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Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins (SLC9A3R1)

SLC9A3R1 encodes a sodium/hydrogen exchanger regulatory cofactor. Additionally we are shipping Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Antibodies (84) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC9A3R1 26941 P70441
SLC9A3R1 9368 O14745
SLC9A3R1 59114 Q9JJ19
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Top Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,968.17
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Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
$2,973.67
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Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,973.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,004.83
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HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

SLC9A3R1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Interaction Partners

Mouse (Murine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. These results indicate that PTH (show PTH Proteins)-mediated inhibition of renal phosphate transport involves phosphorylation of S77 of the NHERF-1 PDZ I domain and the dissociation of NHERF-1/Npt2a (show SLC34A1 Proteins) complexes.

  2. Results strongly support an important role for NHERF1 (show SLC9A3R2 Proteins) in the regulation of Planar Cell Polarity signaling and the development of functional motile cilia.

  3. the activation of PTEN and NHERF-1 may impede the evolution of macrophages beyond the M1 into M2 phenotype in tumor microenvironment.

  4. Data show that interaction of the inducible nitric oxide synthase (iNOS (show NOS2 Proteins)) C-terminus with the PDZ domains of EBP50 protein or Pdzk1 (show PDZK1 Proteins) protein CAP70 (show PDZK1 Proteins) resulted greater nitric oxide (NO) synthesis.

  5. The expression of EBP50 was not significantly different in the pseudopregnant uterus and decreased in the uteri subjected to activation of delayed implantation.

  6. NHERF1 (show SLC9A3R2 Proteins) is differentially distributed to rafts and non-raft brush border membrane fractions of NHE3 (show SLC9A3 Proteins).

  7. EBP50 expression is induced by inflammatory stimuli and potentiates NF-kappaB (show NFKB1 Proteins) activation and inflammation in primary macrophages and VSMC.

  8. siRNA knockdown of PEX7 (show PEX7 Proteins) reduced iNOS (show NOS2 Proteins) colocalization with the peroxisomal protein (show FNDC5 Proteins) PMP70 (show ABCD3 Proteins). Proteomic studies using MALDI-MS identified iNOS (show NOS2 Proteins) association with the 50-kD ezrin (show EZR Proteins) binding PDZ protein (EBP50).

  9. EBP50 promotes focal adhesion turnover and vascular smooth muscle cells migration.

  10. NHERF1 (show SLC9A3R2 Proteins) regulates PTH (show PTH Proteins) that differentially affects Na-dependent Pi transport at distinct stages of osteoblast proliferation and maturation

Cow (Bovine) Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. study found mainly nuclear localization of EBP50 in interphase cells, and its redistribution to cytoplasm during mitosis parallel with its phosphorylation; PP2A (show PPP2R2B Proteins) was identified as an interacting protein of EBP50 during pro-, prometa-, meta-, ana (show BTG3 Proteins)-, telophase, and early cytokinesis

Human Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) interaction partners

  1. Results showed that EBP50 specifically scaffolds the interaction of PTEN with EGFR (show EGFR Proteins) and enhances the inhibition of PTEN on EGF (show EGF Proteins)-induced AKT (show AKT1 Proteins) activation. These results elucidated a novel mechanism regulating EGF (show EGF Proteins)-induced AKT (show AKT1 Proteins) signaling.

  2. autosomal-dominant polycystic kidney disease is associated with a decrease in NHERF1 protein and mRNA levels.

  3. Interaction of ABCB4 (show ABCB4 Proteins) with EBP50 through its PDZ-like motif plays a critical role in the regulation of ABCB4 (show ABCB4 Proteins) expression and stability at the canalicular plasma membrane.

  4. This study identified alpha-actinin-4 (show ACTN4 Proteins) as a novel NHERF1 interaction partner and provided new insights into the regulatory mechanism of the actin cytoskeleton by NHERF1.

  5. deuterium uptake profiles of isolated PDZ1 and PDZ2 were similar to those of full-length EBP50. Interestingly, PDZ1 was more dynamic than PDZ2, and these PDZ domains underwent different conformational changes upon ligand binding

  6. Nuclear NHERF1 expression is associated with drug resistance in in advanced gastric cancer patients treated with epirubicin/oxaliplatin/capecitabine first line chemotherapy.

  7. These data highlight a role for NHERF1 in ependymal morphogenesis with direct application to the diagnosis of ependymal tumors.

  8. activation of the Nherf1-PP1alpha (show PPP1CA Proteins)-TAZ (show TAZ Proteins) pathway in osteoblasts is targeted by histone deacetylase (show HDAC1 Proteins) inhibitors

  9. conclude that FNACs provide useful material for detection of NHERF1 localization and expression, and that high nuclear NHERF1 expression may be a potential marker of aggressiveness in NSCLC

  10. A molecular switch in the scaffold NHERF1 enables misfolded CFTR (show CFTR Proteins) to evade the peripheral quality control checkpoint.

Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1) Protein Profile

Protein Summary

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.

Gene names and symbols associated with SLC9A3R1

  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (Slc9a3r1)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (SLC9A3R1)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 (Slc9a3r1)
  • EBP-50 protein
  • EBP50 protein
  • NHE-RF protein
  • NHERF protein
  • NHERF-1 protein
  • NHERF1 protein
  • NPHLOP2 protein

Protein level used designations for SLC9A3R1

EBP50 , Na(+)/H(+) exchange regulatory cofactor NHE-RF1 , ezrin-radixin-moesin-binding phosphoprotein 50 , regulatory cofactor of Na(+)/H(+) exchanger , sodium-hydrogen exchanger regulatory factor 1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1 , solute carrier family 9 isoform A3 regulatory factor 1 , Na(+)/H(+) exchange regulatory cofactor NHE-RF , ezrin-radixin-moesin binding phosphoprotein-50 , solute carrier family 9 isoform 3 regulatory factor 1 , Na+/H+ exchange regulatory co-factor , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1 , NHERF-1 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 , ERM-binding phosphoprotein

GENE ID SPECIES
26941 Mus musculus
505242 Bos taurus
9368 Homo sapiens
422108 Gallus gallus
59114 Rattus norvegicus
100009196 Oryctolagus cuniculus
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