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Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Proteins (SLC9A3)

displays Na+/H+ exchanger transport activity\; mediates sodium ion transport across the renal proximal tubule [RGD, Feb 2006].. Additionally we are shipping SLC9A3 Antibodies (75) and SLC9A3 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC9A3 105243  
SLC9A3 24784 P26433
SLC9A3 6550 P48764
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Top SLC9A3 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details

SLC9A3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Rat (Rattus)
Human , ,
, ,

More Proteins for Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) Interaction Partners

Cow (Bovine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) interaction partners

  1. The expression of NHE3 in the rumen of sheep and cattle and its role in sodium transport are reported.

Rabbit Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) interaction partners

  1. Lysophosphatidic acid stimulation of NHE3 exocytosis includes a signaling pathway that regulates fixation of NHE3 to the microvillar cytoskeleton.

  2. 1) NHE3 basal activity is regulated by a signaling complex that is controlled by sequential effects of two kinases, Akt (show AKT1 Proteins) and GSK-3, which act on a Ser (show SIGLEC1 Proteins) cluster in the same NHE3 C-terminal domain that binds ezrin (show EZR Proteins)

  3. CaMKII (show CAMK2G Proteins) binding to and phosphorylation of the NHE3 C terminus are parts of the physiologic regulation of NHE3 that occurs in fibroblasts as well as in the brush border of an intestinal Na(+)-absorptive cell.

  4. Regulation of NHE3 depends on the nature of the NHERF (show SLC9A3R1 Proteins) family member associating with NHE3 and the accompanying NHE3 complexes.

Mouse (Murine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) interaction partners

  1. azilsartan (but not candesartan) improved salt sensitivity possibly by decreasing NHE3 expression via ubiquitin-proteasomal degradation.

  2. NHE3 in proximal tubules of the kidney, along with NHE3 in intestines, is required for maintaining basal blood pressure as well as the full development of ANG II (show AGT Proteins)-induced hypertension.

  3. Inflammation-induced loss of PDZK1 (show PDZK1 Proteins) expression may contribute to the NHE3 dysfunction observed in the inflamed intestine.

  4. these findings indicate the importance of NHE3 in diabetic diarrhea and suggest LPA administration as a potential therapeutic strategy for management of diabetic diarrhea.

  5. Myosin VI (show MYO6 Proteins) mediates the movement of NHE3 to the microvillus in intestinal epithelial cells.

  6. Cyclic GMP kinase (show GUK1 Proteins) II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites

  7. Both NHE3 and NHE8 likely play a role in neonatal acidification.

  8. NHE3 partially associates with lipid rafts in the brush border membrane.

  9. The gut (show GUSB Proteins) microbiome plays a prominent role in the pathogenesis of colitis in NHE3 knockout mice, and, reciprocally, NHE3 also plays a critical role in shaping the gut (show GUSB Proteins) microbiota.

  10. Saline drinking significantly enhanced fluid intake and increased NHE3 transcript levels in the jejunum.

Human Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) interaction partners

  1. Recessive mutations in NHE3, a downstream target of GC-C (show GUCY2C Proteins), caused congenital sodium diarrhea and implied primary basal NHE3 malfunction as a predisposition for inflammatory bowel disease in a subset of patients.

  2. CCH-mediated inhibition of NHE3 activity is not dependent on clathrin and involves lipid rafts and requires Cdc42 (show CDC42 Proteins).

  3. Inflammation-induced loss of PDZK1 (show PDZK1 Proteins) expression may contribute to the NHE3 dysfunction observed in the inflamed intestine.

  4. Data demonstrate a role for Per1 in the transcriptional regulation of NHE3 and SGLT1 (show SLC5A1 Proteins) in the kidney.

  5. Results demonstrate decreased transport activity in three SNPs of NHE3 and provide mechanistic insight into how these SNPs impact NHE3 function.

  6. these findings indicate the importance of NHE3 in diabetic diarrhea and suggest LPA administration as a potential therapeutic strategy for management of diabetic diarrhea.

  7. NHE3 may play a role in the pathogenesis of human cholesterol gallstone disease

  8. Study identifies RSK2 (show RPS6KA3 Proteins) as a new kinase that regulates NHE3 activity by direct phosphorylation.

  9. the three NHE3 SNPs are unlikely to play a major role in the pathogenesis of SIDS (show IDS Proteins) in Caucasian infants;further genetic investigations in different ethnicities are required to determine whether variations in NHE3 are associated with an increased SIDS (show IDS Proteins) risk

  10. C. difficile inhibits NHE3 in vivo, which creates an altered environment favored by C. difficile.

Pig (Porcine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 (SLC9A3) interaction partners

  1. We propose that ouabain can simultaneously regulate renal tubule basolateral Na(+)-K(+)-ATPase (show ATP1A1 Proteins) and apical NHE3, leading to inhibition of transepithelial Na(+) transport.

SLC9A3 Protein Profile

Protein Summary

displays Na+/H+ exchanger transport activity\; mediates sodium ion transport across the renal proximal tubule

Gene names and symbols associated with SLC9A3

  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 (SLC9A3)
  • sodium/hydrogen exchanger 3 (nhe3) (AaeL_AAEL001503)
  • Sodium/hydrogen exchanger 3 (GL50803_102647)
  • sodium/hydrogen exchanger 3 (nhe3) (Smp_045680)
  • Na/H exchanger 3 (NHE-3)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 (Slc9a3)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 (Slc9a3)
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 (SLC9A3)
  • 9030624O13Rik protein
  • AI930210 protein
  • NHE-3 protein
  • Nhe3 protein
  • SLC9A3 protein

Protein level used designations for SLC9A3

sodium proton exchanger , sodium/hydrogen exchanger 3 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 , sodium/hydrogen exchanger 3 (nhe3) , Sodium/hydrogen exchanger 3 , Na(+)/H(+) exchanger 3 , Na+/H+ exchanger homolog , solute carrier family 9 member 3 , NHE-3 , Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive) , plasma membrane ion transport protein , solute carrier family 9, member 3 , solute carrier family 9 (sodium/hydrogen exchanger) , sodium/hydrogen exchanger

GENE ID SPECIES
407112 Bos taurus
420801 Gallus gallus
5570922 Aedes aegypti
5698518 Giardia lamblia ATCC 50803
8348267 Schistosoma mansoni
100009430 Oryctolagus cuniculus
105243 Mus musculus
24784 Rattus norvegicus
6550 Homo sapiens
397358 Sus scrofa
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