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anti-Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) Antibodies

SLC9A1 encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. Additionally we are shipping Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Proteins (6) and Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC9A1 20544 Q61165
SLC9A1 6548 P19634
SLC9A1 24782 P26431
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Top anti-Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemical staining of human brain tissue using AP30591PU-N at 2.5 μg/ml. Western blot analysis of Nhe-1 in rat kidney tissue lysate with in with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemical staining of human brain tissue using AP30592PU-N at 2.5 μg/ml. Western blot analysis of Nhe-1 in MOLT4 cell lysate with this product at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 10 blots Log in to see 6 to 8 Days
$533.50
Details
Dog Mouse Un-conjugated IF, WB Western blot analysis for NHE on a HEK-293 cell lysate (Human embryonic kidney cells, ATCC CRL-1573). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the Mouse Anti-NHE antibody. Immunofluorescence staining of NIH/3T3 cells (Mouse embryo fibroblast cells, ATCC CRL-1658). 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SLC9A1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate WB Suggested Anti-SLC9A1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: PANC1 cell lysate  SLC9A1 is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Log in to see 2 to 3 Days
$289.00
Details
Arabidopsis thaliana Rabbit Un-conjugated ELISA, WB 1ug and 10ug of crude membrane fraction/lane from Arabidopsis thaliana (left panel) and 1,5 and 10ug of crude membrane fraction/lane Raphanussativus L. (right panel) were separated on 12 % SDS-PAGE and blotted 1h toPVDF membrane (40 min. at 10 V using BioRad semidry transfer). Filters wereblocked 1h with 5 % low-fat milk powder in TBS-T (0.05% Triton X.100).Membranes were washed 5 times with TBS-T, each time in a fresh polystyrenebox and probed with anti-NHX antibodies (ABIN349668, 1:1000, 1h) and secondaryanti-rabbit (1:2000, 1 h). All steps were performed in RT with agitation. 100 μL Log in to see 5 to 6 Days
$526.68
Details
Mammalian Mouse Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$863.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-SLC9A1 Picoband antibody,  All lanes: Anti SLC9A1  at 0.5ug/ml Lane 1: PC-12 Whole Cell Lysate at 40ug Lane 2: MCF-7 Whole Cell Lysate at 40ug Predicted bind size: 91KD Observed bind size: 91KD Anti-SLC9A1 Picoband antibody,  IHC(P): Mouse Kidney Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Rat Chicken Un-conjugated ELISA, WB   50 μg Log in to see 8 to 10 Days
$610.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 rat brain, L2 rat liver lysates probed (ABIN669426) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band and observed band size: 91kDa. 100 μL Log in to see 3 to 7 Days
$269.50
Details

SLC9A1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Antibodies

  1. Dog (Canine) Monoclonal SLC9A1 Primary Antibody for IF, WB - ABIN968659 : Aharonovitz, Zaun, Balla, York, Orlowski, Grinstein: Intracellular pH regulation by Na(+)/H(+) exchange requires phosphatidylinositol 4,5-bisphosphate. in The Journal of cell biology 2000 (PubMed)
    Show all 5 references for ABIN968659

  2. Human Polyclonal SLC9A1 Primary Antibody for WB - ABIN265247 : Pang, Wakabayashi, Shigekawa: Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 references for ABIN265247

  3. Human Polyclonal SLC9A1 Primary Antibody for EIA, IHC (p) - ABIN500339 : Mendoza: The Na+-H+ antiport is a mediator of cell proliferation. in Acta paediatrica Scandinavica 1987 (PubMed)
    Show all 2 references for ABIN500339

  4. Mammalian Monoclonal SLC9A1 Primary Antibody for WB - ABIN180918 : Rutherford, Pizzonia, Biemesderfer, Abu-Alfa, Reilly, Aronson: Expression of Na(+)-H+ exchanger isoforms NHE1 and NHE3 in kidney and blood cells of rabbit and rat. in Experimental nephrology 1998 (PubMed)

  5. Arabidopsis thaliana Polyclonal SLC9A1 Primary Antibody for ELISA, WB - ABIN349668 : Chen, Xiao, Wu, Dong, He, Pei, Zheng: Nitric oxide enhances salt secretion and Na(+) sequestration in a mangrove plant, Avicennia marina, through increasing the expression of H(+)-ATPase and Na(+)/H(+) antiporter under high salinity. in Tree physiology 2010 (PubMed)

More Antibodies against Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 Interaction Partners

Arabidopsis thaliana Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. Tonoplast-localized NHX1 and NHX2 proteins are essential for active K+ uptake at the tonoplast, for turgor regulation, and for stomatal function.

  2. Overexpression of AtNHX1 gene not only improved salt tolerance but also drought tolerance in transgenic groundnut.

  3. NHX1 and NHX2 mediate K+/H+ exchange to accumulate K+ in the vacuole. NHX1 and NHX2 function together to control cell expansion in vegetative tissues and male reproductive organs and are required for normal flower development.

  4. Studies shoe that the rutin content of the roots, stems and leaves of AtNHX1 transgenic buckwheat increased than those of the control plants.

  5. Use of the T-DNA insertional mutant of AtNHX1 (nhx1 plants) and DNA arrays to assess differences in transcriptional profiles and further characterize the roles of this protein.

  6. the presence of a vacuolar calmodulin-like (show KRIT1 Antibodies) protein acting on the vacuolar-localized AtNHX1 C terminus in a Ca(2 (show CA2 Antibodies)+)- pH-dependent manner suggests the presence of signaling entities acting within the vacuole.

  7. AtNHX1 has a role in calcium signaling, sulfur metabolism, cell structure and cell growth, as well as vesicular trafficking and protein processing.

  8. To generate salt-tolerant turf and forage, tall fescue (Festuca arundinacea) was transformed with AtNHX1.

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. During hypoxia, activation of ROCK enhances NHE1 activity and promotes pulmonary artery smooth muscle cell migration and proliferation.

  2. Na/H exchanger is regulated in dendritic cells by Akt1 (show AKT1 Antibodies).

  3. our results suggest that activation of NHE1 induces hypertrophy through the activation of NFAT3 (show NFATC4 Antibodies)/Gata4 (show GATA4 Antibodies) and OPN (show SPP1 Antibodies) expression

  4. NHE1 function is necessary for maintaining mammary branched architecture.

  5. the extracellular matrix (ECM (show MMRN1 Antibodies)) composition strongly impacts on NHE1-dependent in vitro cell motility and invasion

  6. long-term ablation of NHE1 activity increases the redox potential, mitigates high-fat diet-induced myocardial stress.

  7. study shows that NHE-1 protein is abundantly expressed in microglial lamellipodia and maintains alkaline pHi in response to BK stimulation

  8. exerts a protective effect by reducing the loss of synaptopodin (show SYNPO Antibodies) in podocytes exposed to endoplasmic reticulum stress

  9. NHE1 functions as a metabolic sensor for lipotoxicity.

  10. PDGFRalpha signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1 (show MAP2K1 Antibodies)/2-ERK1/2 (show MAPK1/3 Antibodies)-p90RSK (show RPS6KA1 Antibodies) and AKT (show AKT1 Antibodies) signaling pathways.

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. This study evaluated the role for NHE-1 in diabetic cataract formation and retinal oxidative stress and apoptosis.

  2. Results support the hypothesis that a blood-brain barrier Na/H exchanger, possibly NHE1 and/or NHE2 (show SLC9A2 Antibodies), is stimulated during ischemia to participate in cerebral edema formation.

Pig (Porcine) Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. NHE isoform switching and KChIP2 (show KCNIP2 Antibodies) upregulation takes place in aging porcine atria.

  2. NHE-1 inhibitor cariporide attenuates skeletal muscle infarction when administered before ischemia or reperfusion.

Human Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. Human NHE1 acts as an ERK2 (show MAPK1 Antibodies) membrane protein scaffold in vivo that is necessary for ERK2 (show MAPK1 Antibodies) activation via direct interactions, and loss of scaffolding by NHE1 leads to decreased ERK2 (show MAPK1 Antibodies) activation.

  2. interaction of NHE1, NCX1 (show SLC8A1 Antibodies) and CaM (show CALM1 Antibodies) mediates the effects of IL6 (show IL6 Antibodies) on human hepatocellular carcinoma

  3. the present study revealed that miR (show MLXIP Antibodies)-27b is upregulated by HPV16 E7 to inhibit PPARg (show PPARG Antibodies) expression and promotes proliferation and invasion in cervical carcinoma cells.

  4. The NHE-1 is a ubiquitously expressed cell membrane protein which regulates intracellular pH (pH(i)) and extracellular pH (pH(e)) homeostasis and cell volume.

  5. Functional studies of N266H mutation in SLC9A1 gene showed a minor effect on the level of expression and no effect on targeting of the protein, however there was a complete absence of SLC9A1 activity.

  6. PKC-delta (show PKCd Antibodies) activates p38/MAPK (show MAPK14 Antibodies), responsible for the inhibition of MMP-2 (show MMP2 Antibodies) and -9 secretion, PKC-epsilon (show PRKCE Antibodies) activates a pathway made of ERK1/2 (show MAPK1/3 Antibodies), mTOR (show FRAP1 Antibodies) and S6K (show RPS6KB1 Antibodies) responsible for the inhibition of NHE1 activity and cell migration.

  7. Data suggest that Na/H exchanger isoform one (NHE1) is critical in triple-negative breast cancer metastasis.

  8. Importantly, the specific NHE1 inhibitor cariporide reduced both three-dimensional growth and invasion independently of PDAC subtype and synergistically sensitized these behaviors to low doses of erlotinib.

  9. Concurrent speed endurance and resistance training increases skeletal muscle NHE1 activity.

  10. Mutation of SLC9A1 is associated with ataxia (show USP14 Antibodies)-deafness Lichtenstein-Knorr syndrome.

Rabbit Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) interaction partners

  1. In vitro phosphorylation of NHE1 C-terminal fusion proteins determined that ERK (show MAPK1 Antibodies)-dependent phosphorylation of the cytoplasmic region was not dependent on Ser (show SIGLEC1 Antibodies)(703); however, phosphorylation by p90(rsk (show RPS6KA1 Antibodies)) required Ser (show SIGLEC1 Antibodies)(703).

Solute Carrier Family 9, Subfamily A (NHE1, Cation Proton Antiporter 1), Member 1 (SLC9A1) Antigen Profile

Protein Summary

This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth.

Gene names and symbols associated with SLC9A1

  • sodium/hydrogen exchanger 1 (NHX1) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 1 (Slc9a1) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 1 (SLC9A1) antibody
  • solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (SLC9A1) antibody
  • solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 (Slc9a1) antibody
  • APNH antibody
  • AT-NHX1 antibody
  • ATNHX antibody
  • ATNHX1 antibody
  • AW554487 antibody
  • NA(+)/H(+) ANTIPORTER antibody
  • Na+/H+ exchanger 1 antibody
  • NHE-1 antibody
  • NHE1 antibody
  • swe antibody
  • T21B4.60 antibody
  • T21B4_60 antibody

Protein level used designations for SLC9A1

NHE-1 , Na(+)/H(+) exchanger 1 , Na+/H+ antiporter , Na+/H+, amiloride sensitive , slow-wave epilepsy , sodium/hydrogen exchanger 1 , solute carrier family 9 member 1 , solute carrier family 9, member 1 , sodium proton exchanger , solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive) , solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) , Solute carrier family 9 member 1 , NA(+)-H+ exchanger protein , Na-Li countertransporter , Solute carrier family 9 (sodium/hydrogen exchanger 1), antiporter, Na+/H+, (amiloride sensitive) , solute carrier family 9 (sodium/hydrogen exchanger), member 1 , Na+/H+ exchanger , pH regulatory protein (Na(+) /H(+) exchanger)

GENE ID SPECIES
832773 Arabidopsis thaliana
20544 Mus musculus
317654 Bos taurus
100689320 Cricetulus griseus
397458 Sus scrofa
6548 Homo sapiens
24782 Rattus norvegicus
419580 Gallus gallus
478171 Canis lupus familiaris
100009586 Oryctolagus cuniculus
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