anti-Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) Antibodies

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Additionally we are shipping SLC7A5 Kits (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC7A5 8140 Q01650
SLC7A5 50719 Q63016
SLC7A5 20539 Q9Z127
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Top anti-SLC7A5 Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185255 (0.01µg/ml) staining of peripheral blood mononucleocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse brain lysates probed with Rabbit Anti-SLC7A5 Polyclonal Antibody (ABIN1387470) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted and observed band size: 55kDa Formalin-fixed and paraffin embedded rat brain labeled with Anti-SLC7A5 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), IHC Left: primary breast cancer tumorRight: normal breast tissue 0.125 mg Log in to see 7 to 9 Days
$538.13
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Goat Un-conjugated ELISA, WB Western Blot: SLC7A5 Antibody [NBP1-51935] (0.3ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Dog Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$515.63
Details
Gibbon Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 12 to 14 Days
$541.80
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 12 to 14 Days
$541.80
Details

SLC7A5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SLC7A5 Antibodies

  1. Human Polyclonal SLC7A5 Primary Antibody for IF (p), IHC (p) - ABIN1387470 : Beals, Sukiennik, Nallabelli, Emmons, van Vliet, Young, Ulanov, Li, Paluska, De Lisio, Burd: Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults. in The American journal of clinical nutrition 2016 (PubMed)
    Show all 2 references for 1387470

  2. Human Polyclonal SLC7A5 Primary Antibody for ELISA, WB - ABIN4354499 : Ohno, Suda, Masuko, Yagi, Hashimoto, Masuko: Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human L-type amino-acid transporter 1. in Cancer science 2008 (PubMed)

  3. Human Polyclonal SLC7A5 Primary Antibody for ELISA, WB - ABIN185255 : Finco, Kadlecek, Zhang, Samelson, Weiss: LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. in Immunity 1998 (PubMed)

  4. Human Polyclonal SLC7A5 Primary Antibody for IHC (p), IHC - ABIN152153 : Padbury, Diah, McGonnigal, Miller, Fugere, Kuzniar, Thompson: Transcriptional regulation of the LAT-1/CD98 light chain. in Biochemical and biophysical research communications 2004 (PubMed)

More Antibodies against SLC7A5 Interaction Partners

Human Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

  1. MTA1 (show MTA1 Antibodies) expression was positively correlated with LAT1 (show LAT Antibodies) (p=0.013) and CD34 (show CD34 Antibodies) (p=0.034) expression, but not with Ki-67 (show MKI67 Antibodies) (p=0.078). MTA1 (show MTA1 Antibodies) shows promise as a diagnostic and prognostic marker in esophageal cancer, and we anticipate that the gene will also prove to be a good therapeutic target.

  2. LAT1 (show LAT Antibodies) overexpression was common in Brain Metastases and was specific for Brain Metastases as compared to healthy brain. These results could explain the specific Brain Metastases uptake on PET-AA.

  3. LAT1 (show LAT Antibodies) and LAT2 (show LAT2 Antibodies) were overexpressed in both pheochromocytoma and medullary thyroid carcinoma by comparison with normal tissues.

  4. he findings in this study indicate a regulation relationship between CRKL (show CRKL Antibodies) and SLC7A5, and provide useful evidence for gastric cancer therapeutic strategies.

  5. Study shows that the solute carrier (show SERTAD2 Antibodies) transporter 7a5 (show MACC1 Antibodies) (SLC7A5), a large neutral amino acid transporter (show SLC6A19 Antibodies) localized at the blood brain barrier (BBB (show ALMS1 Antibodies)), has an essential role in maintaining normal levels of brain branched-chain amino acids; also identified several patients with autistic traits and motor delay carrying deleterious homozygous mutations in the SLC7A5 gene.

  6. The LAT1 (show LAT Antibodies) isoform was confirmed as the major tyrosine transporter in patients with schizophrenia. However, the kinetic parameters (maximal transport capacity, affinity of the binding sites, and diffusion constant of tyrosine transport through the LAT1 (show LAT Antibodies) isoform) did not differ between patients with schizophrenia and controls.

  7. Expression levels of CD98 (show SLC3A2 Antibodies) and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) tissues relative to those of normal liver tissues.

  8. Authors demonstrate that LAT1 (show LAT Antibodies) is a critical transporter for human thymic carcinoma cells. LAT1 (show LAT Antibodies) was strongly expressed in human thymic carcinoma tissues.

  9. Our study demonstrates that suppression of l-type amino acid transporter-1 activity using JPH203 might be used as a new therapeutic strategy for cholangiocarcinoma treatment.

  10. This study shows the utility of (18)F-FBPA as a tumor-specific probe of LAT1 (show LAT Antibodies) with low accumulation in the inflammatory lesions.

Cow (Bovine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

Mouse (Murine) Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5) interaction partners

  1. results revealed that L-type amino acid transporter 1 solute carrier family 7 member 5(lat1) might play an important role in the decidual progression both in vitro and in vivo in the mouse

  2. Results demonstrate that lipopolysaccharide-induced inflammation decreases LAT1 mRNA expression at the blood-brain barrier in a very similar manner to primary thyroid hormone (show PTH Antibodies) transporters, while changes in LAT1 protein level follow a slower kinetics.

  3. HIF-2alpha (show EPAS1 Antibodies)/mTORC1/SLC7A5 pathway mediates proliferation and tumor promoting properties of HIF-2alpha (show EPAS1 Antibodies).

  4. expression of candidate thyroid hormone (show PTH Antibodies) transporters Lat1, Mct8 (show MCT8 Antibodies), Mct10 (show SLC16A10 Antibodies), and Oatp1c1 (show SLCO1C1 Antibodies) in mouse cochlear development

  5. These results demonstrate that LAT-1 plays an important role in trophoblast invasion.

  6. TA1 therefore appears to play a modulatory role in catecholaminergic function

  7. Expression studies of LAT-1 in developing mouse placenta show highest levels of LAT-1 mRNA in trophoblast giant cells at the time of implantation, followed by maternal decidua, ectoplacental cone and epiblast.

SLC7A5 Antigen Profile

Protein Summary

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L- nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L- leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.

Gene names and symbols associated with SLC7A5

  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (SLC7A5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (slc7a5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (LOC100218991) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 5 (SLC7A5) antibody
  • solute carrier family 7 (amino acid transporter light chain, L system), member 5 (Slc7a5) antibody
  • solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (Slc7a5) antibody
  • 4F2LC antibody
  • CD98 antibody
  • D0H16S474E antibody
  • D16S469E antibody
  • E16 antibody
  • hLAT1 antibody
  • JHI-21 antibody
  • LAT-1 antibody
  • LAT1 antibody
  • MPE16 antibody
  • SLC7A5 antibody
  • slc7a5a antibody
  • TA1 antibody

Protein level used designations for SLC7A5

solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 , L amino acid transporter-1 , solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 a , large neutral amino acids transporter small subunit 1-like , L-type amino acid transporter 1 , 4F2 LC , 4F2 light chain , CD98 light chain , integral membrane protein E16 , large neutral amino acids transporter 1 , large neutral amino acids transporter small subunit 1 , sodium-independent neutral amino acid transporter LAT1 , solute carrier family 7 member 5 , y+ system cationic amino acid transporter , 4F2LC , tumor-associated protein 1 , LAT1 light chain , blood-brain barrier large neutral amino acid transporter light chain

GENE ID SPECIES
454300 Pan troglodytes
734908 Xenopus laevis
100070633 Equus caballus
100448375 Pongo abelii
100468553 Ailuropoda melanoleuca
100134831 Sus scrofa
100218991 Taeniopygia guttata
8140 Homo sapiens
50719 Rattus norvegicus
100008844 Oryctolagus cuniculus
415832 Gallus gallus
489667 Canis lupus familiaris
282369 Bos taurus
20539 Mus musculus
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