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Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 6 (SLC9A6) ELISA Kits

SLC9A6 encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. Additionally we are shipping SLC9A6 Antibodies (28) and SLC9A6 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SLC9A6 SLC9A6 236794  
Anti-Rat SLC9A6 SLC9A6 302863  
Anti-Human SLC9A6 SLC9A6 10479 Q92581
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More ELISA Kits for SLC9A6 Interaction Partners

Mouse (Murine) Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 6 (SLC9A6) interaction partners

  1. analysis of the heterozygous Slc9a6 KO female mice model of X-linked Christianson syndrome

  2. deletion of (370)Trp-Ser-Thr(372) leads to endoplasmic reticulum retention and loss of NHE6 function

  3. Loss of NHE6 results in overacidification of the endosomal compartment and attenuated TrkB (show NTRK2 ELISA Kits) signaling.

  4. NHE6 may play a unique, previously unrecognized, role at glutamatergic synapses that are important for learning and memory

  5. Sodium-hydrogen exchanger 6 depletion leads to abnormal accumulation of GM2 (show CYB5D2 ELISA Kits) ganglioside and unesterified cholesterol within late endosomes and lysosomes of neurons in selective brain regions.

  6. This review describes Nhe6 knockout mice, which partially mimic phenotypical features of patients suffering from mental disorders including motor hyperactivity and a lowered threshold for pharmacologically induced seizures.

  7. NHE6 is expressed in the inner ear

Human Solute Carrier Family 9 (Sodium/hydrogen Exchanger), Member 6 (SLC9A6) interaction partners

  1. Epileptic encephalopathy related to mutations in the SLC9A6 genes.

  2. Data show that co-expression with sodium-hydrogen antiporter NHE6 or treatment with the Na(+)/H(+) ionophore monensin shifted amyloid precursor protein (APP (show APP ELISA Kits)) away from the trans-Golgi network into early and recycling endosomes in HEK293 cells.

  3. This study demonistrated that Genetic and phenotypic diversity of NHE6 mutations in Christianson syndrome.

  4. find interesting gene expression changes in endosomal NHE6 and NHE9 in postmortem autism brains.

  5. Data indicate SLC9A6 mutations and the clinical uniformity of male patients with Christianson syndrome in two familieis.

  6. We report on a 22year-old male patient with Christianson syndrome carrying the novel p.Gln306X mutation in SLC9A6

  7. The involvement of SLC9A6 mutations in 22 males initially suspected to have Angelman syndrome (show ube3a ELISA Kits) (AS) but found on genetic testing not to have AS (AS-like cohort), and 104 male patients with X-linked mental retardation (XMR) (XMR cohort), was investigated.

  8. These observations suggest that NHE6 regulates clathrin-dependent endocytosis of transferrin (show Tf ELISA Kits) via pH regulation.

  9. In mineralizing osteoblasts, slightly basic basal intracellular pH is maintained, and external acid load is dissipated, by high-capacity Na(+) /H(+) exchange via NHE1 and NHE6.

  10. This review defines NHE6-9 as organellar NHEs that are fairly dynamic, implying that they are subjected to intracellular trafficking and thus they continuously shuttle between organelles and the plasma membrane.

SLC9A6 Antigen Profile

Antigen Summary

This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SLC9A6

  • solute carrier family 9 (sodium/hydrogen exchanger), member 6 (Slc9a6) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 7 (SLC9A7) antibody
  • solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 (SLC9A7) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 7 (slc9a7) antibody
  • solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (Slc9a6) antibody
  • solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 (SLC9A6) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 6 (SLC9A6) antibody
  • sodium/hydrogen exchanger 6 (PGTG_07402) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 6 (LOC100223682) antibody
  • solute carrier family 9 (sodium/hydrogen exchanger), member 6 (slc9a6) antibody
  • 3732426M05 antibody
  • 6430520C02Rik antibody
  • DKFZp459O1854 antibody
  • mKIAA0267 antibody
  • MRSA antibody
  • NHE6 antibody
  • nhe7 antibody
  • RGD1563582 antibody
  • slc9a6 antibody

Protein level used designations for SLC9A6

solute carrier family 9 (sodium/hydrogen exchanger) , solute carrier family 9 (sodium/hydrogen exchanger), member 7 , sodium/hydrogen exchanger 7-like , sodium/hydrogen exchanger 6 , solute carrier family 9 (sodium/hydrogen exchanger), member 6 , sodium/hydrogen exchanger 6-like , Na(+)/H(+) exchanger 6

GENE ID SPECIES
236794 Mus musculus
418676 Gallus gallus
522505 Bos taurus
609144 Canis lupus familiaris
710906 Macaca mulatta
100011742 Monodelphis domestica
100060383 Equus caballus
100151732 Xenopus (Silurana) tropicalis
100390494 Callithrix jacchus
100436764 Pongo abelii
100524182 Sus scrofa
302863 Rattus norvegicus
422241 Gallus gallus
473799 Pan troglodytes
481060 Canis lupus familiaris
533137 Bos taurus
10536554 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100171878 Pongo abelii
100223682 Taeniopygia guttata
100470354 Ailuropoda melanoleuca
100554712 Anolis carolinensis
100588872 Nomascus leucogenys
10479 Homo sapiens
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