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SLC7A10, in association with 4F2HC (SLC3A2\; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008].. Additionally we are shipping SLC7A10 Kits (4) and SLC7A10 Proteins (4) and many more products for this protein.
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Mouse (Murine) Polyclonal SLC7A10 Primary Antibody for IHC (fro), WB - ABIN548990
Fukasawa, Segawa, Kim, Chairoungdua, Kim, Matsuo, Cha, Endou, Kanai et al.: Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino ... in The Journal of biological chemistry 2000
Show all 2 Pubmed References
Asc-1 has a novel role in regulating NMDA receptor-dependent synaptic activity by mediating concurrent non-vesicular release of D-serine and glycine.
The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission
The amino acid transporter ASC-1 is a white adipocyte-specific cell surface protein (show CD28 Antibodies).
The results presented reveal that Asc-1 is the only high affinity D-serine transporter in the mouse CNS and is the predominant mechanism for D-serine reuptake.
data support ASCT2 (show SLC1A5 Antibodies) function in both neuron and astrocyte cultures and identify a discrepancy between observed asc-1 immunoreactivity and lack of functional asc-1 activity in neuron cultures, elucidating processes that govern D-serine regulation
The amino acid transporter (show SLC43A2 Antibodies) ASC-1 (show RPL3 Antibodies) is a white adipocyte-specific cell surface protein (show CD28 Antibodies).
ASC1 (show RPL3 Antibodies) is a target for ufmylation and that UFBP1 is an essential component for ASC1 (show RPL3 Antibodies) ufmylation.
In conclusion, SLC7A10 had no apparent degree of association with schizophrenia as a candidate susceptibility gene in the disease per se.
The lack of expression of asc-1 (show RPL3 Antibodies) in the proximal tubule indicates that it plays no role in the bulk of renal reabsorption of amino acids
SLC7A10, in association with 4F2HC (SLC3A2\; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000
, asc-type amino acid transporter 1
, solute carrier family 7 member 10
, D- and L-serine transporter Asc-1
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 10
, solute carrier family 7, (neutral amino acid transporter, y+ system) member 10
, solute carrier family 7, (cationic amino acid transporter, y+ system) member 10