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Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Proteins (SLC8A3)

SLC8A3 encodes a member of the sodium/calcium exchanger integral membrane protein family. Additionally we are shipping Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Antibodies (53) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC8A3 6547 P57103
Rat SLC8A3 SLC8A3 140448 P70549
SLC8A3 110893  
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Top Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SLC8A3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Interaction Partners

Human Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) interaction partners

  1. Ayloid beta mediates calpain cleavage of NCX3 in Alzheimer's disease brain.

  2. NCX1 (show SLC8A1 Proteins) and NCX3 -represent two promising druggable targets for setting on new strategies in stroke therapy.

  3. NCX (show TLX2 Proteins) isoforms (NCX2, NCX3) contribute to mitochondrial Na(+)/Ca(2 (show CA2 Proteins)+) exchange in human DAergic neurons and may act downstream of PINK1 (show PINK1 Proteins) in the prevention of neurodegeneration by m[Ca(2 (show CA2 Proteins)+)] accumulation.

  4. the large cytosolic loop of NCX1 (show SLC8A1 Proteins), NCX2, and NCX3 is involved in acquisition of immunosuppressive drug specificity

  5. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte.

  6. human macrophages and monocytes express NCX1 (show SLC8A1 Proteins) and NCX3 that operate in a bidirectional manner to restore [Ca(2 (show CA2 Proteins)+)](i) to generate Ca(2 (show CA2 Proteins)+) signals and to induce TNF-alpha (show TNF Proteins) production.

  7. calcium signaling mediated by NCX3 has a crucial role in oligodendrocyte maturation and myelin formation.

  8. Human platelets express K(+) -independent Na(+) /Ca(2 (show CA2 Proteins)+) exchangers NCX1.3, NCX3.2 and NCX3.4.

  9. Data suggest that NCX (show TLX2 Proteins)-mediated Ca(2 (show CA2 Proteins)+) fluxes normally exist in human ASM (show SMPD1 Proteins) (potentially contributing to rapid Ca(2 (show CA2 Proteins)+) fluxes), and contribute to enhanced [Ca(2 (show CA2 Proteins)+)](i) regulation in airway inflammation.

  10. Results demonstrate a selective regulation of NCX1 (show SLC8A1 Proteins), NCX2 and NCX3 isoforms in Alzheimer's disease cortex, specifically in terminals containing amyloid-beta.

Mouse (Murine) Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) interaction partners

  1. Demonstrate that NCX3 genetic deletion protects against ziram-induced neurotoxicity and suggest NCX3 and its downstream molecular pathways as key factors involved in ziram toxicity.

  2. NCX3 regulates mitochondrial calcium handling from the outer mitochondrial membrane through an AKAP121 (show AKAP1 Proteins)-anchored signaling complex.

  3. Function and regulation of the Na+-Ca2+ exchanger (show SLC8A1 Proteins) NCX3 splice variants in brain and skeletal muscle.

  4. the use of genetic-modified mice for NCX1 (show SLC8A1 Proteins), NCX2, and NCX3 represents a fruitful strategy to characterize the physiological role exerted by NCX (show SLC8A1 Proteins) in CNS

  5. Functional studies, as well as mRNA and protein expression analyses, revealed that NCX1 and NCX3, but not NCX2, were divergently modulated during OPC differentiation into oligodendrocyte.

  6. the solution structure of NCX3 calcium binding domain 2B

  7. calcium signaling mediated by NCX3 has a crucial role in oligodendrocyte maturation and myelin formation.

  8. Results show that glucocorticoid treatment blunts LPS (show TLR4 Proteins)-induced increase in [Ca(2 (show CA2 Proteins)+)](i) in dendritic cells by increasing expression and activity of Na(+)/Ca(2 (show CA2 Proteins)+) exchanger NCX3.

  9. The deletion of the NCX3 gene has detrimental consequences on basal synaptic transmission, long term potentiation regulation, spatial learning, and memory performance.

  10. These results showed significant expression of NCX1 (show SLC8A1 Proteins) and NCX3 in ameloblasts, indicating their involvement in the directional Ca(2 (show CA2 Proteins)+) extrusion pathway from cells to the enamel mineralizing front

Solute Carrier Family 8 (Sodium/calcium Exchanger), Member 3 (SLC8A3) Protein Profile

Protein Summary

This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Three mammalian isoforms in family 8 have been identified. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

Gene names and symbols associated with SLC8A3

  • solute carrier family 8 (sodium/calcium exchanger), member 3 (SLC8A3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (LOC100339605)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (slc8a3)
  • solute carrier family 8 (sodium/calcium exchanger), member 3 (Slc8a3)
  • AW742262 protein
  • Ncx3 protein
  • SLC8A3 protein

Protein level used designations for SLC8A3

solute carrier family 8 (sodium-calcium exchanger), member 3 , solute carrier family 8 member 3 , solute carrier family 8 (sodium/calcium exchanger), member 3 , sodium/calcium exchanger 3-like , Na(+)/Ca(2+)-exchange protein 3 , Na+/Ca2+ exchanger 3 , sodium/calcium exchanger 3 , sodium/calcium exchanger SLC8A3 , sodium-calcium exchanger

GENE ID SPECIES
467491 Pan troglodytes
490755 Canis lupus familiaris
100034161 Equus caballus
100152101 Sus scrofa
100339605 Oryctolagus cuniculus
100412630 Callithrix jacchus
100471755 Ailuropoda melanoleuca
100487508 Xenopus (Silurana) tropicalis
100541915 Meleagris gallopavo
100603298 Nomascus leucogenys
6547 Homo sapiens
140448 Rattus norvegicus
540307 Bos taurus
110893 Mus musculus
395759 Gallus gallus
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