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anti-Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) Antibodies

SLC9A3R2 encodes a member of the NHERF family of PDZ scaffolding proteins. Additionally we are shipping Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLC9A3R2 65962 Q9JHL1
SLC9A3R2 9351 Q15599
SLC9A3R2 116501 Q920G2
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Top anti-Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IP, WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Slc9a3r2 AntibodyTitration: 1.0 µg/mL  Positive Control: Rat Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB WB Image Sample (50 ug of whole cell lysate) A: mouse liver 15% SDS PAGE antibody diluted at 1:1000 WB Image NHERF-2 antibody detects NHERF-2 protein by western blot analysis. Whole cell extracts (30 μg) was separated by 10 % SDS-PAGE, and blotted with NHERF-2 antibody , diluted by 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated EIA, WB Antibody (1µg/ml) staining of Daudi lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$507.83
Details

SLC9A3R2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Human ,
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Rat (Rattus) ,
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Top referenced anti-Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 Antibodies

  1. Human Polyclonal SLC9A3R2 Primary Antibody for ELISA, WB - ABIN185495 : Cha, Kim, Hut, Hogema, Nadarja, Zizak, Cavet, Lee-Kwon, Lohmann, Smolenski, Tse, Yun, de Jonge, Donowitz: cGMP inhibition of Na+/H+ antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein. in The Journal of biological chemistry 2005 (PubMed)

  2. Human Monoclonal SLC9A3R2 Primary Antibody for IP, WB - ABIN1169696 : Theisen, Wahl, Johnson, Wheelock: NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility. in Molecular biology of the cell 2007 (PubMed)

More Antibodies against Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 Interaction Partners

Zebrafish Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) interaction partners

  1. Results strongly support an important role for NHERF1 in the regulation of Planar Cell Polarity signaling and the development of functional motile cilia.

Cow (Bovine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) interaction partners

  1. the essential role of NHERF2 in endothelial cell adhesion/migration and angiogenesis. [NHERF2]

Pig (Porcine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) interaction partners

  1. Analysis showed that SLC9A3R2 gene has the closest genetic relationship with the SLC9A3R2 gene of human; it is structured in 7 exons and 6 introns; tissue expression analysis indicated that SLC9A3R2 gene is differentially expressed in different tissues.

Mouse (Murine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) interaction partners

  1. NHERF2 is differentially distributed to lipid rafts in brush border membrane fractions of NHE3 (show SLC9A3 Antibodies).

  2. involvement of NHERF2 in multiple apical regulatory processes and interactions with luminal contents

  3. NHERF2 is necessary for multiple aspects of acute regulation of NHE3 (show SLC9A3 Antibodies) in intact mouse small intestine

  4. It was concluded that NHERF2 plays important roles in tethering NHE3 (show SLC9A3 Antibodies) to a position near the terminal web and in second messenger inhibition of NHE3 (show SLC9A3 Antibodies) in a signal- and segment-specific fashion.

  5. Lysophosphatidic acid (LPA) is a potent stimulant of NHE3 (show SLC9A3 Antibodies) and fluid absorption in the intestine, signaling through LPA(5 (show LPAR5 Antibodies)). Regulation by LPA(5 (show LPAR5 Antibodies)) depends on its interaction with NHERF2.

  6. demonstration of the significance of SGK1 (show SGK1 Antibodies) and NHERF2 as TRPV5 (show TRPV5 Antibodies) modulators which are likely to participate in the regulation of calcium homeostasis by 1,25(OH)2D3

  7. the function of SIP-1/NHERF2 as an SRY (show SRY Antibodies) cofactor during testis determination is conserved between human and mouse

  8. analysis of NHERF (show SLC9A3R1 Antibodies) recognition by ERM (show ETV5 Antibodies) proteins

  9. NHERF-2 and mGluR5 (show GRM5 Antibodies) exhibit overlapping patterns of expression in mouse brain, where their association prolongs intracellular calcium mobilization by mGluR5 (show GRM5 Antibodies) and promotes mGluR5 (show GRM5 Antibodies)-mediated toxicity.

  10. NHERF-1 (show SLC9A3R1 Antibodies) but not NHERF-2 in native intestinal epithelium is involved in the formation of CFTR (show CFTR Antibodies)-containing functional complexes that serve to position CFTR (show CFTR Antibodies) in the crypt apical membrane and to optimize its function as a cAMP- and cGMP-regulated anion channel

Human Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) interaction partners

  1. Moreover, the S303D mutation enhances the in vivo dynamics of the E3KARP tail alone, whereas in vitro the interaction of E3KARP with active ezrin (show EZR Antibodies) is unaffected by S303D

  2. Lysophosphatidic acid stimulation of NHE3 (show SLC9A3 Antibodies) exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK (show EPHB2 Antibodies)-PLC (show HSPG2 Antibodies)-PKCdelta (show PKCd Antibodies) signaling.

  3. Data indicate that the tails promote different microvillar localizations for EBP50 (show SLC9A3R1 Antibodies) and E3KARP, which localized along the full length and to the base of microvilli, respectively.

  4. Crystal structure of NHERF2 PDZ1 domain complex with C-terminal LPA2 (show LPAR2 Antibodies) sequence. The PDZ1-LPA2 (show LPAR2 Antibodies) binding specificity is achieved by hydrogen bonds and hydrophobic contacts with the last four LPA2 (show LPAR2 Antibodies) residues contributing to specific interactions.

  5. NHERF2 domain was functionally significant in NHE3 (show SLC9A3 Antibodies) regulation, being necessary for stimulation by lysophosphatidic acid of activity and increased mobility of NHE3 (show SLC9A3 Antibodies)

  6. functional regulation of C3aR (show C3AR1 Antibodies) by NHERFs in human mast cells

  7. AnxA2 (show ANXA2 Antibodies) and NHERF2 form a scaffold complex that links adjacent Tir molecules at the plasma membrane forming a lattice that could be involved in retention and dissemination of other effectors at the bacterial attachment site.

  8. NHERF-2 is a negative regulator of endothelial proliferation and may have important roles in endothelial homeostasis and vascular modeling.

  9. CaMKII (show CAMK2G Antibodies) inhibition of NHE3 (show SLC9A3 Antibodies) reguires NHEF2.

  10. Data show that both NHERF2 and NHERF1 (show SLC9A3R1 Antibodies) are involved in setting NHE3 (show SLC9A3 Antibodies) activity.

Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 3 Regulator 2 (SLC9A3R2) Antigen Profile

Protein Summary

This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with SLC9A3R2

  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 (slc9a3r1) antibody
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 (SLC9A3R2) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (SLC9A3R2) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 (Slc9a3r2) antibody
  • solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 (Slc9a3r2) antibody
  • 0610011L07Rik antibody
  • 1200011K07Rik antibody
  • 2010007A20Rik antibody
  • cb895 antibody
  • E3KARP antibody
  • NHE3RF2 antibody
  • NHERF-2 antibody
  • NHERF2 antibody
  • OCTS2 antibody
  • SIP-1 antibody
  • SIP1 antibody
  • slc9a3r2 antibody
  • Sryip1 antibody
  • TKA-1 antibody
  • wu:fd20a02 antibody
  • zgc:55541 antibody
  • zgc:77629 antibody

Protein level used designations for SLC9A3R2

Na(+)/H(+) exchange regulatory cofactor NHE-RF1 , nherf1 , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2 , solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 , Na(+)/H(+) exchange regulatory cofactor NHE-RF2 , solute carrier family 9 isoform 3 regulator 2 , NHE3 kinase A regulatory protein E3KARP , SRY-interacting protein 1 , Sry interacting protein 1 , sodium-hydrogen exchanger regulatory factor 2 , sodium/hydrogen exchanger , solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2 , solute carrier family 9 isoform 3 regulator 2, isoform A; sodium/hydrogen exchanger , solute carrier family 9 isoform A3 regulatory factor 2 , tyrosine kinase activator protein 1 , NHE3 regulatory factor 2 , sodium/hydrogen exchanger 3 kinase A regulatory protein , NHERF-2 , SIP-1 , TKA-1 , PDZ domain containing protein NHERF-2 , PDZ domain-containing protein NHERF-2

GENE ID SPECIES
327272 Danio rerio
416550 Gallus gallus
479884 Canis lupus familiaris
694658 Macaca mulatta
768005 Bos taurus
100192448 Sus scrofa
65962 Mus musculus
9351 Homo sapiens
116501 Rattus norvegicus
100008813 Oryctolagus cuniculus
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