appears to play a modulatory role in catecholaminergic function

  6. Expression studies of LAT-1 in developing mouse placenta show highest levels of LAT-1 mRNA in trophoblast giant cells at the time of implantation, followed by maternal decidua, ectoplacental cone and epiblast.

SLC7A5 Antigen Profile

Protein Summary

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L- leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

Gene names and symbols associated with SLC7A5

  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (SLC7A5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (slc7a5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (LOC100218991) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 5 (SLC7A5) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 5 (Slc7a5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (Slc7a5) antibody
  • 4F2LC antibody
  • CD98 antibody
  • D0H16S474E antibody
  • D16S469E antibody
  • E16 antibody
  • hLAT1 antibody
  • JHI-21 antibody
  • LAT-1 antibody
  • LAT1 antibody
  • MPE16 antibody
  • SLC7A5 antibody
  • slc7a5a antibody
  • TA1 antibody

Protein level used designations for SLC7A5

solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 , L amino acid transporter-1 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 a , large neutral amino acids transporter small subunit 1-like , L-type amino acid transporter 1 , 4F2 LC , 4F2 light chain , CD98 light chain , integral membrane protein E16 , large neutral amino acids transporter 1 , large neutral amino acids transporter small subunit 1 , sodium-independent neutral amino acid transporter LAT1 , solute carrier family 7 member 5 , y+ system cationic amino acid transporter , 4F2LC , tumor-associated protein 1 , LAT1 light chain , blood-brain barrier large neutral amino acid transporter light chain

GENE ID SPECIES
454300 Pan troglodytes
734908 Xenopus laevis
100070633 Equus caballus
100448375 Pongo abelii
100468553 Ailuropoda melanoleuca
100134831 Sus scrofa
100218991 Taeniopygia guttata
8140 Homo sapiens
50719 Rattus norvegicus
100008844 Oryctolagus cuniculus
415832 Gallus gallus
489667 Canis lupus familiaris
282369 Bos taurus
20539 Mus musculus
Selected quality suppliers for anti-SLC7A5 (SLC7A5) Antibodies
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