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Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 Proteins (SLC9A4)

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Additionally we are shipping SLC9A4 Antibodies (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SLC9A4 110895 Q8BUE1
SLC9A4 389015 Q6AI14
Rat SLC9A4 SLC9A4 24785 P26434
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Top SLC9A4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details

SLC9A4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
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More Proteins for Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4) Interaction Partners

Mouse (Murine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4) interaction partners

  1. Disruption of murine NHE4 leads to metabolic acidosis with inappropriate urinary ammonia excretion and decreases the ability of the thick ascending limb to absorb ammonia and to build the corticopapillary ammonia gradient.

  2. NHE4, which may normally be coupled with the AE2 (show SLC4A2 Proteins) Cl-/HCO3- exchanger, is important for normal levels of gastric acid secretion, gastric epithelial cell differentiation, and development of secretory canalicular and tubulovesicular membranes

  3. Dra (show SLC26A3 Proteins) is the major Cl(-)/HCO(3)(-) exchanger coupled with Nhe3 (show SLC9A3 Proteins) for electroneutral NaCl absorption across mammalian small intestine.

Human Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 4 (SLC9A4) interaction partners

  1. Data demonstrate functional NHE4 activity in the rat and human colon and suggest that this exchanger is capable of modulating intracellular pH over a wide pH spectrum and may play an important role in maintaining cellular pH homeostasis.

  2. T84 human colon cells contain three isoforms of the Na+/H+ exchanger, NHE1 (show SLC9A1 Proteins), NHE2, and NHE4, but not the Cl-dependent NHE

SLC9A4 Protein Profile

Protein Summary

Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. May play a specialized role in the kidney in rectifying cell volume in response to extreme fluctuations of hyperosmolar-stimulated cell shrinkage. Is relatively amiloride and ethylisopropylamiloride (EIPA) insensitive. Can be activated under conditions of hyperosmolar-induced cell shrinkage in a sustained intracellular acidification-dependence manner. Activated by 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) in a sustained intracellular acidification-dependence manner. Affects potassium/proton exchange as well as sodium/proton and lithium/proton exchange. In basolateral cell membrane, participates in homeostatic control of intracellular pH, and may play a role in proton extrusion in order to achieve transepithelial HCO3(-) secretion. In apical cell membrane may be involved in mediating sodium absorption. Requires for normal levels of gastric acid secretion, secretory membrane development, parietal cell maturation and/or differentiation and at least secondarily for chief cell differentiation.

Gene names and symbols associated with SLC9A4

  • solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 (SLC9A4)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 4 (SLC9A4)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 4 (slc9a4)
  • solute carrier family 9 (sodium/hydrogen exchanger), member 4 (Slc9a4)
  • solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 (Slc9a4)
  • AW990558 protein
  • D730009J23Rik protein
  • Nhe4 protein
  • SLC9A2 protein

Protein level used designations for SLC9A4

solute carrier family 9 (sodium/hydrogen exchanger), member 4 , Na+/H+ exchanger , solute carrier family 9 (sodium/hydrogen exchanger), member 2 , sodium/hydrogen exchanger 4-like , NHE-4 , Na(+)/H(+) exchanger 4 , sodium/hydrogen exchanger 4 , solute carrier family 9 member 4 , solute carrier family 9 (sodium/hydrogen exchanger) , Solute carrier family 9 (sodium/hydrogen exchanger) , solute carrier family 9 (sodium/hydrogen exchanger) isoform 4 , solute carrier family 9, member 4

GENE ID SPECIES
396786 Sus scrofa
418718 Gallus gallus
536970 Bos taurus
744316 Pan troglodytes
100058138 Equus caballus
100343035 Oryctolagus cuniculus
100473417 Ailuropoda melanoleuca
100491047 Xenopus (Silurana) tropicalis
100543135 Meleagris gallopavo
100589113 Nomascus leucogenys
110895 Mus musculus
389015 Homo sapiens
24785 Rattus norvegicus
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